| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| dadA1 | gcvP | azo0967 | azo1285 | Probable D-amino acid dehydrogenase small subunit; The L-alanine catabolic pathway proceeds in two steps: racemization of the L-isomer to D-alanine by alanine racemase and oxidative deamination of D-alanine to pyruvate and ammonia by D- amino acid dehydrogenase. Similar to trembl|Q7NRT8 (52%) and to sprot|DADA_ECOLI (40%). Pfam (PF01266): D-amino acid oxidase; Specificity unclear. | Glycine cleavage system P-protein; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. | 0.792 |
| dadA1 | gcvT | azo0967 | azo1287 | Probable D-amino acid dehydrogenase small subunit; The L-alanine catabolic pathway proceeds in two steps: racemization of the L-isomer to D-alanine by alanine racemase and oxidative deamination of D-alanine to pyruvate and ammonia by D- amino acid dehydrogenase. Similar to trembl|Q7NRT8 (52%) and to sprot|DADA_ECOLI (40%). Pfam (PF01266): D-amino acid oxidase; Specificity unclear. | Glycine cleavage T proteins are part of the glycine cleavage multienzyme complex (GCV) found in bacteria and the mitochondria of eukaryotes. The T-protein is an aminomethyl transferase that catalyses the following reaction: (6S)-tetrahydrofolate + S-aminomethyldihydrolipoylprotein = (6R)-5,10-methylenetetrahydrofolate + NH3 + dihydrolipoylprotein Similar to sprot|GCST_NITEU (60%). Pfam: Glycine cleavage T-protein (aminomethyltransferase) TIGRfam (TIGR00528): Glycine cleavage T-protein (aminomethyl transferase); High confidence in function and specificity. | 0.728 |
| dadA1 | gltB | azo0967 | azo3642 | Probable D-amino acid dehydrogenase small subunit; The L-alanine catabolic pathway proceeds in two steps: racemization of the L-isomer to D-alanine by alanine racemase and oxidative deamination of D-alanine to pyruvate and ammonia by D- amino acid dehydrogenase. Similar to trembl|Q7NRT8 (52%) and to sprot|DADA_ECOLI (40%). Pfam (PF01266): D-amino acid oxidase; Specificity unclear. | Ferredoxin-dependent glutamate synthase,; Specificity unclear. | 0.879 |
| dadA1 | hisC2 | azo0967 | azo3348 | Probable D-amino acid dehydrogenase small subunit; The L-alanine catabolic pathway proceeds in two steps: racemization of the L-isomer to D-alanine by alanine racemase and oxidative deamination of D-alanine to pyruvate and ammonia by D- amino acid dehydrogenase. Similar to trembl|Q7NRT8 (52%) and to sprot|DADA_ECOLI (40%). Pfam (PF01266): D-amino acid oxidase; Specificity unclear. | Histidinol-phosphate aminotransferase, hisC. Similar to sprot|HIS8_PSESM (64%). Aminotransferases share certain mechanistic features with other pyridoxal-phosphate dependent enzymes, such as the covalent binding of the pyridoxal-phosphate group to a lysine residue. On the basis of sequence similarity, these various enzymes can be grouped into class I and class II. InterPro (PF00155): Aminotransferase class I and II; High confidence in function and specificity. | 0.747 |
| dadA1 | metH | azo0967 | azo3726 | Probable D-amino acid dehydrogenase small subunit; The L-alanine catabolic pathway proceeds in two steps: racemization of the L-isomer to D-alanine by alanine racemase and oxidative deamination of D-alanine to pyruvate and ammonia by D- amino acid dehydrogenase. Similar to trembl|Q7NRT8 (52%) and to sprot|DADA_ECOLI (40%). Pfam (PF01266): D-amino acid oxidase; Specificity unclear. | Probable methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.618 |
| dadA1 | ooxA | azo0967 | azo0210 | Probable D-amino acid dehydrogenase small subunit; The L-alanine catabolic pathway proceeds in two steps: racemization of the L-isomer to D-alanine by alanine racemase and oxidative deamination of D-alanine to pyruvate and ammonia by D- amino acid dehydrogenase. Similar to trembl|Q7NRT8 (52%) and to sprot|DADA_ECOLI (40%). Pfam (PF01266): D-amino acid oxidase; Specificity unclear. | Putative opine oxidase subunit A. Homology to ooxA of A. tumefaciens of 37% (sprot|OOXA_AGRT4). OXIDATIVE CLEAVAGE OF OCTOPINE INTO L-ARGININE AND PYRUVATE (BY SIMILARITY). InterPro: FAD-dependent pyridine nucleotide-disulphide oxidoreductase (IPR001327), NAD-bining site (IPR000205) Pfam: Pyridine nucleotide-disulphide oxidoreductase no signal peptide no TMHs; Family membership. | 0.806 |
| dadA1 | soxF | azo0967 | azo1141 | Probable D-amino acid dehydrogenase small subunit; The L-alanine catabolic pathway proceeds in two steps: racemization of the L-isomer to D-alanine by alanine racemase and oxidative deamination of D-alanine to pyruvate and ammonia by D- amino acid dehydrogenase. Similar to trembl|Q7NRT8 (52%) and to sprot|DADA_ECOLI (40%). Pfam (PF01266): D-amino acid oxidase; Specificity unclear. | Probable sulfide dehydrogenase, falvoprotein subunit (Flavocytochrome C flavoprotein subunit). Homology to fccB of C. vinosum of 40% (sprot|DHSU_CHRVI). Pfam: Pyridine nucleotide-disulphide oxidoreductase signal peptide no TMHs; Family membership. | 0.787 |
| dadA1 | thiG | azo0967 | azo3969 | Probable D-amino acid dehydrogenase small subunit; The L-alanine catabolic pathway proceeds in two steps: racemization of the L-isomer to D-alanine by alanine racemase and oxidative deamination of D-alanine to pyruvate and ammonia by D- amino acid dehydrogenase. Similar to trembl|Q7NRT8 (52%) and to sprot|DADA_ECOLI (40%). Pfam (PF01266): D-amino acid oxidase; Specificity unclear. | Thiamine biosynthesis protein; Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S. | 0.627 |
| dadA1 | thiS | azo0967 | azo3970 | Probable D-amino acid dehydrogenase small subunit; The L-alanine catabolic pathway proceeds in two steps: racemization of the L-isomer to D-alanine by alanine racemase and oxidative deamination of D-alanine to pyruvate and ammonia by D- amino acid dehydrogenase. Similar to trembl|Q7NRT8 (52%) and to sprot|DADA_ECOLI (40%). Pfam (PF01266): D-amino acid oxidase; Specificity unclear. | Thiamine biosynthesis protein ThiS; Putative sulfur transfer protein involved in thimanin biosynsthesis; High confidence in function and specificity. | 0.594 |
| dadA1 | tyrB | azo0967 | azo1610 | Probable D-amino acid dehydrogenase small subunit; The L-alanine catabolic pathway proceeds in two steps: racemization of the L-isomer to D-alanine by alanine racemase and oxidative deamination of D-alanine to pyruvate and ammonia by D- amino acid dehydrogenase. Similar to trembl|Q7NRT8 (52%) and to sprot|DADA_ECOLI (40%). Pfam (PF01266): D-amino acid oxidase; Specificity unclear. | Probable aromatic-amino-acid aminotransferase. Homology to tyrB of E. coli of 52% (sprot|TYRB_ECO). Is involved in biosynthesis of phe, tyr, asp and leu. Catalyse the reactiion: an aromatic amino acid + 2-oxoglutarate = an aromatic oxo acid + l-glutamate. Pfam: Aminotransferase class I and II no signal peptide no TMHs; High confidence in function and specificity. | 0.749 |
| gcvP | dadA1 | azo1285 | azo0967 | Glycine cleavage system P-protein; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. | Probable D-amino acid dehydrogenase small subunit; The L-alanine catabolic pathway proceeds in two steps: racemization of the L-isomer to D-alanine by alanine racemase and oxidative deamination of D-alanine to pyruvate and ammonia by D- amino acid dehydrogenase. Similar to trembl|Q7NRT8 (52%) and to sprot|DADA_ECOLI (40%). Pfam (PF01266): D-amino acid oxidase; Specificity unclear. | 0.792 |
| gcvP | gcvT | azo1285 | azo1287 | Glycine cleavage system P-protein; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. | Glycine cleavage T proteins are part of the glycine cleavage multienzyme complex (GCV) found in bacteria and the mitochondria of eukaryotes. The T-protein is an aminomethyl transferase that catalyses the following reaction: (6S)-tetrahydrofolate + S-aminomethyldihydrolipoylprotein = (6R)-5,10-methylenetetrahydrofolate + NH3 + dihydrolipoylprotein Similar to sprot|GCST_NITEU (60%). Pfam: Glycine cleavage T-protein (aminomethyltransferase) TIGRfam (TIGR00528): Glycine cleavage T-protein (aminomethyl transferase); High confidence in function and specificity. | 0.999 |
| gcvP | gltB | azo1285 | azo3642 | Glycine cleavage system P-protein; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. | Ferredoxin-dependent glutamate synthase,; Specificity unclear. | 0.951 |
| gcvP | metH | azo1285 | azo3726 | Glycine cleavage system P-protein; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. | Probable methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.952 |
| gcvP | ooxA | azo1285 | azo0210 | Glycine cleavage system P-protein; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. | Putative opine oxidase subunit A. Homology to ooxA of A. tumefaciens of 37% (sprot|OOXA_AGRT4). OXIDATIVE CLEAVAGE OF OCTOPINE INTO L-ARGININE AND PYRUVATE (BY SIMILARITY). InterPro: FAD-dependent pyridine nucleotide-disulphide oxidoreductase (IPR001327), NAD-bining site (IPR000205) Pfam: Pyridine nucleotide-disulphide oxidoreductase no signal peptide no TMHs; Family membership. | 0.836 |
| gcvP | soxF | azo1285 | azo1141 | Glycine cleavage system P-protein; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. | Probable sulfide dehydrogenase, falvoprotein subunit (Flavocytochrome C flavoprotein subunit). Homology to fccB of C. vinosum of 40% (sprot|DHSU_CHRVI). Pfam: Pyridine nucleotide-disulphide oxidoreductase signal peptide no TMHs; Family membership. | 0.836 |
| gcvT | dadA1 | azo1287 | azo0967 | Glycine cleavage T proteins are part of the glycine cleavage multienzyme complex (GCV) found in bacteria and the mitochondria of eukaryotes. The T-protein is an aminomethyl transferase that catalyses the following reaction: (6S)-tetrahydrofolate + S-aminomethyldihydrolipoylprotein = (6R)-5,10-methylenetetrahydrofolate + NH3 + dihydrolipoylprotein Similar to sprot|GCST_NITEU (60%). Pfam: Glycine cleavage T-protein (aminomethyltransferase) TIGRfam (TIGR00528): Glycine cleavage T-protein (aminomethyl transferase); High confidence in function and specificity. | Probable D-amino acid dehydrogenase small subunit; The L-alanine catabolic pathway proceeds in two steps: racemization of the L-isomer to D-alanine by alanine racemase and oxidative deamination of D-alanine to pyruvate and ammonia by D- amino acid dehydrogenase. Similar to trembl|Q7NRT8 (52%) and to sprot|DADA_ECOLI (40%). Pfam (PF01266): D-amino acid oxidase; Specificity unclear. | 0.728 |
| gcvT | gcvP | azo1287 | azo1285 | Glycine cleavage T proteins are part of the glycine cleavage multienzyme complex (GCV) found in bacteria and the mitochondria of eukaryotes. The T-protein is an aminomethyl transferase that catalyses the following reaction: (6S)-tetrahydrofolate + S-aminomethyldihydrolipoylprotein = (6R)-5,10-methylenetetrahydrofolate + NH3 + dihydrolipoylprotein Similar to sprot|GCST_NITEU (60%). Pfam: Glycine cleavage T-protein (aminomethyltransferase) TIGRfam (TIGR00528): Glycine cleavage T-protein (aminomethyl transferase); High confidence in function and specificity. | Glycine cleavage system P-protein; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. | 0.999 |
| gcvT | gltB | azo1287 | azo3642 | Glycine cleavage T proteins are part of the glycine cleavage multienzyme complex (GCV) found in bacteria and the mitochondria of eukaryotes. The T-protein is an aminomethyl transferase that catalyses the following reaction: (6S)-tetrahydrofolate + S-aminomethyldihydrolipoylprotein = (6R)-5,10-methylenetetrahydrofolate + NH3 + dihydrolipoylprotein Similar to sprot|GCST_NITEU (60%). Pfam: Glycine cleavage T-protein (aminomethyltransferase) TIGRfam (TIGR00528): Glycine cleavage T-protein (aminomethyl transferase); High confidence in function and specificity. | Ferredoxin-dependent glutamate synthase,; Specificity unclear. | 0.925 |
| gcvT | metH | azo1287 | azo3726 | Glycine cleavage T proteins are part of the glycine cleavage multienzyme complex (GCV) found in bacteria and the mitochondria of eukaryotes. The T-protein is an aminomethyl transferase that catalyses the following reaction: (6S)-tetrahydrofolate + S-aminomethyldihydrolipoylprotein = (6R)-5,10-methylenetetrahydrofolate + NH3 + dihydrolipoylprotein Similar to sprot|GCST_NITEU (60%). Pfam: Glycine cleavage T-protein (aminomethyltransferase) TIGRfam (TIGR00528): Glycine cleavage T-protein (aminomethyl transferase); High confidence in function and specificity. | Probable methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.944 |
