| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| engB | rlmB | azo2822 | azo0940 | Conserved hypothetical GTP-binding protein; Necessary for normal cell division and for the maintenance of normal septation; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family. | tRNA/rRNA methyltransferase; Specifically methylates the ribose of guanosine 2251 in 23S rRNA. | 0.906 |
| engB | rplC | azo2822 | azo3417 | Conserved hypothetical GTP-binding protein; Necessary for normal cell division and for the maintenance of normal septation; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family. | 50S ribosomal protein L3; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit. | 0.905 |
| engB | rplK | azo2822 | azo3428 | Conserved hypothetical GTP-binding protein; Necessary for normal cell division and for the maintenance of normal septation; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family. | 50S ribosomal protein L11; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. | 0.890 |
| engB | rplM | azo2822 | azo2760 | Conserved hypothetical GTP-binding protein; Necessary for normal cell division and for the maintenance of normal septation; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family. | 50S ribosomal protein L13; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly. | 0.889 |
| engB | rplO | azo2822 | azo3398 | Conserved hypothetical GTP-binding protein; Necessary for normal cell division and for the maintenance of normal septation; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family. | 50S ribosomal protein L15; Binds to the 23S rRNA; Belongs to the universal ribosomal protein uL15 family. | 0.913 |
| engB | rplU | azo2822 | azo3167 | Conserved hypothetical GTP-binding protein; Necessary for normal cell division and for the maintenance of normal septation; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family. | 50S ribosomal protein L21; This protein binds to 23S rRNA in the presence of protein L20; Belongs to the bacterial ribosomal protein bL21 family. | 0.912 |
| engB | rsfS | azo2822 | azo3608 | Conserved hypothetical GTP-binding protein; Necessary for normal cell division and for the maintenance of normal septation; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family. | Conserved hypothetical protein; Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation. | 0.902 |
| engB | thdF | azo2822 | azo3988 | Conserved hypothetical GTP-binding protein; Necessary for normal cell division and for the maintenance of normal septation; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family. | Probable tRNA modification GTPase; Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family. | 0.942 |
| engB | ylqF | azo2822 | azo2120 | Conserved hypothetical GTP-binding protein; Necessary for normal cell division and for the maintenance of normal septation; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family. | Probable GTPase; Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity; Belongs to the TRAFAC class YlqF/YawG GTPase family. MTG1 subfamily. | 0.927 |
| rlmB | engB | azo0940 | azo2822 | tRNA/rRNA methyltransferase; Specifically methylates the ribose of guanosine 2251 in 23S rRNA. | Conserved hypothetical GTP-binding protein; Necessary for normal cell division and for the maintenance of normal septation; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family. | 0.906 |
| rlmB | rplC | azo0940 | azo3417 | tRNA/rRNA methyltransferase; Specifically methylates the ribose of guanosine 2251 in 23S rRNA. | 50S ribosomal protein L3; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit. | 0.879 |
| rlmB | rplK | azo0940 | azo3428 | tRNA/rRNA methyltransferase; Specifically methylates the ribose of guanosine 2251 in 23S rRNA. | 50S ribosomal protein L11; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. | 0.916 |
| rlmB | rplM | azo0940 | azo2760 | tRNA/rRNA methyltransferase; Specifically methylates the ribose of guanosine 2251 in 23S rRNA. | 50S ribosomal protein L13; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly. | 0.902 |
| rlmB | rplO | azo0940 | azo3398 | tRNA/rRNA methyltransferase; Specifically methylates the ribose of guanosine 2251 in 23S rRNA. | 50S ribosomal protein L15; Binds to the 23S rRNA; Belongs to the universal ribosomal protein uL15 family. | 0.877 |
| rlmB | rplU | azo0940 | azo3167 | tRNA/rRNA methyltransferase; Specifically methylates the ribose of guanosine 2251 in 23S rRNA. | 50S ribosomal protein L21; This protein binds to 23S rRNA in the presence of protein L20; Belongs to the bacterial ribosomal protein bL21 family. | 0.879 |
| rlmB | rsfS | azo0940 | azo3608 | tRNA/rRNA methyltransferase; Specifically methylates the ribose of guanosine 2251 in 23S rRNA. | Conserved hypothetical protein; Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation. | 0.882 |
| rlmB | thdF | azo0940 | azo3988 | tRNA/rRNA methyltransferase; Specifically methylates the ribose of guanosine 2251 in 23S rRNA. | Probable tRNA modification GTPase; Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family. | 0.903 |
| rlmB | vacB | azo0940 | azo0939 | tRNA/rRNA methyltransferase; Specifically methylates the ribose of guanosine 2251 in 23S rRNA. | Exoribonuclease II; 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs. | 0.937 |
| rlmB | ylqF | azo0940 | azo2120 | tRNA/rRNA methyltransferase; Specifically methylates the ribose of guanosine 2251 in 23S rRNA. | Probable GTPase; Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity; Belongs to the TRAFAC class YlqF/YawG GTPase family. MTG1 subfamily. | 0.912 |
| rplC | engB | azo3417 | azo2822 | 50S ribosomal protein L3; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit. | Conserved hypothetical GTP-binding protein; Necessary for normal cell division and for the maintenance of normal septation; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family. | 0.905 |