STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
azo0810Conserved hypothetical secreted protein. Similar to TREMBL:Q82SF8 (54% identity); TREMBL:Q8XV73 (42% identity); TREMBL:Q7VSZ6 (40% identity). SignalP reporting signal peptide. no TMHs; Conserved hypothetical protein. (215 aa)    
Predicted Functional Partners:
azo0808
Conserved hypothetical secreted protein. Similar to TREMBL:Q8XV71 (59% identity); TREMBL:Q82SF7 (55% identity); TREMBL:Q7VSZ8 (55% identity). Pfam (PF02470): mce related protein. This family of proteins contains the mce (mycobacterial cell entry) proteins from Mycobacterium tuberculosis. The archetype (Rv0169), was isolated as being necessary for colonisation of, and survival within,the macrophage. This family contains proteins of unknown function from other bacteria. SignalP reoprting signal peptide. TMH in signal peptide; Family membership.
 
 0.998
azo0811
Conserved hypothetical protein. Homology to rsc2957 of R. solanacearum of 42% (trembl|Q8XV74). Pfam: STAS domain The STAS (after Sulphate Transporter and AntiSigma factor antagonist) domain is found in the C terminal region of Sulphate transporters and bacterial antisigma factor antagonists. It has been suggested that this domain may have a general NTP binding function. no signal peptide no TMHs.
  
 
 0.981
azo0807
Conserved hypothetical membrane protein Similar to TREMBL:Q7P0W7 (65% identity); TREMBL:Q82SF6 (65% identity); TREMBL:Q7VSZ9 (57% identity). InterPro (IPR003453): Domain of unknown function DUF140. Pfam (PF02405): Domain of unknown function DUF140. TIGRFAM (TIGR00056): Conserved hypothetical protein. TMHMM reporting five transmembrane helices.
 
 
 0.978
vacJ
Putative surface lipoprotein. Homology to vacJ of S. flexneri of 26% (sprot|VACJ_SHIFL) Required for intercellular spreading. Pfam: VacJ like lipoprotein signal peptide no TMHs; Family membership.
 
 
 
 0.977
azo0806
Conserved hypothetical ABC transporter ATP-binding protein. Homology to rs01335 of R. solanacearum of 67% (trembl|Q8XV69). ATP-binding cassette (ABC) transporters are multidomain membrane proteins, responsible for the controlled efflux and influx of substances (allocrites) across cellular membranes. They are minimally composed of four domains, with two transmembrane domains (TMDs) responsible for allocrite binding and transport and two nucleotide-binding domains (NBDs) responsible for coupling the energy of ATP hydrolysis to conformational changes in the TMDs. Both NBDs are capable of [...]
 
 
 0.967
azo1693
Conserved hypothetical secreted protein. Homology to bb0165 of B. bronchiseptica of 31% (TREMBL:Q7WR07). Pfam: mce related protein This family of proteins contains the mce (mycobacterial cell entry) proteins from Mycobacterium tuberculosis. The archetype (Rv0169), was isolated as being necessary for colonisation of, and survival within, the macrophage. This family contains proteins of unknown function from other bacteria. Signal peptide. no TMHs; Conserved hypothetical protein.
  
 0.958
azo1691
Conserved hypothetical membrane protein. Similar to TREMBL:Q8Y2M2 (43% identity). InterPro (IPR003453): Domain of unknown function DUF140. Pfam (PF02405): Domain of unknown function DUF140. TIGRFAM (TIGR00056): Conserved hypothetical protein. TMHMM reporting five transmembrane helices.
  
 
 0.878
azo1692
ATP-binding cassette (ABC) transporters form a large family of proteins responsible for translocation of a variety of compounds across biological membranes. They are composed of two transmembrane domains responsible for binding and transport and two nucleotide-binding domains responsible for coupling the energy of ATP hydrolysis to conformational changes in the TMDs, TREMBL:Q7W0L5 (51% identity); TREMBL:Q9A5X8 (46% identity). InterPro (IPR001687): ATP/GTP-binding site motif A (P-loop). InterPro (IPR003593): AAA ATPase. InterPro (IPR003439): ABC transporter. Pfam (PF00005): ABC transpor [...]
  
 
 0.865
azo1272
Conserved hypothetical secreted protein. Similar to TREMBL:Q9HZ27 (53% identity); TREMBL:Q88RI9 (46% identity); TREMBL:Q8PGP4 (33% identity). Pfam (PF02470): mce related protein. SignalP reporting signal peptide. No TMHs; Conserved hypothetical protein.
  
 0.813
azo0812
ATP-binding cassette (ABC) transporters form a large family of proteins responsible for translocation of a variety of compounds across biological membranes. They are composed of two transmembrane domains responsible for binding and transport and two nucleotide-binding domains responsible for coupling the energy of ATP hydrolysis to conformational changes in the TMDs, TREMBL:Q7P0X8 (62% identity); TREMBL:Q82SG0 (58% identity). InterPro (IPR003593): AAA ATPase. InterPro (IPR001687): ATP/GTP-binding site motif A (P-loop). InterPro (IPR003439): ABC transporter. Pfam (PF00005): ABC transpor [...]
  
 
  0.726
Your Current Organism:
Azoarcus sp. BH72
NCBI taxonomy Id: 62928
Other names: A. sp. BH72
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