STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
dedADedA family protein, 57% identity(75% similarity) to TrEMBL;Q88QF4. TrEMBl;Q889M5(57% identity). SwissProt;P09548(55% identity) Has PF00597, DedA family;IPR000252;This family combines the DedA related proteins and YIAN/YGIK family. Members of this family are not functionally characterised. These proteins contain multiple predicted transmembrane regions; High confidence in function and specificity. (215 aa)    
Predicted Functional Partners:
flgC
Flagellar basal-body rod protein flgC. The rod has been shown to consist of four different, yet evolutionary related proteins: in the distal portion of the rod there are about 26 subunits of protein flgG and in the proximal portion there are about six subunits each of proteins flgB, flgC, and flgF. These four proteins contain a highly conserved asparagine-rich domain at their N terminus. InterPro: Flagella basal body rod protein no signal peptide no TMHs; High confidence in function and specificity.
    
   0.612
ndk
Nucleoside-diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family.
       0.543
dctM2
Putative TRAP-type C4-dicarboxylate transport system, large permease; The dct locus encodes a high-affinity transport system for the C4-dicarboxylates malate,succinate, and fumarate. 60% DctM.IPR000252; DedA.IPR004681; TRAP_transptDctM. Pfam:PF06808; DctM; 1.PF00597; DedA; 1. TIGRFAMs:TIGR00786; dctM; 1. TMhelix:13. Signal peptide: present; High confidence in function and specificity.
       0.475
azo1685
Conserved hypothetical protein. Homology to NE0619 of Nitrosomonas europaea of 44% (trembl:Q82WP5). Has PF06167, IPR010384; Protein of unknown function (DUF980);Family of uncharacterised bacterial sequences. No signal peptide. No TMHs; Belongs to the MtfA family.
  
  
 0.470
dctQ2
Putative TRAP-type C4-dicarboxylate transport system, small permease; The dct locus encodes a high-affinity transport system for the C4-dicarboxylates malate,succinate, and fumarate. 45% DctQ. Pfam:PF04290; DctQ; 1. TMhelix:4; High confidence in function and specificity.
       0.455
bamB
Conserved hypothetical protein; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.
     
 0.451
macB
ATP-binding/permease fusion ABC transporter; Non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the inner membrane, and an ATP- binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides.
 
    0.438
rlmN
Conserved hypothetical protein; Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs. m2A2503 modification seems to play a crucial role in the proofreading step occurring at the peptidyl transferase center and thus would serve to optimize ribosomal fidelity; Belongs to the radical SAM superfamily. RlmN family.
       0.416
azo0833
ATP-binding cassette (ABC) transporters form a large family of proteins responsible for translocation of a variety of compounds across biological membranes. They are composed of two transmembrane domains responsible for binding and transport and two nucleotide-binding domains responsible for coupling the energy of ATP hydrolysis to conformational changes in the TMDs, TREMBL:Q8YZK5 (28% identity); TREMBL:Q8DJ46 (29% identity). Pfam (DUF214): Predicted permease. TMHMM reporting five transmembrane helices. TC (3.A.1.122.): The Macrolide Exporter (MacB) Family; Specificity unclear.
  
    0.415
azo0929
Conserved hypothetical protein; Putative membrane protein, 32% identity to TrEMBL;Q7WHN2. Signal Peptide present; Specificity unclear.
     
 0.411
Your Current Organism:
Azoarcus sp. BH72
NCBI taxonomy Id: 62928
Other names: A. sp. BH72
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