Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
nasENitrate transport permease protein nasE. 41% Similar to the nitrate permease protein, nrtB in Synechococcus sp.Part of the ABC transporter complex nrtBCD involved in nitrate import.Probably responsible for the translocation of the substrate across the membrane. SWISSPROT:NRTB_SYNP7.P38044. InterPro:IPR000515; BPD_transp.IPR005889; NtrB. Pfam:PF00528; BPD_transp; 1. TIGRFAMs:TIGR01183; ntrB; 1. TMHelix: 4; High confidence in function and specificity. (310 aa)    
Predicted Functional Partners:
nasF
Nitrate transport system, periplasmic-binding protein; Part of the ABC transporter complex NasFED involved in nitrate import. 59% Similar to the putative periplasmic-binding protein NasF in Klebsiella oxytoca. TREMBL:Q48466 InterPro:IPR010067; SsuA_fam.IPR006311; Tat. TIGRFAMs:TIGR01728; SsuA_fam; 1.TIGR01409; TAT_signal_seq; 1. Signal peptide present; High confidence in function and specificity.
 
 0.998
nasD
Putative nitrate transport system, ATP-binding protein; Part of the ABC transporter complex nasFED involved in nitrate import. 64% Similar to the nitrate transport membrane protein, nasD in Klebsella oxytoca. Probably responsible for energy coupling to the transport system. SWISSPROT:NASD_KLEOX.P39459. InterPro:IPR003593; AAA_ATPase.IPR003439; ABC_transporter.IPR005890; NtrCD. Pfam:PF00005; ABC_tran; 1. TIGRFAMs:TIGR01184; ntrCD; 1; High confidence in function and specificity.
 0.998
tauB
Putative sulfonate transport system, ATP-binding protein; Part of the ABC transporter complex tauABC involved in taurine import as a sulfur source.Probably responsible for energy coupling to the transport system.Similar to the aliphatic sulfonate transport membrane protein, tauB in E.coli. Probably also involved in nitrate and bicarbonate transport; High confidence in function and specificity.
 
 0.970
azo3513
Putative aliphatic sulfonates transport system,ATP-binding protein; Region start changed from 3855391 to 3855571 (-180 bases).
 
 0.959
tauA
Putative sulfonate transport system, periplasmic component; Part of the ABC transporter complex tauABC involved in taurine as a sulfur source import. Similar to the putative aliphatic sulfonates periplasmic-binding protein tauA in E.coli. Probably also involved in nitrate and bicarbonate transport; Function unclear.
 
 0.953
azo3384
Putative aliphatic sulfonates binding protein precursor.PART OF A BINDING-PROTEIN-DEPENDENT TRANSPORT SYSTEM FOR ALIPHATIC SULFONATES. PUTATIVE BINDING PROTEIN. 22% SBP_bac_3. SMART: SM00062; PBPb; 1; Specificity unclear.
 
 0.877
ssuA
Putative periplasmic-binding protein; Part of the ABC transporter complex ssuABC involved in aliphatic sulfonates import.Similar to the putative periplasmic-binding protein ssuA precursor in E.coli. SSUA_BACSU:P40400. InterPro:IPR000437; Prok_lipoprot_S. IPR001638; SBP_bac_3. SMART: SM00062; PBPb; 1. TMhelix:1. Signal peptide: present; Specificity unclear.
 
 0.868
nasA
Probable Nitrate reductase. Homology to nasA of K. oxytoca of 41% (sprot|NASA_KLEOX). Nitrate reductase is a key enzyme involved in the first step of nitrate assimilation in plants fungi and bacteria. InterPro: Prokaryotic molybdopterin oxidoreductases (IPR006655) Pfam: Molybdopterin oxidoreductase; Molydopterin dinucleotide binding domain no signal peptide no TMH Helixturnhelix motif; High confidence in function and specificity; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. NasA/NapA/NarB subfamily.
 
  
 0.822
nasC
Putative nitrate reducatse small subunit. Homology to nasC of K. oxytoca of 38% (trembl|Q48467). NasC probably mediates electron transfer from NADH to NasA, the nitrate reductase. InterPro: FAD-dependent pyridine nucleotide-disulphide oxidoreductase (IPR001327) Pfam: Pyridine nucleotide-disulfide oxidoreductase no signal peptide no TMHs; Family membership.
 
  
 0.624
azo1944
Conserved hypothetical protein. Homology to mll3445) of M. loti of 71% (trembl|Q98G8). InterPro: Bacterial luciferase (IPR002103). Pfam: Luciferase-like monooxygenase. no signal peptide. no TMHS.
  
 
 0.605
Your Current Organism:
Azoarcus sp. BH72
NCBI taxonomy Id: 62928
Other names: A. sp. BH72
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