STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
nasCPutative nitrate reducatse small subunit. Homology to nasC of K. oxytoca of 38% (trembl|Q48467). NasC probably mediates electron transfer from NADH to NasA, the nitrate reductase. InterPro: FAD-dependent pyridine nucleotide-disulphide oxidoreductase (IPR001327) Pfam: Pyridine nucleotide-disulfide oxidoreductase no signal peptide no TMHs; Family membership. (415 aa)    
Predicted Functional Partners:
nasA
Probable Nitrate reductase. Homology to nasA of K. oxytoca of 41% (sprot|NASA_KLEOX). Nitrate reductase is a key enzyme involved in the first step of nitrate assimilation in plants fungi and bacteria. InterPro: Prokaryotic molybdopterin oxidoreductases (IPR006655) Pfam: Molybdopterin oxidoreductase; Molydopterin dinucleotide binding domain no signal peptide no TMH Helixturnhelix motif; High confidence in function and specificity; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. NasA/NapA/NarB subfamily.
 
 0.996
nirD
Nitrite reductase [NAD(P)H] small subunit (EC 1.7.1.4). REQUIRED FOR ACTIVITY OF THE REDUCTASE. 66% simialr to the nirD protein from R. solanacearum,a probable nitrite reductase NADPH (small subunit) oxidoreductase protein [EC:1.7.1.4]. TREMBL:Q8XQK3. InterPro: Rieske iron-sulfur protein 2Fe-2S subunit In E.coli, the NADH-dependent nitrite reductase catalyzes the six-electron reduction of nitrite to ammonia and also catalyzes the two-electron reduction of hydroxylamine to ammonia. The enzyme is a FAD-flavoprotein, and also contains a siroheme and one 2Fe-2S center; Conserved hypothetic [...]
 0.963
nagAb
Putative ferredoxin; Naphthalene 12-dioxygenase system ferredoxin component. COMPONENT OF NAPHTHALENE DIOXYGENASE (NDO) MULTICOMPONENT ENZYME SYSTEM WHICH CATALYZES THE INCORPORATION OF BOTH ATOMS OF MOLECULAR OXYGEN INTO NAPHTHALENE TO FORM CIS- NAPHTHALENE DIHYDRODIOL. THIS SUBUNIT IS A 2FE-2S FERREDOXIN THAT TRANSFERS ELECTRONS TO IRON SULFUR PROTEIN COMPONENTS (ISP); High confidence in function and specificity.
 
 0.944
rubB
RubB protein; High confidence in function and specificity.
  
 0.910
azo2601
Ferredoxin subunits of nitrite reductase. THIS SUBUNIT IS A 2FE-2S FERREDOXIN THAT TRANSFERS ELECTRONS TO IRON SULFUR PROTEIN COMPONENTS (ISP). Similar to nasE,from S.aureus_N315 a naphthalene 12-dioxygenase system ferredoxin component; High confidence in function and specificity.
 
 0.868
napA1
Nitrate reductase; Catalytic subunit of the periplasmic nitrate reductase complex NapAB. Receives electrons from NapB and catalyzes the reduction of nitrate to nitrite.
  
 0.867
narK
Probable nitrate transporters are involved in excretion of nitrite produced by the dissimilatory reduction of nitrate. NarK is polytopic membrane protein with 12 transmembrane domains which is involved in nitrate uptake and nitrite excretion and is thought to function as a nitrate/nitrite antiporter. At low concentrations of nitrate, NarK mediates the electrogenic excretion of nitrite rather than nitrate/nitrite exchange., 90% similarity to a probable nitrate transporter protein in Azoarcus sp. EbN1., InterPRo:04737: nitrate transporter,Signal peptide no present, TMHx:12, ; High confid [...]
 
 
 0.856
rubA
Probable rubredoxin. Homology to ruba of A. calcoaceticus of 42% (sprot|RUBR_ACIAD). Involved in the hydrocarbon hydroxylating system to convert dodecane to lauric acid, which transfers electrons from NADH to rubredoxin reductase and then through rubredoxin to alkane 1 monooxygenase. Pfam: Rubredoxin no singal peptide no TMHs; Family membership.
  
 0.855
fprA
Probable type A flavoprotein fprA. Homology to frpA of R. capsulatus of 58% (sprot|FPRA_RHOCA) Low-potential electron donor to a number of redox enzymes (Potential). InterPro: Metallo-beta-lactamase superfamily (IPR001279); Flavodoxin (IPR001226) Pfam: Metallo-beta-lactamase superfamily; Flavodoxin no singal peptide no TMHs; Family membership.
 
  
 0.852
nasF
Nitrate transport system, periplasmic-binding protein; Part of the ABC transporter complex NasFED involved in nitrate import. 59% Similar to the putative periplasmic-binding protein NasF in Klebsiella oxytoca. TREMBL:Q48466 InterPro:IPR010067; SsuA_fam.IPR006311; Tat. TIGRFAMs:TIGR01728; SsuA_fam; 1.TIGR01409; TAT_signal_seq; 1. Signal peptide present; High confidence in function and specificity.
 
 
 0.845
Your Current Organism:
Azoarcus sp. BH72
NCBI taxonomy Id: 62928
Other names: A. sp. BH72
Server load: low (24%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.