STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
glcD1Probable glycolate oxidase subunit glcD. Homology to glcD of E. coli of 64% (sprot|GLCD_ECOLI) InterPro: FAD linked oxidase C-terminal (IPR004113); FAD linked oxidase N-terminal (IPR006093) Pfam: FAD binding domain; FAD linked oxidase, C-terminal domain Tigrfam: glcD: glycolate oxidase subunit GlcD no signal peptide no TMHs; High confidence in function and specificity. (499 aa)    
Predicted Functional Partners:
glcE
Probable glycolate oxidase subunit GlcE. Homology to glcE of E. coli of 47% (sprot|GLCE_ECOLI) InterPro: FAD linked oxidase N-terminal (IPR006093) Pfam: FAD binding domain Tigrfam: glcD: glycolate oxidase subunit GlcD no singla peptide no TMHs; High confidence in function and specificity.
 
 0.995
glcF
Probable glycolate oxidase iron-sulfur subunit. Homology to glcF of E. coli of 56% (sprot|GLCF_ECOLI) Pfam: Domain of unknown function (DUF224) (192-256 aa; 329-391 aa) no signal peptide no TMHs; High confidence in function and specificity.
 
 
 0.992
azo0638
Conserved hypothtecial protein. Homology to Avin02002811 of Azotobacter vinelandii of 50% (gi|23103464|ref|ZP_00089946.1|(NBCI ENTREZ)). InterPro: Domain of unknown function DUF224 (IPR004017). no signal peptide. no TMHs.
 
 0.941
azo0062
Conserved hypothetical protein. Homology to MCA0287 of Methylococcus capsulatus of 48% (trembl:Q60C24). no domains predicted. no signal peptide. no TMHs.
 
 0.939
azo1615
TREMBL:Q7VSFO: Probable hydrolase, 55% identity,63% similarity Phosphoglycolate phosphatase (PGP). InterPro:PR006402; HAD-SF-IA-v3. IPR006439; HAD_SF_A_v1. IPR005834; Hydrolase. Pfam:PF00702; Hydrolase; Haloacid dehaloginase like hydrolase TIGRFAMs:TIGR01549; HAD-SF-IA-v1; TIGR01509; HAD-SF-IA-v3; serB: phosphoserine phosphatase SerB hstdl_phs_rel: histidinol phosphatase-; Function unclear.
    
 0.930
cbbZ
Probable phosphoglycolate phosphatase; Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress. Belongs to the HAD-like hydrolase superfamily. CbbY/CbbZ/Gph/YieH family.
    
 0.930
hoxF
Probable hydrogen dehydrogenase, alpha subunit. Homology to hoxF of A. eutrophus of 41% (sprot|HOXF_ALCEU). SUBUNITS ALPHA AND GAMMA OF HOXS CONSTITUTE AN NADH-OXIDOREDUCTASE. InterPro: Respiratory-chain NADH dehydrogenase 51 Kd subunit (IPR001949); Respiratory-chain NADH dehydrogenase 24 Kd subunit (IPR002023) Pfam: Respiratory-chain NADH dehydrogenase 24 Kd subunit; Respiratory-chain NADH dehydrogenase 51 Kd subunit no signal peptide no TMHs; High confidence in function and specificity.
   
   0.757
fdh1B
Probable formate dehydrogenase (NADP+), beta subunit Homology to fdh1B of M. extorpuens of 55% (trembl|Q8KTI8) Pfam: Respiratory-chain NADH dehydrogenase 24 kD subunit; Respiratory-chain NADH dehydrogenase 51 kD subunit. no signal peptide no TMHs; High confidence in function and specificity.
   
   0.757
gltB
Ferredoxin-dependent glutamate synthase,; Specificity unclear.
    
 0.739
maeB1
Probable malate dehydrogenase (oxaloacetate-decarboxylating) (NADP+) (EC 1.1.1.40) (NADP-ME). Homology to dme of S. meliloti of 60% (sprot|MAO1_RHIME). Required for symbiotic nitrogen fixation. Plays a key role in the conversion of malate to acetyl-CoA for efficient tricarboxylic acid cycle function in nitrogen-fixating bacteria. Tigrfam: pta: phosphotransacetylase Pfam: Malic enzyme; Phosphate acetyl/butaryltransferase no signal peptide no TMHs; High confidence in function and specificity.
  
 
 0.719
Your Current Organism:
Azoarcus sp. BH72
NCBI taxonomy Id: 62928
Other names: A. sp. BH72
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