STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
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Textmining
[Homology]
Score
azo0795Probable glutathione-regulated potassium-efflux system protein (K(+)/H(+) antiporter). Transport system that facilitate potassium-efflux possibly by potassium-proton antiport. 50% Na_H_porter.IPR006037; TrkAC.IPR003148; TrkA_N. Pfam: PF00999; Na_H_Exchanger; 1.PF02080; TrkA_C; 1.PF02254; TrkA_N; 1. TMhelix: 11; High confidence in function and specificity; Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2.A.37) family. (655 aa)    
Predicted Functional Partners:
nqo1
NAD(P)H dehydrogenase [quinone] 1 (EC 1.6.5.2) (Quinone reductase 1) (QR1) (DT-diaphorase) (DTD) (Azoreductase) (Phylloquinone reductase) (Menadione reductase). The enzyme apparently serves as a quinone reductase in connection with conjugation reactions of hydroquinons involved in detoxification pathways as well as in biosynthetic processes such as the vitamin K-dependent gamma-carboxylation of glutamate residues in prothrombin synthesis (By similarity). trembl:Q9I4B4:72%identity; 81% similarity InterPro: NAD(P)H dehydrogenase (quinone) InterPro:IPR003680; NADHdh_2. Pfam:PF02525; Flavo [...]
 
 
 
 0.923
drgA
Putative NAD(P)H oxidoreductase HI1544 (EC 1.6.5.2). trembl:Q88J60: 64% identity; 80% similarity This family consists of bacterial and eukaryotic NAD(P)H dehydrogenase (quinone) EC: 1.6.5.2 that catalyses the NAD(P)H-dependent two-electron reductions of quinones and protect cells against damage by free radicals and reactive oxygen species [1]. This enzyme uses a FAD co-factor InterPro:IPR003680; NADHdh_2. Pfam:PF02525; Flavodoxin_2 SignalP predicted signal peptide present No transmembrane helices (TMHMM predicted); High confidence in function and specificity.
   
 
 0.912
flgG
Flagellar basal-body rod protein flgG (Distal rod protein). The rod has been shown to consist of four different, yet evolutionary related proteins: in the distal portion of the rod there are about 26 subunits of protein flgG and in the proximal portion there are about six subunits each of proteins flgB, flgC, and flgF. These four proteins contain a highly conserved asparagine-rich domain at their N terminus. InterPro: Flagella basal body rod protein no signal peptide no TMHs; High confidence in function and specificity.
    
   0.858
azo0794
Arabinose 5-phosphate isomerase (EC 5.3.1.13). Catalyzes the interconversion of D-arabinose 5-phosphate and D-ribulose 5-phosphate (By similarity). InterPro: KpsF/GutQ family protein kpsF: KpsF/GutQ family protein; High confidence in function and specificity; Belongs to the SIS family. GutQ/KpsF subfamily.
     
 0.724
azo0792
Conserved hypothetical secreted protein. Homology to ebA1318 of Azoarcus sp. EbN1 of 47% (gnl|keqq|eba:ebA1318(KEGG)). Has PF06835, Protein of unknown function (DUF1239);IPR010664;This family consists of several hypothetical bacterial proteins of around 190 residues in length. The function of this family is unknown. No TMHs. Signal peptide; Conserved hypothetical protein.
       0.691
azo0793
Probable phosphatase (HAD superfamily); Catalyzes the hydrolysis of KDO 8-P to KDO and inorganic phosphate TREMBL:Q9JSU3: 43% identity, 59% similarity InterPro: IPR006549; HAD-SF-IIIA. IPR005834; Hydrolase. IPR008230; Sugar_Ptase. IPR010023; YrbI_phosphatas. Pfam: PF00702; Hydrolase TIGR00099: conserved hypothetical prote Absence of transmembrane helices; Specificity unclear.
       0.691
lptA
Conserved hypothetical secreted protein; Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane.
       0.688
rosB
Putative Potassium/proton antiporter; Probable potassium antiporter, rosB. 38% HPr_SerP_S.IPR004771; K_eff.IPR006153; Na_H_porter. IPR003148; TrkA_N. Pfam:PF00999; Na_H_Exchanger; 1.PF02254; TrkA_N; 1. TIGRFAMs:TIGR00932; 2a37; 1. TMhelix: 12; High confidence in function and specificity; Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2.A.37) family.
 
   
0.655
sulP1
Putative sulfate transporter; Sulfate permease, SulP. Permease member of the MFS superfamily, involved in the transport of sulfate. Putative sulfate transporter ychM. InterPro: IPR002645; STAS. IPR001902; Sulph_transpt. Pfam: PF01740; STAS; 1. PF00916; Sulfate_transp; 1. SignalP: present. HIGH-AFFINITY H+/SULFATE COTRANSPORTER THAT MEDIATES THE UPTAKE OF SULFATE BY PLANT ROOTS FROM LOW CONCENTRATIONS OF SULFATE IN THE SOIL SOLUTION; High confidence in function and specificity.
    
 0.521
sulP2
Putative sulfate transporter; Sulfate permease, SulP. Permease member of the MFS superfamily, involved in the transport of sulfate. Putative sulfate transporter ychM. InterPro: IPR002645; STAS. IPR001902; Sulph_transpt. Pfam: PF01740; STAS; 1. PF00916; Sulfate_transp; 1. SignalP: present; High confidence in function and specificity.
    
 0.521
Your Current Organism:
Azoarcus sp. BH72
NCBI taxonomy Id: 62928
Other names: A. sp. BH72
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