| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| FtsE | FtsY | azo0767 | azo0766 | Probable cell division ATP-binding protein FtsE; High confidence in function and specificity. | Probable signal recognition particle-docing protein FtsY; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components. | 0.875 |
| FtsE | azo0763 | azo0767 | azo0763 | Probable cell division ATP-binding protein FtsE; High confidence in function and specificity. | Putative methylase; Family membership. | 0.550 |
| FtsE | azo0764 | azo0767 | azo0764 | Probable cell division ATP-binding protein FtsE; High confidence in function and specificity. | Probable Zn dependent peptidase; Hypothetical zinc protease-like protein y4wB. TREMBL:Q8Y2E8: 43% identity; 57% similarity. InterPro: Insulinase family (Peptidase family M16) InterPro:IPR001431; Peptidase_M16. IPR007863: Peptidase_M16_C. Pfam:PF00675; Peptidase_M16 (Insulinase); homoserine_dh; aldehyde dehydrogenase; PF05193:Peptidase_M16_C; precor6x_red: precorrin-6x reductase TIGRFAM:folate/biopterin transporter SignalP predicted signal peptide and TMHMM predicted transmembrane helix; Specificity unclear. | 0.584 |
| FtsE | azo0765 | azo0767 | azo0765 | Probable cell division ATP-binding protein FtsE; High confidence in function and specificity. | Probable Zn dependent peptidase; TREMBL:Q8Y2E9: 55% identity, 68% similarity. Hypothetical zinc protease y4wA. InterPro:IPR001431; Peptidase_M16. IPR007863: Peptidase_M16_C. cofactor:binds 1 zinc ion per subunit (by similarity). belongs to peptidase family m16. similarity:to y4wb. Pfam:PF00675; Peptidase_M16; 1. PF05193:Peptidase_M16_C TIGRFAM: uxuA SignalP predicted signal peptide and TMHMM predicted transmembrane helices menD: 2-succinyl-6-hydroxy-24-cyclohex; Specificity unclear. | 0.596 |
| FtsE | coaD | azo0767 | azo0762 | Probable cell division ATP-binding protein FtsE; High confidence in function and specificity. | Pantetheine-phosphate adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. | 0.529 |
| FtsE | fdx1 | azo0767 | azo0761 | Probable cell division ATP-binding protein FtsE; High confidence in function and specificity. | Probable ferredoxin. Homology to fdx of C. vinosum of 67% (sprot|FER_CHRVI). Ferredons are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions. Pfam: 4Fe-4S binding domain no signal peptide no TMHs; Family membership. | 0.511 |
| FtsY | FtsE | azo0766 | azo0767 | Probable signal recognition particle-docing protein FtsY; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components. | Probable cell division ATP-binding protein FtsE; High confidence in function and specificity. | 0.875 |
| FtsY | azo0763 | azo0766 | azo0763 | Probable signal recognition particle-docing protein FtsY; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components. | Putative methylase; Family membership. | 0.773 |
| FtsY | azo0764 | azo0766 | azo0764 | Probable signal recognition particle-docing protein FtsY; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components. | Probable Zn dependent peptidase; Hypothetical zinc protease-like protein y4wB. TREMBL:Q8Y2E8: 43% identity; 57% similarity. InterPro: Insulinase family (Peptidase family M16) InterPro:IPR001431; Peptidase_M16. IPR007863: Peptidase_M16_C. Pfam:PF00675; Peptidase_M16 (Insulinase); homoserine_dh; aldehyde dehydrogenase; PF05193:Peptidase_M16_C; precor6x_red: precorrin-6x reductase TIGRFAM:folate/biopterin transporter SignalP predicted signal peptide and TMHMM predicted transmembrane helix; Specificity unclear. | 0.559 |
| FtsY | azo0765 | azo0766 | azo0765 | Probable signal recognition particle-docing protein FtsY; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components. | Probable Zn dependent peptidase; TREMBL:Q8Y2E9: 55% identity, 68% similarity. Hypothetical zinc protease y4wA. InterPro:IPR001431; Peptidase_M16. IPR007863: Peptidase_M16_C. cofactor:binds 1 zinc ion per subunit (by similarity). belongs to peptidase family m16. similarity:to y4wb. Pfam:PF00675; Peptidase_M16; 1. PF05193:Peptidase_M16_C TIGRFAM: uxuA SignalP predicted signal peptide and TMHMM predicted transmembrane helices menD: 2-succinyl-6-hydroxy-24-cyclohex; Specificity unclear. | 0.606 |
| FtsY | coaD | azo0766 | azo0762 | Probable signal recognition particle-docing protein FtsY; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components. | Pantetheine-phosphate adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. | 0.589 |
| FtsY | fdx1 | azo0766 | azo0761 | Probable signal recognition particle-docing protein FtsY; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components. | Probable ferredoxin. Homology to fdx of C. vinosum of 67% (sprot|FER_CHRVI). Ferredons are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions. Pfam: 4Fe-4S binding domain no signal peptide no TMHs; Family membership. | 0.516 |
| FtsY | nnrD | azo0766 | azo2076 | Probable signal recognition particle-docing protein FtsY; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components. | Conserved hypothetical protein; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair o [...] | 0.551 |
| azo0763 | FtsE | azo0763 | azo0767 | Putative methylase; Family membership. | Probable cell division ATP-binding protein FtsE; High confidence in function and specificity. | 0.550 |
| azo0763 | FtsY | azo0763 | azo0766 | Putative methylase; Family membership. | Probable signal recognition particle-docing protein FtsY; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components. | 0.773 |
| azo0763 | azo0764 | azo0763 | azo0764 | Putative methylase; Family membership. | Probable Zn dependent peptidase; Hypothetical zinc protease-like protein y4wB. TREMBL:Q8Y2E8: 43% identity; 57% similarity. InterPro: Insulinase family (Peptidase family M16) InterPro:IPR001431; Peptidase_M16. IPR007863: Peptidase_M16_C. Pfam:PF00675; Peptidase_M16 (Insulinase); homoserine_dh; aldehyde dehydrogenase; PF05193:Peptidase_M16_C; precor6x_red: precorrin-6x reductase TIGRFAM:folate/biopterin transporter SignalP predicted signal peptide and TMHMM predicted transmembrane helix; Specificity unclear. | 0.809 |
| azo0763 | azo0765 | azo0763 | azo0765 | Putative methylase; Family membership. | Probable Zn dependent peptidase; TREMBL:Q8Y2E9: 55% identity, 68% similarity. Hypothetical zinc protease y4wA. InterPro:IPR001431; Peptidase_M16. IPR007863: Peptidase_M16_C. cofactor:binds 1 zinc ion per subunit (by similarity). belongs to peptidase family m16. similarity:to y4wb. Pfam:PF00675; Peptidase_M16; 1. PF05193:Peptidase_M16_C TIGRFAM: uxuA SignalP predicted signal peptide and TMHMM predicted transmembrane helices menD: 2-succinyl-6-hydroxy-24-cyclohex; Specificity unclear. | 0.735 |
| azo0763 | azo3990 | azo0763 | azo3990 | Putative methylase; Family membership. | Conserved hypothetical protein; Could be involved in insertion of integral membrane proteins into the membrane; Belongs to the UPF0161 family. | 0.790 |
| azo0763 | coaD | azo0763 | azo0762 | Putative methylase; Family membership. | Pantetheine-phosphate adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. | 0.973 |
| azo0763 | fdx1 | azo0763 | azo0761 | Putative methylase; Family membership. | Probable ferredoxin. Homology to fdx of C. vinosum of 67% (sprot|FER_CHRVI). Ferredons are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions. Pfam: 4Fe-4S binding domain no signal peptide no TMHs; Family membership. | 0.792 |