Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
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experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
azo0972Probable ABC transporter, ATP-binding protein; Thiamine transport ATP-binding protein thiQ. PART OF THE BINDING-PROTEIN-DEPENDENT TRANSPORT SYSTEM TBPA-THIPQ FOR THIAMINE AND TPP. PROBABLY RESPONSIBLE FOR ENERGY COUPLING TO THE TRANSPORT SYSTEM. TREMBL:Q7WH56: 84% identity, 92% similarity Description:putative abc-transporter atp-binding component InterPro: IPR003593; AAA_ATPase. IPR003439; ABC_transporter. Pfam:PF00005; ABC_tran; ProDom PD000006; ABC_transporter; 1. SMART SM00382; AAA recf: DNA replication and repair protein NO transmembrane helices; Function unclear. (264 aa)    
Predicted Functional Partners:
azo0971
Conserved hypothetical ABC transporter, permease protein. PART OF THE BINDING-PROTEIN-DEPENDENT TRANSPORT SYSTEM. PROBABLY RESPONSIBLE FOR THE TRANSLOCATION OF THE SUBSTRATE ACROSS THE MEMBRANE. InterPro: Binding-system dependent bacterial transporters (araH livH/limM families) (IPR001851) Pfam: Branched-chain amino acid transport system/permease component no signal peptide 8 TMHs 2A78: Carboxylate/Amino Acid/Amine Tran; Specificity unclear.
 
    0.985
azo0970
Conserved hypothetical secreted protein. Homology to bb3356 of B. bronchiseptica of 83% (trembl|Q7WH54). Pfam: DUF534 This is a family of putative secreted proteins of unknown function. signal peptide no TMHs; Conserved hypothetical protein.
 
    0.922
azo2902
Probable integral membrane protein; TREMBL:Q8XWQ6: 39% identity, 56% similarity Hypothetical protein HI1703. InterPro: IPR005495; YjgP_YjgQ. Pfam: PF03739;Pfam :DUF214:Predicted permease Members of this family are predicted integral membrane proteins of unknown function. They are about 350 amino acids long, contain about 6 transmembrane regions and may be permeases, although there is no verification of this. subcellular location:integral membrane protein (potential). similarity:strong, to h.influenzae hi1703 2a69: Auxin Efflux Carrier TMHMM predicted 6 transmembrane helices; Conserved [...]
     
  0.751
azo2903
Conserved hypothetical membrane protein. TREMBL:Q8XWQ7: 40% identity; 55% similarity: probable integral membrane protein InterPro:IPR005495; YjgP_YjgQ. Pfam:PF03739; YjgP_YjgQ :UbiA : UbiA prenyltransferase family Pfam:DUF112:Integral membrane protein DUF112 Signal peptide present (Signal P predicted). Transmembrane helices: 5 (TMHMM predicted); Conserved hypothetical protein.
     
  0.751
yhbG
Probable ABC transporter ATP-binding protein HI1148. ATP-binding cassette (ABC) transporters are multidomain membrane proteins, responsible for the controlled efflux and influx of substances (allocrites) across cellular membranes. TREMBL:Q7NST9: 64% identity,75% similarity InterPro: IPR003593; AAA_ATPase. IPR003439; ABC_transporter. IPR000767; Disease_resist. IPR003016; Lipoyl_BS. Pfam PF00005; ABC_tran; 1 mobB: molybdopterin-guanine dinucleoti TMH's present 0; High confidence in function and specificity.
     
  0.715
azo0807
Conserved hypothetical membrane protein Similar to TREMBL:Q7P0W7 (65% identity); TREMBL:Q82SF6 (65% identity); TREMBL:Q7VSZ9 (57% identity). InterPro (IPR003453): Domain of unknown function DUF140. Pfam (PF02405): Domain of unknown function DUF140. TIGRFAM (TIGR00056): Conserved hypothetical protein. TMHMM reporting five transmembrane helices.
     
  0.635
azo1274
Putative ABC transporter permease protein; TREMBL:Q88RI7 (56% identity); TREMBL:Q8PGP6 (42% identity). Pfam (PF02405): Domain of unknown function DUF140. TIGRFAM (TIGR00056): Conserved hypothetical protein. TMHMM reporting six transmembrane helices; Specificity unclear.
     
  0.635
azo1691
Conserved hypothetical membrane protein. Similar to TREMBL:Q8Y2M2 (43% identity). InterPro (IPR003453): Domain of unknown function DUF140. Pfam (PF02405): Domain of unknown function DUF140. TIGRFAM (TIGR00056): Conserved hypothetical protein. TMHMM reporting five transmembrane helices.
     
  0.635
glnM
Putative glutamine transport permease protein. Homology to glnM of B. subtilis of 30% (TREMBL:O34671) Probably part of the binding-protein-dependent transport system of amino acids. Probably responsible for the translocation of the substrate across the membrane InterPro: Binding-protein-dependent transport systems inner membrane component (IPR000515) Pfam: Binding-protein-dependent transport systems inner membrane component no signal peptide probable 5 TMHs; Family membership.
     
  0.600
glnP
Glutamate/aspartate transport system permease protein gltJ. Homology to glnP of B. subtilis of 23% (CAA93320). PART OF THE BINDING-PROTEIN-DEPENDENT TRANSPORT SYSTEM FOR AMINO ACID; PROBABLY RESPONSIBLE FOR THE TRANSLOCATION OF THE SUBSTRATE ACROSS THE MEMBRANE. InterPro: Binding-protein-dependent transport systems inner membrane component (IPR000515) Pfam: Binding-protein-dependent transport systems inner membrane component HTH-motif probable 4 TMHs no signal peptide; Family membership.
     
  0.600
Your Current Organism:
Azoarcus sp. BH72
NCBI taxonomy Id: 62928
Other names: A. sp. BH72
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