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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
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second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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azo0812ATP-binding cassette (ABC) transporters form a large family of proteins responsible for translocation of a variety of compounds across biological membranes. They are composed of two transmembrane domains responsible for binding and transport and two nucleotide-binding domains responsible for coupling the energy of ATP hydrolysis to conformational changes in the TMDs, TREMBL:Q7P0X8 (62% identity); TREMBL:Q82SG0 (58% identity). InterPro (IPR003593): AAA ATPase. InterPro (IPR001687): ATP/GTP-binding site motif A (P-loop). InterPro (IPR003439): ABC transporter. Pfam (PF00005): ABC transpor [...] (298 aa)    
Predicted Functional Partners:
azo0813
ABC-2 type transporter permease protein; Similar to TREMBL:Q8XV76 (69% identity); TREMBL:Q7P0X7 (66% identity); TREMBL:Q82SG1 (64% identity). InterPro (IPR000412): ABC transporter, family 2. Pfam (PF01061): ABC-2 type transporter. TMHMM reporting seven transmembrane helices. TC (3.A.1): The ATP-binding Cassette (ABC) Superfamily; Specificity unclear.
 
 0.989
azo0811
Conserved hypothetical protein. Homology to rsc2957 of R. solanacearum of 42% (trembl|Q8XV74). Pfam: STAS domain The STAS (after Sulphate Transporter and AntiSigma factor antagonist) domain is found in the C terminal region of Sulphate transporters and bacterial antisigma factor antagonists. It has been suggested that this domain may have a general NTP binding function. no signal peptide no TMHs.
    
  0.926
azo1127
ATP-binding cassette (ABC) transporters are multidomain membrane proteins, responsible for the controlled efflux and influx of substances (allocrites) across cellular membranes. ATP binding domains are responsible for coupling the energy of ATP hydrolysis to conformational changes in the ransmembrane domains. Similar to trembl|Q7W058 (49%) and to sprot|LIVG_ECOLI (39%). Pfam (PF00005): ABC transporter Smart (SM00382): AAA ATPase superfamily; Specificity unclear.
 
  
 
0.848
azo0807
Conserved hypothetical membrane protein Similar to TREMBL:Q7P0W7 (65% identity); TREMBL:Q82SF6 (65% identity); TREMBL:Q7VSZ9 (57% identity). InterPro (IPR003453): Domain of unknown function DUF140. Pfam (PF02405): Domain of unknown function DUF140. TIGRFAM (TIGR00056): Conserved hypothetical protein. TMHMM reporting five transmembrane helices.
    
 0.826
nodJ
ABC transporter permease NodJ; Forms with NodI a membrane transport complex involved in the nodulation process. it probably exports a modified beta-1,4-linked n-acetylglucosamine oligosaccharide. Belongs to the ABC-2 integral membrane protein family, TREMBL:Q7WHD1 (49% identity); SWISSPROT:O52619 (49% identity). InterPro (IPR000412): ABC transporter, family 2. Pfam (PF01061): ABC-2 type transporter. TMHMM reporting six transmembrane helices. TC (3.A.1.102): The Lipooligosaccharide Exporter (LOSE) Family; High confidence in function and specificity.
 
 
 0.788
nosY
Membrane protein nosY precursor.INVOLVED IN COPPER PROCESSING. Part of the ABC transporter complex nosDFY involved in copper import. Probably responsible for the translocation of the substrate across the membrane. 43% Similar to the copper permease protein, nosY in P.stutzeri. TREMBL:Q9F0W1 InterPro:IPR001117; Cu-oxidase. SignalP: present. Number of predicted TMHs:6; High confidence in function and specificity.
  
 0.757
azo0814
Conserved hypothetical BolA-like protein. Homology to ne2377 of N. europaea of 47% (trembl|Q82SG2). InterPro: BolA-like protein This family consist of the morphoprotein BolA from E. coli and its various homologues. In E. coli over expression of this protein causes round morphology and may be involved in switching the cell between elongation and septation systems during cell division. The expression of BolA is growth rate regulated and is induced during the transition into the the stationary phase. BolA is also induced by stress during early stages of growth and may have a general role [...]
       0.754
cbiO
Putative cobalt transport system ATP-binding protein; Part of the ABC transporter complex cbiKMQO involved in cobalt import. Probably responsible for the translocation of the substrate across the membrane. 40% AAA_ATPase.IPR003439; ABC_transporter. Pfam:PF00005; ABC_tran; 1. ProDom; PD000006; ABC_transporter; 1. SMART; SM00382; AAA; 1; High confidence in function and specificity.
 
  
 
0.743
azo0810
Conserved hypothetical secreted protein. Similar to TREMBL:Q82SF8 (54% identity); TREMBL:Q8XV73 (42% identity); TREMBL:Q7VSZ6 (40% identity). SignalP reporting signal peptide. no TMHs; Conserved hypothetical protein.
  
 
  0.726
azo3353
Conserved hypothetical membrane protein; In Myxococcus xanthus pilI are co-transcribed with pilH an ABC transporter homologue required for type IV pilus biogenesis and social gliding. pilI appear to be functionally related to pilH. Similar to membrane protein of Geobacter sulfurreducens PCA (14%) and weak; Conserved hypothetical protein.
  
 0.722
Your Current Organism:
Azoarcus sp. BH72
NCBI taxonomy Id: 62928
Other names: A. sp. BH72
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