Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
glcCGlc operon transcriptional activator,; High confidence in function and specificity. (239 aa)    
Predicted Functional Partners:
frlR
Putative GntR-family transcriptional regulator,; Family membership.
  
  
 0.605
allR
Probable negative regulator of allantoin and glyoxylate utilization operons,; High confidence in function and specificity.
 
  
 0.581
ligI
Probable 2-pyrone-4,6-dicarboxylate hydrolase. Homology to ligI of S. paucimobilis of 55% (tremble:O87170) Pfam: Amidohydrolase no signal peptide no TMHs; High confidence in function and specificity.
      0.568
glcD1
Probable glycolate oxidase subunit glcD. Homology to glcD of E. coli of 64% (sprot|GLCD_ECOLI) InterPro: FAD linked oxidase C-terminal (IPR004113); FAD linked oxidase N-terminal (IPR006093) Pfam: FAD binding domain; FAD linked oxidase, C-terminal domain Tigrfam: glcD: glycolate oxidase subunit GlcD no signal peptide no TMHs; High confidence in function and specificity.
     
 0.540
hemY
HemY protein. involved in a late step of protoheme ix synthesis; High confidence in function and specificity.
       0.471
hemX
Putative uroporphyrin-III C-methyltransferase. catalytic activity: 2 s-adenosyl-l-methionine + uroporphyrin iii = 2 s-adenosyl-l-homocysteine + sirohydrochlorin. pathway: siroheme and cobalamin biosynthesis; Specificity unclear.
       0.457
hemD
HemD protein; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III.
       0.451
bphS
GntR family transcriptional regulator,; High confidence in function and specificity.
  
  
 0.446
hemC
Hydroxymethylbilane synthase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family.
       0.431
Your Current Organism:
Azoarcus sp. BH72
NCBI taxonomy Id: 62928
Other names: A. sp. BH72
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