STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
rosBPutative Potassium/proton antiporter; Probable potassium antiporter, rosB. 38% HPr_SerP_S.IPR004771; K_eff.IPR006153; Na_H_porter. IPR003148; TrkA_N. Pfam:PF00999; Na_H_Exchanger; 1.PF02254; TrkA_N; 1. TIGRFAMs:TIGR00932; 2a37; 1. TMhelix: 12; High confidence in function and specificity; Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2.A.37) family. (573 aa)    
Predicted Functional Partners:
kefB
Glutathione-regulated potassium-efflux system protein kefB,(K+/H+ antiporter).Transport system that facilitates potassium-efflux possibly by potassium-proton antiport. 32% K_eff.IPR006153; Na_H_porter.IPR006036;TrkA_Kuptake. IPR003148; TrkA_N. Pfam:PF00999; Na_H_Exchanger; 1.PF02254; TrkA-N; 1. TIGRFAMs:TIGR00932; 2a37; 1. TMHelix:12. Belongs to the monovalent cation:proton antiporter 2 (cpa2) transporter (TC 2.A.37) family. KefB subfamily; High confidence in function and specificity.
 
   
0.669
azo0482
Conserved hypothetical membrane protein. Homology to yqaA of Nitrosomonas europaea of 50% (trembl|Q82TH7(SRS)) No domains predicted. Signal peptide present. TMHMM2 reporting presence of 2 TMH's; Conserved hypothetical protein.
  
    0.659
azo0795
Probable glutathione-regulated potassium-efflux system protein (K(+)/H(+) antiporter). Transport system that facilitate potassium-efflux possibly by potassium-proton antiport. 50% Na_H_porter.IPR006037; TrkAC.IPR003148; TrkA_N. Pfam: PF00999; Na_H_Exchanger; 1.PF02080; TrkA_C; 1.PF02254; TrkA_N; 1. TMhelix: 11; High confidence in function and specificity; Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2.A.37) family.
 
   
0.655
kup
Putative potassium uptake protein; Transport of potassium into the cell; Belongs to the HAK/KUP transporter (TC 2.A.72) family.
 
   
 0.524
flgG
Flagellar basal-body rod protein flgG (Distal rod protein). The rod has been shown to consist of four different, yet evolutionary related proteins: in the distal portion of the rod there are about 26 subunits of protein flgG and in the proximal portion there are about six subunits each of proteins flgB, flgC, and flgF. These four proteins contain a highly conserved asparagine-rich domain at their N terminus. InterPro: Flagella basal body rod protein no signal peptide no TMHs; High confidence in function and specificity.
    
   0.491
yccA
Probable carrier/transport protein; Hypothetical protein PA2604. pir:D85624: 57% identity.73% similarity SIMILARITY:Belongs to the BI1 family. InterPro:Uncharacterized protein family UPF0005 IPR006213; Bax_inhbtr1. IPR006214; UPF0005. Pfam:ZIP: Zinc transporter Probable glutamatereceptor Signal peptide present (SignalP predicted) and transmembrane helices 7 (TMHMM predicted) Pfam:PF01027; UPF0005; InterPro: Uncharacterized protein family UPF0005 2_A_01_02: Multidrug resistance protein; Specificity unclear.
       0.480
ribAB
GTP cyclohydrolase II; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; Belongs to the DHBP synthase family.
   
   0.436
azo0910
Conserved hypothetical protein. Homology to ebD81 Azoarcus sp. EbN1 of 64% (gnl|keqq|eba:ebD81(KEGG)). No domains predicted. No signal peptid. No TMHs.
  
    0.431
mscL
Large-conductance mechanosensitive channel; Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell.
      
 0.426
azo3915
Putative Na/H(+) antiporter; 23% K_eff.IPR006153; Na_H_porter. Pfam:PF00999; Na_H_Exchanger; 1. TIGRFAMs:TIGR00932; 2a37; 1. TMHelix: 11; High confidence in function and specificity.
 
   
 0.417
Your Current Organism:
Azoarcus sp. BH72
NCBI taxonomy Id: 62928
Other names: A. sp. BH72
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