Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
azo0849Conserved hypothetical sulfurtransferase protein; Putative rhodanese-related sulfurtransferase. TIGR:NMB1884. InterPro:IPR001763; Rhodanese-like. InterPro: Rhodanese/cdc25 fold. Pfam:PF00581; Rhodanese; 1; Function unclear. (107 aa)    
Predicted Functional Partners:
azo2804
Adenylyltransferase, putative; Dinucleotide-utilizing enzyme involved in molybdopterin and/or thiamine biosynthesis Belongs to the hesA/moeB/thiF family, by similarity. TIGR00292: thiazole biosynthesis enzyme; High confidence in function and specificity.
   
 0.951
pcm1
Putative protein-L-isoaspartate O-methyltransferase (EC 2.1.1.77) Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and/or degradation of damaged proteins (By similarity). InterPro: Protein-L-isoaspartate(D-aspartate) O-methyltransferase (IPR000682), SAM binding motif (IPR000051) Tigrfam: pimt: protein-L-isoaspartate O-methyltransfase Pfam: Protein-L-isoaspartate (D-aspartate) O-methyltransferase no signal peptide no TMHs; High c [...]
       0.815
ybeY
Conserved hypothetical protein; Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.
    
  0.788
tolC
Putative outer membrane effluxe protein protein. Homology to tolC from E. coli of 33%. The OEP family (outer membreane effluxe protein) allow export of a variety of substrates in Gram negative bacteria. TolC is believed to be a membre af an ABC transporter system for protein secretion without cleavage of a signal sequence. Pfam: Outer membrane efflux protein Signal peptide no TMHs; Family membership.
       0.772
rpsQ
30S ribosomal protein S17; One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
   
  0.759
truA
Pseudouridine synthase A; Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
   
 0.713
azo0845
Conserved hypothetical transcriptional regulator. Homology to RSc0698 of alstonia solanacearum of 48% (gnl|keqq|rso:RS01603(KEGG)). InterPro: IPR001647 HTH_TetR. Pfam: PF00440 Bacterial regulatory proteins,tetR family. HTH reporting nucleic acid binding motif. No signal peptide. No TMHs; Conserved hypothetical protein.
 
     0.682
azo1466
Putative superoxide dismutase; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family.
   
 0.652
sseA
SseA: putative thiosulfate sulfurtransferase (rhodanese-like protein) [EC:2.8.1.1]. This protein transfers a sulfur ion to cyanide or to other thiol compounds. Also has weak rhodanese activity (130-fold lower). Its participation in detoxification of cyanide may be small. May be involved in the enhancement of serine sensitivity. Probable 3-mercaptopyruvate sulfurtransferase (EC 2.8.1.2) (Rhodanese- like protein) (MST). InterPro: Rhodanese/cdc25 fold; High confidence in function and specificity.
   
 0.625
azo0847
RND efflux transporter, permease protein; AcrB/AcrD/AcrF family. Members of this family are integral membrane proteins. Some are involved in drug resistance. AcrB cooperates with a membrane fusion protein, AcrA, and an outer membrane channel TolC. The structure shows the AcrB forms a homotrimer, TREMBL:Q9A7D5 (35% identity); TREMBL:Q9HXW4 (55% identity). Pfam (PF00873): AcrB/AcrD/AcrF family. TIGRFAM (TIGR00914): Heavy metal efflux pump, CzcA family. TIGRFAM (TIGR00915): Hydrophobe/Amphiphile Efflux-1 (HAE1) Family protein. TMHMM predicting 12 transmembrane helices. TC (2.A.6.2): The ( [...]
       0.603
Your Current Organism:
Azoarcus sp. BH72
NCBI taxonomy Id: 62928
Other names: A. sp. BH72
Server load: low (14%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.