Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ahpCAlkyl hydroperoxide reductase subunit C; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides; Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily. (187 aa)    
Predicted Functional Partners:
ahpF
Alkyl hydroperoxide reductase subunit F. Homology to aphF of X. campestris of 71% (sprot|AHPF_XANCH) Serves to protect the cell against DNA damage by alkyl hydroperoxides. It can use either NADH or NADPH as electron donor for direct reduction of redox dyes or of alkyl hydroperoxides when combined with the AHPC protein. Pfam: Pyridine nucleotide-disulphide oxidareductase no TMHs; High confidence in function and specificity.
 
 
 0.996
rubA
Probable rubredoxin. Homology to ruba of A. calcoaceticus of 42% (sprot|RUBR_ACIAD). Involved in the hydrocarbon hydroxylating system to convert dodecane to lauric acid, which transfers electrons from NADH to rubredoxin reductase and then through rubredoxin to alkane 1 monooxygenase. Pfam: Rubredoxin no singal peptide no TMHs; Family membership.
  
  
 0.811
sodC
Superoxide dismutase; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the Cu-Zn superoxide dismutase family.
   
 
 0.805
trxB1
Putative thioredoxin reductase. Homology to trxB of S. coelicolor of 25% (sprot|TRXB_STRCO). Catalyse the reaction: thioredoxin + nadp(+) = thioredoxin disulfide + nadph. InterPro: FAD-dependent pyridine nucleotide-disulphide oxidoreductase (IPR001327) Pfam: Pyridine nucleotide-disulphide oxidoreductase no signal peptide no TMHs; Family membership.
  
 
 0.799
trxB2
Thioredoxin-disulfide reductase(EC 1.8.1.9). Homology to trxB of E. coli of 71% (sprot|TRXB_ECOLI). Catalyse the reaction: thioredoxin + nadp(+) = thioredoxin disulfide + nadph Pfam: Pyridine nucleotide-disulphide oxidoreductase signal peptide no TMHs; High confidence in function and specificity.
  
 
 0.799
fur
Ferric uptake regulation protein (Ferric uptake regulator)Fur. Acts as a global negative controlling element employing Fe(2+) as a cofactor to bind the operator of the repressed genes. Regulator for biosynthesis of the siderophore alcaligin E. InterPro: Ferric uptake regulator family TIGR00011: conserved hypothetical protein; High confidence in function and specificity.
  
  
 0.791
azo3768
Putative catalase; Serves to protect cells from the toxic effects of hydrogen peroxide.
  
 
 0.779
azo2231
Putative Mannose-1-phosphate guanylyltransferase; Mannose-1-phosphate guanyltransferase involved in the reaction:GTP + alpha-D-mannose 1-phosphate = diphosphate + GDPmannose. 51% Hexapep_transf.IPR005835; NTP_transferase. Pfam:PF00132; Hexapep; 2.PF00483; NTP_transferase; 1; High confidence in function and specificity.
    
  0.717
azo2889
Nucleotidyltransferase; Specificity unclear.
    
  0.717
azo0866
Hypothetical thioredoxin. Homology with BPP3919 of B. parapertussis of 38%. Participates in various redox reactions through the reversible oxidation of the active center dithiol to a disulfide. Tigrfam: dsbE: periplasmic protein thiol:disulfi signal peptide probable 1 TMHs; Family membership.
  
 0.712
Your Current Organism:
Azoarcus sp. BH72
NCBI taxonomy Id: 62928
Other names: A. sp. BH72
Server load: low (20%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.