Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ugpBGlycerol-3-phosphate-binding periplasmic protein precursor. SN-glycerol-3-phosphate and glycerophosphoryl diester-binding protein interacts with the binding protein-dependent transport system ugpACE. 30% SBP_bac_1.IPR006061; SBP_dom1. Pfam:PF01547; SBP_bac_1; 1. Signal peptide:present; High confidence in function and specificity. (432 aa)    
Predicted Functional Partners:
ugpQ
Probable glycerophosphodiester phosphodiesterase. Homology to ugpQ of E. coli of 45% (sprot|UGPQ_ECOLI). GLYCEROPHOSPHORYL DIESTER PHOSPHODIESTERASE HYDROLYZES DEACYLATED PHOSPHOLIPIDS TO G3P AND THE CORRESPONDING ALCOHOLS. Pfam: Glycerophosporyl diester phosphodiesterase no signal peptide; High confidence in function and specificity.
 
  
 0.904
azo2910
ATP-binding cassette (ABC) transporters form a large family of proteins responsible for translocation of a variety of compounds across biological membranes. They are composed of two transmembrane domains responsible for binding and transport and two nucleotide-binding domains responsible for coupling the energy of ATP hydrolysis to conformational changes in the TMDs, TREMBL:Q8FZX0 (58% identity); TREMBL:Q8U6Y9 (59% identity). InterPro (IPR003593): AAA ATPase. InterPro (IPR001687): ATP/GTP-binding site motif A (P-loop). InterPro (IPR003439): ABC transporter. Pfam (PF00005): ABC transpor [...]
     
 0.861
dppA
Part of the ABC transporter complex dppABCD involved in dipeptide import. Similar to the dipeptide periplasmic-binding protein dppA in E.coli. DIPEPTIDE-BINDING PROTEIN OF AN OSMOTIC-SHOCKABLE TRANSPORT SYSTEM. DPPA IS ALSO REQUIRED FOR PEPTIDE CHEMOTAXIS. InterPro: Bacterial extracellular solute-binding protein family 5 Signal peptide; Specificity unclear.
  
  
 0.817
azo3061
GGDEF/EAL/PAS/PAC/GAF-domain containing protein.
  
 
 0.817
azo2903
Conserved hypothetical membrane protein. TREMBL:Q8XWQ7: 40% identity; 55% similarity: probable integral membrane protein InterPro:IPR005495; YjgP_YjgQ. Pfam:PF03739; YjgP_YjgQ :UbiA : UbiA prenyltransferase family Pfam:DUF112:Integral membrane protein DUF112 Signal peptide present (Signal P predicted). Transmembrane helices: 5 (TMHMM predicted); Conserved hypothetical protein.
  
  
  0.807
azo1571
Conserved hypothetical protein. Homology to hbpA of N. europaea of 56%. Protein consist of two domains: 1. bacterial extracellular sloute protein with homology to heme-binding protein A which is important for the heme aquisition and 2. a transmembrane helix a the C-terminus (unusual combination). Interpro: Bacterial extracellular solute-binding protein, family 5 (IPR000914) Pfam: Bacterial extracellular solute binding protein Signal peptide one TMH.
  
  
 0.804
dppF
Hypothetical ABC transporter ATP-binding protein yliA. PROBABLY PART OF A BINDING-PROTEIN-DEPENDENT TRANSPORT SYSTEM YLIABCD. PROBABLY RESPONSIBLE FOR ENERGY COUPLING TO THE TRANSPORT SYSTEM. TREMBL:Q82S74: 52% identity, 64% similarity. InterPro: IPR003593; AAA_ATPase. No signal peptide No transmembrane helices. IPR003439; ABC_transporter. IPR010066; Oligo_HPY. Pfam:PF00005; ABC_tran; 2. ProDom: PD000006; ABC_transporter; 1. SMART:SM00382; AAA; 2. TIGRFAMs TIGR01727; oligo_HPY mobB: molybdopterin-guanine dinucleotid; High confidence in function and specificity.
  
  
 0.785
azo0286
Putative ABC transporter permease; Similar to TREMBL:Q7NFQ1 (27% identity); TREMBL:Q97E48 (20% identity); TREMBL:Q8FWI9 (21% identity). TMHMM predicting six transmembrane helices. TC (2.A.6.2): The (Largely Gram-negative Bacterial) Hydrophobe/Amphiphile Efflux-1 (HAE1) Family; Specificity unclear.
     
 0.784
nodJ
ABC transporter permease NodJ; Forms with NodI a membrane transport complex involved in the nodulation process. it probably exports a modified beta-1,4-linked n-acetylglucosamine oligosaccharide. Belongs to the ABC-2 integral membrane protein family, TREMBL:Q7WHD1 (49% identity); SWISSPROT:O52619 (49% identity). InterPro (IPR000412): ABC transporter, family 2. Pfam (PF01061): ABC-2 type transporter. TMHMM reporting six transmembrane helices. TC (3.A.1.102): The Lipooligosaccharide Exporter (LOSE) Family; High confidence in function and specificity.
     
 0.784
azo0813
ABC-2 type transporter permease protein; Similar to TREMBL:Q8XV76 (69% identity); TREMBL:Q7P0X7 (66% identity); TREMBL:Q82SG1 (64% identity). InterPro (IPR000412): ABC transporter, family 2. Pfam (PF01061): ABC-2 type transporter. TMHMM reporting seven transmembrane helices. TC (3.A.1): The ATP-binding Cassette (ABC) Superfamily; Specificity unclear.
     
 0.784
Your Current Organism:
Azoarcus sp. BH72
NCBI taxonomy Id: 62928
Other names: A. sp. BH72
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