node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
aroA | azo2110 | azo1071 | azo2110 | 3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate; Belongs to the cytidylate kinase family. Type 1 subfamily. | Pseudouridylate synthase; Conserved hypothetical protein; Family membership; Belongs to the pseudouridine synthase RsuA family. | 0.706 |
aroA | engA | azo1071 | azo0931 | 3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate; Belongs to the cytidylate kinase family. Type 1 subfamily. | Probable GTP-binding protein; GTPase that plays an essential role in the late steps of ribosome biogenesis; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family. | 0.842 |
aroA | ffh | azo1071 | azo3232 | 3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate; Belongs to the cytidylate kinase family. Type 1 subfamily. | Signal recognition particle protein; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual componen [...] | 0.662 |
aroA | gpsA | azo1071 | azo2814 | 3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate; Belongs to the cytidylate kinase family. Type 1 subfamily. | Probable NAD-dependent glycerol-3-phosphate dehydrogenase [NAD(P)+]. Homology to gpsA of B. subtilis of 41% (SWISSPROT:GPDA_BACSU). NAD-dependent glycerol-3-phosphate dehydrogenase catalyzes the reversible reduction of dihydroxyacetone phosphate to glycerol-3-phosphate. InterPro: NAD-dependent glycerol-3-phosphate dehydrogenase (IPR006109) Pfam: NAD-dependent glycerol-3-phosphate dehydrogeanse signal peptide no TMHs apbA_panE: 2-dehydropantoate 2-reductas; High confidence in function and specificity. | 0.598 |
azo0929 | bamB | azo0929 | azo0930 | Conserved hypothetical protein; Putative membrane protein, 32% identity to TrEMBL;Q7WHN2. Signal Peptide present; Specificity unclear. | Conserved hypothetical protein; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane. | 0.979 |
azo0929 | engA | azo0929 | azo0931 | Conserved hypothetical protein; Putative membrane protein, 32% identity to TrEMBL;Q7WHN2. Signal Peptide present; Specificity unclear. | Probable GTP-binding protein; GTPase that plays an essential role in the late steps of ribosome biogenesis; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family. | 0.862 |
azo0929 | hisS | azo0929 | azo0928 | Conserved hypothetical protein; Putative membrane protein, 32% identity to TrEMBL;Q7WHN2. Signal Peptide present; Specificity unclear. | Histidine--tRNA ligase; Histidyl-tRNA synthetase. hisS, 75% idemtity to TrEMBL;Q5P7B4. Has Pfam;PF00587, tRNA synthetase class II core domain (G, H, P, S and T).Other tRNA synthetase sub-families are too disIPR002314,tRNA-synt_2b. Has Pfam;PF03129,Anticodon binding domain. This domain is found in histidyl, glycyl, threonyl and prolyl tRNA synthetases it is probably the anticodon binding domain; High confidence in function and specificity. | 0.969 |
azo0929 | rlmN | azo0929 | azo0924 | Conserved hypothetical protein; Putative membrane protein, 32% identity to TrEMBL;Q7WHN2. Signal Peptide present; Specificity unclear. | Conserved hypothetical protein; Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs. m2A2503 modification seems to play a crucial role in the proofreading step occurring at the peptidyl transferase center and thus would serve to optimize ribosomal fidelity; Belongs to the radical SAM superfamily. RlmN family. | 0.725 |
azo2110 | aroA | azo2110 | azo1071 | Pseudouridylate synthase; Conserved hypothetical protein; Family membership; Belongs to the pseudouridine synthase RsuA family. | 3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate; Belongs to the cytidylate kinase family. Type 1 subfamily. | 0.706 |
azo2110 | engA | azo2110 | azo0931 | Pseudouridylate synthase; Conserved hypothetical protein; Family membership; Belongs to the pseudouridine synthase RsuA family. | Probable GTP-binding protein; GTPase that plays an essential role in the late steps of ribosome biogenesis; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family. | 0.803 |
azo2110 | rlmN | azo2110 | azo0924 | Pseudouridylate synthase; Conserved hypothetical protein; Family membership; Belongs to the pseudouridine synthase RsuA family. | Conserved hypothetical protein; Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs. m2A2503 modification seems to play a crucial role in the proofreading step occurring at the peptidyl transferase center and thus would serve to optimize ribosomal fidelity; Belongs to the radical SAM superfamily. RlmN family. | 0.487 |
bamB | azo0929 | azo0930 | azo0929 | Conserved hypothetical protein; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane. | Conserved hypothetical protein; Putative membrane protein, 32% identity to TrEMBL;Q7WHN2. Signal Peptide present; Specificity unclear. | 0.979 |
bamB | engA | azo0930 | azo0931 | Conserved hypothetical protein; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane. | Probable GTP-binding protein; GTPase that plays an essential role in the late steps of ribosome biogenesis; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family. | 0.844 |
bamB | hisS | azo0930 | azo0928 | Conserved hypothetical protein; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane. | Histidine--tRNA ligase; Histidyl-tRNA synthetase. hisS, 75% idemtity to TrEMBL;Q5P7B4. Has Pfam;PF00587, tRNA synthetase class II core domain (G, H, P, S and T).Other tRNA synthetase sub-families are too disIPR002314,tRNA-synt_2b. Has Pfam;PF03129,Anticodon binding domain. This domain is found in histidyl, glycyl, threonyl and prolyl tRNA synthetases it is probably the anticodon binding domain; High confidence in function and specificity. | 0.909 |
bamB | rlmN | azo0930 | azo0924 | Conserved hypothetical protein; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane. | Conserved hypothetical protein; Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs. m2A2503 modification seems to play a crucial role in the proofreading step occurring at the peptidyl transferase center and thus would serve to optimize ribosomal fidelity; Belongs to the radical SAM superfamily. RlmN family. | 0.714 |
dnaG | engA | azo3226 | azo0931 | DNA primase; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. | Probable GTP-binding protein; GTPase that plays an essential role in the late steps of ribosome biogenesis; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family. | 0.878 |
dnaG | secA | azo3226 | azo0893 | DNA primase; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. | Preprotein translocase SecA subunit; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane. Belongs to the SecA family. | 0.649 |
engA | aroA | azo0931 | azo1071 | Probable GTP-binding protein; GTPase that plays an essential role in the late steps of ribosome biogenesis; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family. | 3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate; Belongs to the cytidylate kinase family. Type 1 subfamily. | 0.842 |
engA | azo0929 | azo0931 | azo0929 | Probable GTP-binding protein; GTPase that plays an essential role in the late steps of ribosome biogenesis; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family. | Conserved hypothetical protein; Putative membrane protein, 32% identity to TrEMBL;Q7WHN2. Signal Peptide present; Specificity unclear. | 0.862 |
engA | azo2110 | azo0931 | azo2110 | Probable GTP-binding protein; GTPase that plays an essential role in the late steps of ribosome biogenesis; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family. | Pseudouridylate synthase; Conserved hypothetical protein; Family membership; Belongs to the pseudouridine synthase RsuA family. | 0.803 |