STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
engAProbable GTP-binding protein; GTPase that plays an essential role in the late steps of ribosome biogenesis; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family. (442 aa)    
Predicted Functional Partners:
gpsA
Probable NAD-dependent glycerol-3-phosphate dehydrogenase [NAD(P)+]. Homology to gpsA of B. subtilis of 41% (SWISSPROT:GPDA_BACSU). NAD-dependent glycerol-3-phosphate dehydrogenase catalyzes the reversible reduction of dihydroxyacetone phosphate to glycerol-3-phosphate. InterPro: NAD-dependent glycerol-3-phosphate dehydrogenase (IPR006109) Pfam: NAD-dependent glycerol-3-phosphate dehydrogeanse signal peptide no TMHs apbA_panE: 2-dehydropantoate 2-reductas; High confidence in function and specificity.
  
 0.943
dnaG
DNA primase; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.
   
  
 0.878
azo0929
Conserved hypothetical protein; Putative membrane protein, 32% identity to TrEMBL;Q7WHN2. Signal Peptide present; Specificity unclear.
 
    0.862
bamB
Conserved hypothetical protein; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.
  
  
 0.844
hisS
Histidine--tRNA ligase; Histidyl-tRNA synthetase. hisS, 75% idemtity to TrEMBL;Q5P7B4. Has Pfam;PF00587, tRNA synthetase class II core domain (G, H, P, S and T).Other tRNA synthetase sub-families are too disIPR002314,tRNA-synt_2b. Has Pfam;PF03129,Anticodon binding domain. This domain is found in histidyl, glycyl, threonyl and prolyl tRNA synthetases it is probably the anticodon binding domain; High confidence in function and specificity.
 
  
 0.842
aroA
3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate; Belongs to the cytidylate kinase family. Type 1 subfamily.
  
 0.842
secA
Preprotein translocase SecA subunit; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane. Belongs to the SecA family.
 
  
 0.816
azo2110
Pseudouridylate synthase; Conserved hypothetical protein; Family membership; Belongs to the pseudouridine synthase RsuA family.
 
  
 0.803
rlmN
Conserved hypothetical protein; Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs. m2A2503 modification seems to play a crucial role in the proofreading step occurring at the peptidyl transferase center and thus would serve to optimize ribosomal fidelity; Belongs to the radical SAM superfamily. RlmN family.
 
     0.802
ffh
Signal recognition particle protein; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual componen [...]
 
  
 0.767
Your Current Organism:
Azoarcus sp. BH72
NCBI taxonomy Id: 62928
Other names: A. sp. BH72
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