STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
rlmMConserved hypothetical protein; Catalyzes the 2'-O-methylation at nucleotide C2498 in 23S rRNA; Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily. (364 aa)    
Predicted Functional Partners:
tas
Probable oxidoreductase Tas. Homology to tas of E. coli of 51% (sprot|TAS_ECOLI). InterPro: Aldo/keto reductase family (IPR001395) Pfam: Aldo/keto reductase family no signal peptide no TMHs; Function unclear.
       0.545
azo0190
Conserved hypothetical protein. Homology to an orf of R. oxalatica of 31% (trembl|Q84ES1). Pfam: 37-kD nucleoid-associaed bacterial protein The Escherichia coli nucleoid contains DNA in a condensed but functional form. Analysis of proteins released from isolated spermidine nucleoids after treatment with DNase I reveals significant amounts of two proteins not previously detected in wild-type Escherichia coli. Partial amino-terminal sequencing has identified them as the products of rdgC and yejK. no signal peptide no TMHs.
  
    0.537
yfcK
D-amino-acid oxidase; Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34; In the N-terminal section; belongs to the methyltransferase superfamily. tRNA (mnm(5)s(2)U34)-methyltransferase family.
  
   
 0.469
rhlE2
Putative ATP-dependent RNA helicase rhlE; Family membership; Belongs to the DEAD box helicase family.
       0.446
azo3521
Conserved hypothetical peptidase. Homology to ebA3686 of Azoarcus sp. EbN1 of 45% (gnl|keqq|eba:ebA3686(KEGG)). Pfam: Peptidase family M48. signal peptide. 1 TMHs; Conserved hypothetical protein.
  
     0.423
azo1496
Conserved Hypothetical protein Signal Peptide present. Has Prosite PS00380; RHODANESE_1; Rhodanese (thiosulfate sulfurtransferase) (EC 2.8.1.1)is an enzyme which catalyzes the transfer of the sulfane atom of thiosulfate to cyanide, to form sulfite and thiocyanate. In vertebrates, rhodanese is a mitochondrial enzyme of about 300 amino-acid residues involved in forming iron-sulfur complexes and cyanide detoxification. A cysteine residue takes part in the catalytic mechanism.
  
     0.403
gch
Probable GTP cyclohydrolase I; Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1).
 
    0.402
Your Current Organism:
Azoarcus sp. BH72
NCBI taxonomy Id: 62928
Other names: A. sp. BH72
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