Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
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experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
azo0828Putative RNA pseudouridylate synthase. Homology with hits in the database only for the first half of protein. Has PF00849, RNA pseudouridylate synthase; IPR006145, PseudoU_synth; Members of this family are involved in modifying bases in RNA molecules. They carry out the conversion of uracil bases to pseudouridine. This family includes RluD P33643, a pseudouridylate synthase that converts specific uracils to pseudouridine in 23S rRNA. RluA from E. coli converts bases in both rRNA and tRNA. Has SMART;SM00363, S4 RNA-binding domain;IPR002942;The S4 domain is a small domain consisting of 6 [...] (500 aa)    
Predicted Functional Partners:
aroA
3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate; Belongs to the cytidylate kinase family. Type 1 subfamily.
 
  
 0.774
engA
Probable GTP-binding protein; GTPase that plays an essential role in the late steps of ribosome biogenesis; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
 
  
 0.695
azo2880
Exodeoxyribonuclease III; Region start changed from 3161811 to 3162171 (-360 bases).
  
    0.631
xthA2
Exodeoxyribonuclease (EC 3.1.11.2). InterPro: AP endonucleases family 1; High confidence in function and specificity.
  
    0.631
rplU
50S ribosomal protein L21; This protein binds to 23S rRNA in the presence of protein L20; Belongs to the bacterial ribosomal protein bL21 family.
 
 
   0.619
scpB
Putative segregation and condensation protein B; Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves.
  
  
 0.592
efp
Putative elongation factor P; Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.
 
   
 0.587
azo0827
Conserved hypothetical membrane protein. Homology to ORF428 of Roseateles depolymerans of 64% (tremble:BAB1967) Has PF07399:(IPR009978)Protein of unknown function (DUF1504); This family consists of several hypothetical bacterial proteins of around 440 residues in length. The function of this family is unknown; Conserved hypothetical protein.
 
     0.555
azo0709
Putative exoribonuclease II (EC: 3.1.13.1), RNase R.
 
 
   0.535
azo1893
RNA methyltransferase; Region start changed from 2079087 to 2078673 (-414 bases); Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.
 
   
 0.492
Your Current Organism:
Azoarcus sp. BH72
NCBI taxonomy Id: 62928
Other names: A. sp. BH72
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