STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
azo0845Conserved hypothetical transcriptional regulator. Homology to RSc0698 of alstonia solanacearum of 48% (gnl|keqq|rso:RS01603(KEGG)). InterPro: IPR001647 HTH_TetR. Pfam: PF00440 Bacterial regulatory proteins,tetR family. HTH reporting nucleic acid binding motif. No signal peptide. No TMHs; Conserved hypothetical protein. (225 aa)    
Predicted Functional Partners:
azo0847
RND efflux transporter, permease protein; AcrB/AcrD/AcrF family. Members of this family are integral membrane proteins. Some are involved in drug resistance. AcrB cooperates with a membrane fusion protein, AcrA, and an outer membrane channel TolC. The structure shows the AcrB forms a homotrimer, TREMBL:Q9A7D5 (35% identity); TREMBL:Q9HXW4 (55% identity). Pfam (PF00873): AcrB/AcrD/AcrF family. TIGRFAM (TIGR00914): Heavy metal efflux pump, CzcA family. TIGRFAM (TIGR00915): Hydrophobe/Amphiphile Efflux-1 (HAE1) Family protein. TMHMM predicting 12 transmembrane helices. TC (2.A.6.2): The ( [...]
 
     0.834
azo0846
Membrane fusion protein; Similar to TREMBL:Q7NR61 (35% identity); TREMBL:Q8XYV3 (33% identity); TREMBL:Q88MQ4 (32% identity). InterPro (IPR006143): Secretion protein HlyD. SignalP predicting signal peptide. TC (2.A.6.1): The Heavy Metal Efflux (HME) Family; Family membership; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
       0.773
azo0849
Conserved hypothetical sulfurtransferase protein; Putative rhodanese-related sulfurtransferase. TIGR:NMB1884. InterPro:IPR001763; Rhodanese-like. InterPro: Rhodanese/cdc25 fold. Pfam:PF00581; Rhodanese; 1; Function unclear.
 
     0.676
pcm1
Putative protein-L-isoaspartate O-methyltransferase (EC 2.1.1.77) Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and/or degradation of damaged proteins (By similarity). InterPro: Protein-L-isoaspartate(D-aspartate) O-methyltransferase (IPR000682), SAM binding motif (IPR000051) Tigrfam: pimt: protein-L-isoaspartate O-methyltransfase Pfam: Protein-L-isoaspartate (D-aspartate) O-methyltransferase no signal peptide no TMHs; High c [...]
   
   0.663
tolC
Putative outer membrane effluxe protein protein. Homology to tolC from E. coli of 33%. The OEP family (outer membreane effluxe protein) allow export of a variety of substrates in Gram negative bacteria. TolC is believed to be a membre af an ABC transporter system for protein secretion without cleavage of a signal sequence. Pfam: Outer membrane efflux protein Signal peptide no TMHs; Family membership.
     
 0.608
azo0844
Hypothetical secreted protein. No homology to the data base. No domain predicted. No TMHs. Signal peptide.
       0.550
azo1011
Conserved hypothetical secreted protein. Homology to Rgel02001790 of Rubrivivax gelatinosus of 45% (gi|47573892|ref|ZP_00243929.1|(NBCI ENTREZ)). No domains predicted. No TMHs. Signal peptide present; Conserved hypothetical protein.
  
     0.445
azo0422
Hypothetical protein; SPROT:P37718: 26% identity, 43% similarity Cellulose synthase operon protein C precursor. Required for maximal bacterial cellulose synthesis. InterPro: STAS domain. The STAS (Sulphate Transporter and AntiSigma factor antagonist) domain is found in the C-terminal region of sulphate transporters and bacterial anti-sigma factor antagonists. It has been suggested that this domain may have a general NTP binding function. InterPro:IPR008410; BCSC_C. IPR003921; Cell_synth_C. Pfam:PF05420; BCSC_C; 1. ant_ant_sig: anti-anti-sigma factor No signal peptide present SignalP pr [...]
  
     0.437
azo0760
Conserved hypothetical protein; TREMBL:Q8Y2D6:42% identity, 59% similarity Hypothetical protein in xynA 3region (ORF6) (Fragment). Pfam:dynamin_2 :Dynamin central region; FH2:Formin Homology 2 Domain surE: stationary-phase survival prote No transmembrane helices(TMHMM predicted); Function unclear.
  
     0.415
dctS
Two-component sensor kinase; C4-dicarboxylate transport sensor protein,; High confidence in function and specificity.
  
 
 
 0.415
Your Current Organism:
Azoarcus sp. BH72
NCBI taxonomy Id: 62928
Other names: A. sp. BH72
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