STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
azo0899Hypothetical membrane protein. No good homology to a protein of similar size of the data bank. Pfam: FHA domain (PF00498). The forkhead-associated (FHA) domain is a putative nuclear signalling domain found in a variety of otherwise unrelated proteins. The FHA domain comprise approximately 55 to 75 amino acids and contains three highly conserved blocks separated by divergent spacer regions.To date, genes encoding FHA-containing proteins have been identified in eubacterial and eukaryotic but not archaeal genomes. The domain is present in a diverse range of proteins, such as kinases, phos [...] (173 aa)    
Predicted Functional Partners:
azo0898
Putative serine/threonine protein kinase,; Family membership.
 
 
   0.958
odhA
Probable 2-oxoglutarate dehydrogenase. Homology to odhA of A. eutrophus of 63% (sprot|ODO1_ALCEU). THE 2-OXOGLUTARATE DEHYDROGENASE COMPLEX CATALYZES THE OVERALL CONVERSION OF 2-OXOGLUTARATE TO SUCCINYL-COA & CO(2). IT CONTAINS MULTIPLE COPIES OF 3 ENZYMATIC COMPONENTS: 2-OXOGLUTARATE DEHYDROGENASE (E1) DIHYDROLIPOAMIDE SUCCINYLTRANSFERASE (E2) AND LIPOAMIDE DEHYDROGENASE (E3). InterPro: Dehydrogenase E1 component (IPR001017); Transletolase (IPR005474) Tigrfam: 2oxo_dh_E1: 2-oxoglutarate dehydrogenase, E1 component Pfam: Dehydrogenase E1 component, Transketolas, pyridine binding domain [...]
  
 
 
 0.844
azo3908
PutativeSerine/threonine-protein kinase (EC 2.7.11.1) (NimA-related protein kinase 4) (Serine/threonine protein kinase 2). Seems to act exclusively upon threonine residues. Pfam: Protein kinase domain; Family membership.
 
 
   0.804
azo3774
Putative serine/threonine-protein kinase (EC 2.7.11.1). Pfam: Protein kinase domain; Family membership.
 
 
   0.799
azo0988
Putative serine/threonine protein kinase,; Family membership.
 
 
 
 0.782
yloP
Putative serine/threonine kinase,; Family membership.
 
 
 
 0.782
azo1256
Putative serin/threonine protein kinase, only very low similarity to SWISSPROT: sprot|PKSC_STRCO (13% Streptomyces coelicolor, serine/threonine protein kinase PksC (EC 2.7.11.1)) / TREMBL: trembl|Q9S478 (13% Myxococcus xanthus, Pkn4). Pfam: PF00069 Pkinase. SMART:SM00221 STYKc (Protein kinase; unclassified specificity). SM00065 GAF (Domain present in phytochromes and cGMP-specific phosphodiesterases); Family membership.
 
 0.750
azo2450
Putative two-component system sensor protein,; Function unclear.
  
 
 0.749
azo3073
Hypothetical protein. No homology to the data base. Pfam: Protein tyrosine kinase, Protein kinase domain. Interpro: IPR000719 Protein kinase, IPR002290 Serine/threonine protein kinase, IPR001245 Tyrosine protein kinase, IPR011009 Protein kinase-like. No signal peptide. No TMHs.
  
 
   0.746
azo1323
Probable protein kinase InterPro: Protein kinase,Protein kinase-like.
 
 
   0.745
Your Current Organism:
Azoarcus sp. BH72
NCBI taxonomy Id: 62928
Other names: A. sp. BH72
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