STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
azo0822Probable Hypothetical UPF0028 family protein YML059C. TREMBL:Q82SM1: 50% identity, 68% similariry InterPro:IPR002641; Patatin. Pfam:PF01734; Patatin bioF: 8-amino-7-oxononanoate synthase Signal peptide present (SinalP predicted) TMHMM predicted TMH's; Function unclear. (378 aa)    
Predicted Functional Partners:
maeB1
Probable malate dehydrogenase (oxaloacetate-decarboxylating) (NADP+) (EC 1.1.1.40) (NADP-ME). Homology to dme of S. meliloti of 60% (sprot|MAO1_RHIME). Required for symbiotic nitrogen fixation. Plays a key role in the conversion of malate to acetyl-CoA for efficient tricarboxylic acid cycle function in nitrogen-fixating bacteria. Tigrfam: pta: phosphotransacetylase Pfam: Malic enzyme; Phosphate acetyl/butaryltransferase no signal peptide no TMHs; High confidence in function and specificity.
       0.648
azo1783
Conserved hypothetical membrane protein. Homology to ebA6946 of Azoarcus sp. EbN1 of 64% (gnl|keqq|eba:ebA6946(KEGG)). Pfam: Pospholipase D, active site motife; DedA family. no signal peptide. 6 TMHs; Conserved hypothetical protein.
    
 0.623
aas
AAS bifunctional protein [Includes: 2-acylglycerophosphoethanolamine acyltransferase (2-acyl-GPE acyltransferase); Acyl-acyl carrier protein synthetase (Acyl-ACP synthetase)]. PLAYS A ROLE IN LYSOPHOSPHOLIPID ACYLATION. TRANSFERS FATTY ACIDS TO THE 1-POSITION VIA AN ENZYME-BOUND ACYL-ACP INTERMEDIATE IN THE PRESENCE OF ATP AND MG(2+). ITS PHYSIOLOGICAL FUNCTION IS TO REGENERATE PTDETN FROM 2-ACYL-GPE FORMED BY TRANSACYLATION REACTIONS OR DEGRADATION BY PHOSPHOLIPASE A1, TREMBL:Q8FEA6 (52% identity); SWISSPROT:P31119 (52% identity). Pfam (PF00501): AMP-binding enzyme. Pfam (PF01553): Ac [...]
    
  0.524
azo3955
Conserved hypothetical protein. Homology to Daro03000439 of Dechloromonas aromatica of 48% (gi|41725494|ref|ZP_00152252.1|(NBCI ENTREZ)). No domains predicted. No signal peptide. No TMHs.
  
     0.439
fadE
Probable acyl-CoA dehydrogenase. Homology to fadE of E. coli of 55% (trembl|Q8KTJ8(SRS)) Catalyzes the dehydrogenation of acyl-CoA (By similarity). Reaction: acyl-CoA + acceptor = 2,3-dehydroacyl-CoA + reduced acceptor. InterPro: Acyl-CoA dehydrogenase (IPR006089) Pfam: Acyl-CoA dehydrogenase, N-terminal domain; Acyl-CoA dehydrogenase, C-terminal domain signal peptide 2 TMHs; High confidence in function and specificity.
  
     0.429
Your Current Organism:
Azoarcus sp. BH72
NCBI taxonomy Id: 62928
Other names: A. sp. BH72
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