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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
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second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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[Homology]
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azo0788Probable acyltransferase; Acyl-[acyl-carrier protein] can also acts as acyl donor.The animal enzyme is specific for the transfer of unsaturated fatty acyl groups. Catalytic Activity:-Acyl-CoA + 1-acyl-sn-glycerol 3-phosphate = CoA + 1,2-diacyl-sn-glycerol 3-phosphate. Entry name TREMBL:Q82VB2 Prim. accession # Q82VB2 InterPro:-IPR002123; Acyltransferase. Pfam:- PF01553; Acyltransferase; 1. Identity:- 56% Prediction: Signal peptide Signal peptide probability: 0.907 Number of predicted TMHs: 1; Family membership. (252 aa)    
Predicted Functional Partners:
plsY
Conserved hypothetical membrane protein; Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.
  
 
 0.954
cdsA
Phosphatidate cytidylyltransferase :- catalytic activity ctp + phosphatidate = diphosphate + cdp-diacylglycerol. pathway :-phospholipid biosynthesis. Entry name:- CDSA_ECOLI Primary accession number :- P06466 InterPro:- IPR000374; PC_trans. Identities = 89/252 (35%) Pfam PF01148; CTP_transf_1; 1. Number of predicted TMHs: 7 Prediction: Signal peptide Signal peptide probability: 1.0; Family membership; Belongs to the CDS family.
 
  
 0.950
gpsA
Probable NAD-dependent glycerol-3-phosphate dehydrogenase [NAD(P)+]. Homology to gpsA of B. subtilis of 41% (SWISSPROT:GPDA_BACSU). NAD-dependent glycerol-3-phosphate dehydrogenase catalyzes the reversible reduction of dihydroxyacetone phosphate to glycerol-3-phosphate. InterPro: NAD-dependent glycerol-3-phosphate dehydrogenase (IPR006109) Pfam: NAD-dependent glycerol-3-phosphate dehydrogeanse signal peptide no TMHs apbA_panE: 2-dehydropantoate 2-reductas; High confidence in function and specificity.
    
 0.879
plsC
Putative 1-acyl-sn-glycerol-3-phosphate acyltransferase; Function:-Converts lysophosphatidic acid (LPA) into phosphatidic acid by incorporating acyl moiety at the 2 position (By similarity). CATALYTIC ACTIVITY: Acyl-CoA + 1-acyl-sn-glycerol 3-phosphate = CoA + 1,2-diacyl-sn-glycerol 3-phosphate. Entry name:- PLSC_NEIGO Primary accession number :- Q59601 InterPro IPR002123; Acyltransferase. IPR004552; AGP_acyltrn. Pfam PF01553; Acyltransferase; 1. Identities = 68/182 (37%) Prediction: Non-secretory protein Signal peptide probability: 0.096 Number of predicted TMHs: 0; Family membership.
     
 0.865
dgkA
Probable diacylglycerol kinase; Recycling of diacylglycerol produced during the turnover of membrane phospholipid.
     
 0.864
glpA
Putative glycerol-3-phosphate dehydrogenase. Homology to glpA of B. hermsir of 38% (trembl|Q84I21) FAD-dependent glycerol-3-phosphate dehydrogenase catalyzes the conversion of glycerol-3-phosphate into dihydroxyacetone phosphate: sn-glycerol-3-phosphate + acceptor = glycerone phosphate + reduced acceptor. InterPro: D-amino acid oxidase (IPR000927) Pfam: FAD dependent oxidoreductase no signal peptide no TMHs gidA: glucose-inhibited division prot; Family membership.
    
 0.852
azo0668
Conserved hypothetical phoshpatidate cytidyltransferase. Homology to pa2536 of P. aeruginosa (trembl|Q9I0U8). Phosphatidate cytidylyltransferase is the enzyme that catalyzes the synthesis of CDP-diacylglycerol from CTP and phosphatidate (PA): CTP + phosphatidate = diphosphate + CDP-diacylglycerol Pfam: Phospatidate cytidyltransferase signal peptide 7 TMHs InterPro: Phosphatidate cytidylyltransferase stp: serine transporter; Family membership.
  
 
 0.773
azo0787
Putative haloacid dehalogenase-like hydrolase, 60% Identity to TrEMBL;Q7W4K4,Q7WG29,Q7W0Q4. Has PF00702,haloacid dehalogenase-like hydrolase; IPR005834 Dehal_like_hydro; This family are structurally different from the alpha/ beta hydrolase family (Abhydrolase_1). This family includes L-2-haloacid dehalogenase, epoxide hydrolases and phosphatases. The structure of the family consists of two domains. One is an inserted four helix bundle, which is the least well conserved region of the alignment, between residues 16 and 96 of P24069. The rest of the fold is composed of the core alpha/beta [...]
  
  
 0.772
plsX
Probable fatty acid/phospholipid synthesis protein plsX; Catalyzes the reversible formation of acyl-phosphate (acyl- PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA.
  
 
 0.706
glyQ
Glycyl-tRNA synthetase alpha chain (EC 6.1.1.14) (Glycine--tRNA ligase alpha chain) (GlyRS); High confidence in function and specificity.
       0.651
Your Current Organism:
Azoarcus sp. BH72
NCBI taxonomy Id: 62928
Other names: A. sp. BH72
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