STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
gufAPutative GufA protein. 31% Zn_transpt_Zip.InterPro: ZIP Zinc transporter Pfam: PF02535; Zip; 1. TMHelix: 9. Signal peptide present; Specificity unclear. (302 aa)    
Predicted Functional Partners:
azo1466
Putative superoxide dismutase; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family.
  
  
 0.655
cfa1
Probable cyclopropane-fatty-acyl-phospholipid synthase. Homology to cfa of E. coli of 54% (Sprot:CFA_ECOLI) TRANSFERS A METHYLENE GROUP FROM S-ADENOSYL-L-METHIONINE TO THE CIS DOUBLE BOND OF AN UNSATURATED FATTY ACID CHAIN RESULTING IN THE REPLACEMENT OF THE DOUBLE BOND WITH A METHYLENE BRIDGE. Pfam: Cyclopropane-fatty-acyl-phosphotlipid no signal peptide no TMHs; High confidence in function and specificity.
       0.541
zitB
Zinc transporter zitB (formaly ybgR).Involved in zinc efflux across the cytoplasmic membrane thus reducing zinc accumulation in the cytoplasm and rendering bacteria more resistant to zinc. It may contribute to zinc homeostasis at low concentrations of zinc (By similarity).The E.coli zitB gene encodes a Zn(II) transporter belonging to the cation diffusion facilitator family; High confidence in function and specificity.
   
 0.460
czcD2
Putative cobalt-zinc-cadmium resistance protein; CzcD: Members of this family are integral membrane proteins that are found to increase tolerance to divalent metal ions such as cadmium, zinc, and cobalt. These proteins are thought to be efflux pumps that remove these ions from cells. 41% Cation_efflux. Pfam:PF01545; Cation_efflux; 1. TMhelix:6; High confidence in function and specificity.
   
 0.449
mauE
Methylamine utilization protein mauE. Homology to mauE of M. extorquens of 37% (sprot|MAUE_METEX) MAY BE SPECIFICALLY INVOLVED IN THE PROCESSING TRANSPORT AND/OR MATURATION OF THE MADH BETA-SUBUNIT. no signal peptide probable 4 TMHs; Family membership.
   
 0.449
ribAB
GTP cyclohydrolase II; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; Belongs to the DHBP synthase family.
      
 0.441
folE
FolE protein; GTP cyclohydrolase I (EC 3.5.4.16) (GTP-CH-I). folE: GTP cyclohydrolase I; High confidence in function and specificity.
    
   0.413
fumC
Fumarate hydratase; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
  
    0.411
isiB
Probable flavodoxin; Low-potential electron donor to a number of redox enzymes. Belongs to the flavodoxin family.
  
    0.406
Your Current Organism:
Azoarcus sp. BH72
NCBI taxonomy Id: 62928
Other names: A. sp. BH72
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