| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| azo0952 | azo1252 | azo0952 | azo1252 | Conserved hypothetical protein, 38% identity (50% similarity) to TrEMBL;Q7WXG4 Signal Peptide Present.TMH not Present. Has PF04471:Restriction endonuclease;(IPR007560:Mrr_cat):Prokaryotic family found in type II restriction enzymes containing the hallmark (D/E)-(D/E)XK active site. Presence of catalytic residues implicates this region in the enzymatic cleavage of DNA. PF01396:Topoisomerase DNA binding C4 zinc finger;(IPR000380 DNA_tpisomrase):Prokaryotic topoisomerase I, otherwise known as relaxing enzyme,untwisting enzyme or swivelase, catalyses the ATP-independent breakage of single- [...] | Conserved hypothetical membrane protein. Homology to XCC3430 of Xanthomonas campestris of 38% (trembl:Q8P5B1). Has PF04892, VanZ like family;IPR006976; This family contains several examples of the VanZ protein,but also contains examples of phosphotransbutyrylases. VanZ confers low-level resistance to the glycopeptide antibiotic teicoplanin (Te). Analysis of cytoplasmic peptidoglycan precursors, accumulated in the presence of ramoplanin, showed that VanZ-mediated Te resistance does not involve incorporation of a substituent of D-alanine into the peptidoglycan precursors. no signal pepti [...] | 0.584 |
| azo0952 | azo2931 | azo0952 | azo2931 | Conserved hypothetical protein, 38% identity (50% similarity) to TrEMBL;Q7WXG4 Signal Peptide Present.TMH not Present. Has PF04471:Restriction endonuclease;(IPR007560:Mrr_cat):Prokaryotic family found in type II restriction enzymes containing the hallmark (D/E)-(D/E)XK active site. Presence of catalytic residues implicates this region in the enzymatic cleavage of DNA. PF01396:Topoisomerase DNA binding C4 zinc finger;(IPR000380 DNA_tpisomrase):Prokaryotic topoisomerase I, otherwise known as relaxing enzyme,untwisting enzyme or swivelase, catalyses the ATP-independent breakage of single- [...] | Conserved hypothetical protein. Homology to gsu0911 of G. sulfurreducens of 38% (tremblnew|AAR34238). Pfam: 4Fe-4S binding domain. no signal peptide. no TMHs. | 0.890 |
| azo0952 | fdhB | azo0952 | azo3481 | Conserved hypothetical protein, 38% identity (50% similarity) to TrEMBL;Q7WXG4 Signal Peptide Present.TMH not Present. Has PF04471:Restriction endonuclease;(IPR007560:Mrr_cat):Prokaryotic family found in type II restriction enzymes containing the hallmark (D/E)-(D/E)XK active site. Presence of catalytic residues implicates this region in the enzymatic cleavage of DNA. PF01396:Topoisomerase DNA binding C4 zinc finger;(IPR000380 DNA_tpisomrase):Prokaryotic topoisomerase I, otherwise known as relaxing enzyme,untwisting enzyme or swivelase, catalyses the ATP-independent breakage of single- [...] | Probable formate dehydrogenase iron-sulfur subunit. Homology to fdhB of W. succinogenes of 63% (SWISSPROT:FDHB_WOLSU) THIS CHAIN IS AN ELECTRON TRANSFER UNIT CONTAINING 18 CYSTEINE RESIDUES 16 OF WHICH OCCUR IN THREE CLUSTERS. InterPro: 4Fe-4S ferredoxin iron-sulfur binding domain (IPR001450); 7Fe ferredoxin (IPR000813); 3Fe-4S ferredoxin (IPR001080) Pfam: 4Fe-4S binding domain no signal peptide no TMHs; High confidence in function and specificity. | 0.890 |
| azo0952 | fldA | azo0952 | azo2544 | Conserved hypothetical protein, 38% identity (50% similarity) to TrEMBL;Q7WXG4 Signal Peptide Present.TMH not Present. Has PF04471:Restriction endonuclease;(IPR007560:Mrr_cat):Prokaryotic family found in type II restriction enzymes containing the hallmark (D/E)-(D/E)XK active site. Presence of catalytic residues implicates this region in the enzymatic cleavage of DNA. PF01396:Topoisomerase DNA binding C4 zinc finger;(IPR000380 DNA_tpisomrase):Prokaryotic topoisomerase I, otherwise known as relaxing enzyme,untwisting enzyme or swivelase, catalyses the ATP-independent breakage of single- [...] | Hypothetical protein FldA, 78% identity (86% similarity) to TrEMBL;Q6N0R5,Q8PF30(47% identity). 45% identity to ybhH of SwissProt;P75762(E.coli) Has PF04303,Protein of unknown function (DUF453);IPR007400; FldA (Q9L3A0) is thought to be involved in the degradation of the polyaromatic hydrocarbon fluorene by Sphingomonas sp. LB126. Has PF01678, Diaminopimelate epimerase;IPR001653 DAP_epimerase: Diaminopimelate epimerase contains two domains of the same alpha/beta fold, both contained in this family.Diaminopimelate epimerase (EC:5.1.1.7) catalyzes the isomeriazation of L,L- to D,L-meso-di [...] | 0.789 |
| azo0952 | leuS | azo0952 | azo3215 | Conserved hypothetical protein, 38% identity (50% similarity) to TrEMBL;Q7WXG4 Signal Peptide Present.TMH not Present. Has PF04471:Restriction endonuclease;(IPR007560:Mrr_cat):Prokaryotic family found in type II restriction enzymes containing the hallmark (D/E)-(D/E)XK active site. Presence of catalytic residues implicates this region in the enzymatic cleavage of DNA. PF01396:Topoisomerase DNA binding C4 zinc finger;(IPR000380 DNA_tpisomrase):Prokaryotic topoisomerase I, otherwise known as relaxing enzyme,untwisting enzyme or swivelase, catalyses the ATP-independent breakage of single- [...] | Leucine--tRNA ligase; Unnamed protein product; Region start changed from 3544790 to 3544922 (-132 bases); Belongs to the class-I aminoacyl-tRNA synthetase family. | 0.733 |
| azo0952 | ligA | azo0952 | azo2001 | Conserved hypothetical protein, 38% identity (50% similarity) to TrEMBL;Q7WXG4 Signal Peptide Present.TMH not Present. Has PF04471:Restriction endonuclease;(IPR007560:Mrr_cat):Prokaryotic family found in type II restriction enzymes containing the hallmark (D/E)-(D/E)XK active site. Presence of catalytic residues implicates this region in the enzymatic cleavage of DNA. PF01396:Topoisomerase DNA binding C4 zinc finger;(IPR000380 DNA_tpisomrase):Prokaryotic topoisomerase I, otherwise known as relaxing enzyme,untwisting enzyme or swivelase, catalyses the ATP-independent breakage of single- [...] | DNA ligase (NAD+); DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double- stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA. | 0.584 |
| azo0952 | napG | azo0952 | azo3941 | Conserved hypothetical protein, 38% identity (50% similarity) to TrEMBL;Q7WXG4 Signal Peptide Present.TMH not Present. Has PF04471:Restriction endonuclease;(IPR007560:Mrr_cat):Prokaryotic family found in type II restriction enzymes containing the hallmark (D/E)-(D/E)XK active site. Presence of catalytic residues implicates this region in the enzymatic cleavage of DNA. PF01396:Topoisomerase DNA binding C4 zinc finger;(IPR000380 DNA_tpisomrase):Prokaryotic topoisomerase I, otherwise known as relaxing enzyme,untwisting enzyme or swivelase, catalyses the ATP-independent breakage of single- [...] | Probable ferredoxin-type protein napG. Homology to napG of E. coli of 57% (sprot|NAPG_ECOLI). Involved in electron transfer in a wide variety of metabolic reactions. InterPro: MauM/NapG family ferredoxin-type protein (IPR004494); 7 Fe ferredoxin (IPR000813); 4Fe-4S ferredoxin; iron-sulfur binding domain (IPR001450) Pfam: 4Fe-4S binding domain Tigrfam: mauM_napG: MauM/NapG family ferredoxin-type protein no signal peptide no TMHs; High confidence in function and specificity. | 0.900 |
| azo0952 | padC | azo0952 | azo1947 | Conserved hypothetical protein, 38% identity (50% similarity) to TrEMBL;Q7WXG4 Signal Peptide Present.TMH not Present. Has PF04471:Restriction endonuclease;(IPR007560:Mrr_cat):Prokaryotic family found in type II restriction enzymes containing the hallmark (D/E)-(D/E)XK active site. Presence of catalytic residues implicates this region in the enzymatic cleavage of DNA. PF01396:Topoisomerase DNA binding C4 zinc finger;(IPR000380 DNA_tpisomrase):Prokaryotic topoisomerase I, otherwise known as relaxing enzyme,untwisting enzyme or swivelase, catalyses the ATP-independent breakage of single- [...] | Conserved hypothetical phenylacetyl-CoA:acceptor oxidoreductase. Homology to padC of A. evansiin of 61% (trembl|Q8L3B5). Probably involved in the transfer of electrons from the quinone pool to the type-c cytochromes (By similarity). Pfam: 4Fe-4S binding domain. Tigrfam: napF: ferredoxin-type protein NapF. no signal peptide. no TMHs; Family membership. | 0.890 |
| azo0952 | polA | azo0952 | azo3600 | Conserved hypothetical protein, 38% identity (50% similarity) to TrEMBL;Q7WXG4 Signal Peptide Present.TMH not Present. Has PF04471:Restriction endonuclease;(IPR007560:Mrr_cat):Prokaryotic family found in type II restriction enzymes containing the hallmark (D/E)-(D/E)XK active site. Presence of catalytic residues implicates this region in the enzymatic cleavage of DNA. PF01396:Topoisomerase DNA binding C4 zinc finger;(IPR000380 DNA_tpisomrase):Prokaryotic topoisomerase I, otherwise known as relaxing enzyme,untwisting enzyme or swivelase, catalyses the ATP-independent breakage of single- [...] | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.642 |
| azo0952 | ssb | azo0952 | azo3385 | Conserved hypothetical protein, 38% identity (50% similarity) to TrEMBL;Q7WXG4 Signal Peptide Present.TMH not Present. Has PF04471:Restriction endonuclease;(IPR007560:Mrr_cat):Prokaryotic family found in type II restriction enzymes containing the hallmark (D/E)-(D/E)XK active site. Presence of catalytic residues implicates this region in the enzymatic cleavage of DNA. PF01396:Topoisomerase DNA binding C4 zinc finger;(IPR000380 DNA_tpisomrase):Prokaryotic topoisomerase I, otherwise known as relaxing enzyme,untwisting enzyme or swivelase, catalyses the ATP-independent breakage of single- [...] | Single-strand DNA-binding protein; Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism. | 0.696 |
| azo1252 | azo0952 | azo1252 | azo0952 | Conserved hypothetical membrane protein. Homology to XCC3430 of Xanthomonas campestris of 38% (trembl:Q8P5B1). Has PF04892, VanZ like family;IPR006976; This family contains several examples of the VanZ protein,but also contains examples of phosphotransbutyrylases. VanZ confers low-level resistance to the glycopeptide antibiotic teicoplanin (Te). Analysis of cytoplasmic peptidoglycan precursors, accumulated in the presence of ramoplanin, showed that VanZ-mediated Te resistance does not involve incorporation of a substituent of D-alanine into the peptidoglycan precursors. no signal pepti [...] | Conserved hypothetical protein, 38% identity (50% similarity) to TrEMBL;Q7WXG4 Signal Peptide Present.TMH not Present. Has PF04471:Restriction endonuclease;(IPR007560:Mrr_cat):Prokaryotic family found in type II restriction enzymes containing the hallmark (D/E)-(D/E)XK active site. Presence of catalytic residues implicates this region in the enzymatic cleavage of DNA. PF01396:Topoisomerase DNA binding C4 zinc finger;(IPR000380 DNA_tpisomrase):Prokaryotic topoisomerase I, otherwise known as relaxing enzyme,untwisting enzyme or swivelase, catalyses the ATP-independent breakage of single- [...] | 0.584 |
| azo2931 | azo0952 | azo2931 | azo0952 | Conserved hypothetical protein. Homology to gsu0911 of G. sulfurreducens of 38% (tremblnew|AAR34238). Pfam: 4Fe-4S binding domain. no signal peptide. no TMHs. | Conserved hypothetical protein, 38% identity (50% similarity) to TrEMBL;Q7WXG4 Signal Peptide Present.TMH not Present. Has PF04471:Restriction endonuclease;(IPR007560:Mrr_cat):Prokaryotic family found in type II restriction enzymes containing the hallmark (D/E)-(D/E)XK active site. Presence of catalytic residues implicates this region in the enzymatic cleavage of DNA. PF01396:Topoisomerase DNA binding C4 zinc finger;(IPR000380 DNA_tpisomrase):Prokaryotic topoisomerase I, otherwise known as relaxing enzyme,untwisting enzyme or swivelase, catalyses the ATP-independent breakage of single- [...] | 0.890 |
| azo2931 | padC | azo2931 | azo1947 | Conserved hypothetical protein. Homology to gsu0911 of G. sulfurreducens of 38% (tremblnew|AAR34238). Pfam: 4Fe-4S binding domain. no signal peptide. no TMHs. | Conserved hypothetical phenylacetyl-CoA:acceptor oxidoreductase. Homology to padC of A. evansiin of 61% (trembl|Q8L3B5). Probably involved in the transfer of electrons from the quinone pool to the type-c cytochromes (By similarity). Pfam: 4Fe-4S binding domain. Tigrfam: napF: ferredoxin-type protein NapF. no signal peptide. no TMHs; Family membership. | 0.765 |
| fdhB | azo0952 | azo3481 | azo0952 | Probable formate dehydrogenase iron-sulfur subunit. Homology to fdhB of W. succinogenes of 63% (SWISSPROT:FDHB_WOLSU) THIS CHAIN IS AN ELECTRON TRANSFER UNIT CONTAINING 18 CYSTEINE RESIDUES 16 OF WHICH OCCUR IN THREE CLUSTERS. InterPro: 4Fe-4S ferredoxin iron-sulfur binding domain (IPR001450); 7Fe ferredoxin (IPR000813); 3Fe-4S ferredoxin (IPR001080) Pfam: 4Fe-4S binding domain no signal peptide no TMHs; High confidence in function and specificity. | Conserved hypothetical protein, 38% identity (50% similarity) to TrEMBL;Q7WXG4 Signal Peptide Present.TMH not Present. Has PF04471:Restriction endonuclease;(IPR007560:Mrr_cat):Prokaryotic family found in type II restriction enzymes containing the hallmark (D/E)-(D/E)XK active site. Presence of catalytic residues implicates this region in the enzymatic cleavage of DNA. PF01396:Topoisomerase DNA binding C4 zinc finger;(IPR000380 DNA_tpisomrase):Prokaryotic topoisomerase I, otherwise known as relaxing enzyme,untwisting enzyme or swivelase, catalyses the ATP-independent breakage of single- [...] | 0.890 |
| fldA | azo0952 | azo2544 | azo0952 | Hypothetical protein FldA, 78% identity (86% similarity) to TrEMBL;Q6N0R5,Q8PF30(47% identity). 45% identity to ybhH of SwissProt;P75762(E.coli) Has PF04303,Protein of unknown function (DUF453);IPR007400; FldA (Q9L3A0) is thought to be involved in the degradation of the polyaromatic hydrocarbon fluorene by Sphingomonas sp. LB126. Has PF01678, Diaminopimelate epimerase;IPR001653 DAP_epimerase: Diaminopimelate epimerase contains two domains of the same alpha/beta fold, both contained in this family.Diaminopimelate epimerase (EC:5.1.1.7) catalyzes the isomeriazation of L,L- to D,L-meso-di [...] | Conserved hypothetical protein, 38% identity (50% similarity) to TrEMBL;Q7WXG4 Signal Peptide Present.TMH not Present. Has PF04471:Restriction endonuclease;(IPR007560:Mrr_cat):Prokaryotic family found in type II restriction enzymes containing the hallmark (D/E)-(D/E)XK active site. Presence of catalytic residues implicates this region in the enzymatic cleavage of DNA. PF01396:Topoisomerase DNA binding C4 zinc finger;(IPR000380 DNA_tpisomrase):Prokaryotic topoisomerase I, otherwise known as relaxing enzyme,untwisting enzyme or swivelase, catalyses the ATP-independent breakage of single- [...] | 0.789 |
| leuS | azo0952 | azo3215 | azo0952 | Leucine--tRNA ligase; Unnamed protein product; Region start changed from 3544790 to 3544922 (-132 bases); Belongs to the class-I aminoacyl-tRNA synthetase family. | Conserved hypothetical protein, 38% identity (50% similarity) to TrEMBL;Q7WXG4 Signal Peptide Present.TMH not Present. Has PF04471:Restriction endonuclease;(IPR007560:Mrr_cat):Prokaryotic family found in type II restriction enzymes containing the hallmark (D/E)-(D/E)XK active site. Presence of catalytic residues implicates this region in the enzymatic cleavage of DNA. PF01396:Topoisomerase DNA binding C4 zinc finger;(IPR000380 DNA_tpisomrase):Prokaryotic topoisomerase I, otherwise known as relaxing enzyme,untwisting enzyme or swivelase, catalyses the ATP-independent breakage of single- [...] | 0.733 |
| leuS | ligA | azo3215 | azo2001 | Leucine--tRNA ligase; Unnamed protein product; Region start changed from 3544790 to 3544922 (-132 bases); Belongs to the class-I aminoacyl-tRNA synthetase family. | DNA ligase (NAD+); DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double- stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA. | 0.921 |
| leuS | polA | azo3215 | azo3600 | Leucine--tRNA ligase; Unnamed protein product; Region start changed from 3544790 to 3544922 (-132 bases); Belongs to the class-I aminoacyl-tRNA synthetase family. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.680 |
| ligA | azo0952 | azo2001 | azo0952 | DNA ligase (NAD+); DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double- stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA. | Conserved hypothetical protein, 38% identity (50% similarity) to TrEMBL;Q7WXG4 Signal Peptide Present.TMH not Present. Has PF04471:Restriction endonuclease;(IPR007560:Mrr_cat):Prokaryotic family found in type II restriction enzymes containing the hallmark (D/E)-(D/E)XK active site. Presence of catalytic residues implicates this region in the enzymatic cleavage of DNA. PF01396:Topoisomerase DNA binding C4 zinc finger;(IPR000380 DNA_tpisomrase):Prokaryotic topoisomerase I, otherwise known as relaxing enzyme,untwisting enzyme or swivelase, catalyses the ATP-independent breakage of single- [...] | 0.584 |
| ligA | leuS | azo2001 | azo3215 | DNA ligase (NAD+); DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double- stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA. | Leucine--tRNA ligase; Unnamed protein product; Region start changed from 3544790 to 3544922 (-132 bases); Belongs to the class-I aminoacyl-tRNA synthetase family. | 0.921 |