STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
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Cooccurrence
Coexpression
Experiments
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[Homology]
Score
yccAProbable carrier/transport protein; Hypothetical protein PA2604. pir:D85624: 57% identity.73% similarity SIMILARITY:Belongs to the BI1 family. InterPro:Uncharacterized protein family UPF0005 IPR006213; Bax_inhbtr1. IPR006214; UPF0005. Pfam:ZIP: Zinc transporter Probable glutamatereceptor Signal peptide present (SignalP predicted) and transmembrane helices 7 (TMHMM predicted) Pfam:PF01027; UPF0005; InterPro: Uncharacterized protein family UPF0005 2_A_01_02: Multidrug resistance protein; Specificity unclear. (221 aa)    
Predicted Functional Partners:
azo0910
Conserved hypothetical protein. Homology to ebD81 Azoarcus sp. EbN1 of 64% (gnl|keqq|eba:ebD81(KEGG)). No domains predicted. No signal peptid. No TMHs.
  
    0.633
azo0839
SWI/SNF family helicase Pfam: Helicase conserved C-terminal domain; Specificity unclear.
    
 0.619
htpX
Putative protease HtpX Homolog to htpX of E. coli of 30% (AAA62779) InterPro: Peptidase family M48 (IPR001915) Pfam: Peptidase family M48 signal peptide TMHs3; Family membership; Belongs to the peptidase M48B family.
  
  
 0.547
omlA
Putative outer membrane lipoprotein OmlA; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.
  
    0.514
azo1494
Similarity to hypothetical protein in C. violaceum.
     
  0.512
smc
Chromosome segregation protein; Required for chromosome condensation and partitioning. Belongs to the SMC family.
     
  0.512
rosB
Putative Potassium/proton antiporter; Probable potassium antiporter, rosB. 38% HPr_SerP_S.IPR004771; K_eff.IPR006153; Na_H_porter. IPR003148; TrkA_N. Pfam:PF00999; Na_H_Exchanger; 1.PF02254; TrkA_N; 1. TIGRFAMs:TIGR00932; 2a37; 1. TMhelix: 12; High confidence in function and specificity; Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2.A.37) family.
       0.480
azo0081
Conserved hypothetical membrane protein. Homology to pa4965 ao P. aeruginosa of 50% (trembl|Q9HUK0) Pfam: Retroviral aspartyl protease no signal peptide 1 TMHs; Conserved hypothetical protein.
  
     0.449
gor
Probable glutathione-disulfide reductase. Homology to gor of E. coli of 53% (sprot|GSHR_ECOLI). Maintain high levels of reduced glutathione in the cytosol. InterPro: FAD-dependent pyridine nucleotide-disulphide oxidoreductase (IPR001327); NAD binding site (IPR000205); Pyridine nuclotide-disulfide oxidoreductase dimerisation doamin (IPR004099); Pyridine nucleotide-disulphide oxidoreductase, class I (IPR001100) Pfam: Pyridine nuccleotide-dusulfphide oxidoreductase; Pyridine nucleotide-disulphide oxidoreductase dimerisation domain no signal peptide no TMHs; High confidence in function and [...]
   
   0.421
azo1318
Conserved hypothetical membrane protein. Homology to RS04440 of Ralstonia solanacearum of 40% (trembl|Q8Y277) TMHMM2 reporting 2 TMH's present. Signal peptide Present. Has PF04280;Tim44-like domain(IPR007379):Tim44 is an essential component of the machinery that mediates the translocation of nuclear-encoded proteins across the mitochondrial inner membrane. Tim44 is thought to bind phospholipids of the mitochondrial inner membrane both by electrostatic interactions and by penetrating the polar head group region. This family includes the C-terminal region of Tim44 that has been shown to [...]
   
  
 0.414
Your Current Organism:
Azoarcus sp. BH72
NCBI taxonomy Id: 62928
Other names: A. sp. BH72
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