STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ugpQProbable glycerophosphodiester phosphodiesterase. Homology to ugpQ of E. coli of 45% (sprot|UGPQ_ECOLI). GLYCEROPHOSPHORYL DIESTER PHOSPHODIESTERASE HYDROLYZES DEACYLATED PHOSPHOLIPIDS TO G3P AND THE CORRESPONDING ALCOHOLS. Pfam: Glycerophosporyl diester phosphodiesterase no signal peptide; High confidence in function and specificity. (249 aa)    
Predicted Functional Partners:
ugpB
Glycerol-3-phosphate-binding periplasmic protein precursor. SN-glycerol-3-phosphate and glycerophosphoryl diester-binding protein interacts with the binding protein-dependent transport system ugpACE. 30% SBP_bac_1.IPR006061; SBP_dom1. Pfam:PF01547; SBP_bac_1; 1. Signal peptide:present; High confidence in function and specificity.
 
  
 0.911
glpA
Putative glycerol-3-phosphate dehydrogenase. Homology to glpA of B. hermsir of 38% (trembl|Q84I21) FAD-dependent glycerol-3-phosphate dehydrogenase catalyzes the conversion of glycerol-3-phosphate into dihydroxyacetone phosphate: sn-glycerol-3-phosphate + acceptor = glycerone phosphate + reduced acceptor. InterPro: D-amino acid oxidase (IPR000927) Pfam: FAD dependent oxidoreductase no signal peptide no TMHs gidA: glucose-inhibited division prot; Family membership.
 
 0.796
glpK
Probable glycerol kinase; Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate; Belongs to the FGGY kinase family.
 
  
 0.773
azo3855
Alkaline phosphatase (EC 3.1.3.1) (ALP)is a zinc and magnesium-containing metalloenzyme which hydrolyzes phosphate esters, optimally at high pH.It is found in nearly all living organisms,with the exception of some plants. 30% Alk_phosphtse.Alkaline phosphatase family Pfam:PF00245; alk_phosphatase; 1. Signal peptide present; High confidence in function and specificity.
  
 
 0.612
azo1011
Conserved hypothetical secreted protein. Homology to Rgel02001790 of Rubrivivax gelatinosus of 45% (gi|47573892|ref|ZP_00243929.1|(NBCI ENTREZ)). No domains predicted. No TMHs. Signal peptide present; Conserved hypothetical protein.
       0.581
lhpp
Phospholysine phosphohistidine inorganic pyrophosphate phosphatase. Enzyme that hydrolyzes not only oxygen-phosphorus bonds in inorganic pyrophosphate but also nitrogen-phosphorus bonds in phospholysine,phosphohistidine and imidodiphosphate in vitro. 38% HAD_SF_IIA.IPR006355; HAD_SF_IIA_hyp2.IPR005834; Hydrolase. Pfam:PF00702;Hydrolase; 1. TIGRFAMs:TIGR01460; HAD-SF-IIA; 1.TIGR01458; HAD-SF-IIA-hyp3; 1. TMHelix:1; High confidence in function and specificity.
 
  
  0.572
azo2851
Conserved hypothetical glycerophosphoryl diester phosphodiesterase. Homology to TdenA01001091 of Thiobacillus denitrificans of 66% (gnl|keqq|mca:MCA1922(KEGG)).InterPro: Glycerophosphoryl diester phosphodiesterase (IPR004129). Pfam: Glycerophosphoryl diester phosphodiesterase. signal peptide. no TMHs.
     
 0.556
ispB
Octaprenyl-diphosphate synthase; Polyprenyl synthetase,82% identity to TrEMBL;Q5P1Y1. Has Pfam;PF00348, Polyprenyl synthetase.(IPR000092,Polyprenyl_synt)A variety of isoprenoid compounds are synthesized by various organisms. For example in eukaryotes the isoprenoid biosynthetic pathway is responsible for the synthesis of a variety of end products including cholesterol, dolichol, ubiquinone or coenzyme Q. In bacteria this pathway leads to the synthesis of isopentenyl tRNA, isoprenoid quinones, and sugar carrier lipids. Among the enzymes that participate in that pathway, are a number of [...]
     
 0.518
azo2099
Conserved hypothetical secreted protein. Homology to xac2776 of X. axonopodis of 50% (trembl|Q8PIW9). Pfam: DUF839 This family consists of several bacterial proteins of unknown function. signal peptide. no TMHs; Conserved hypothetical protein.
  
 
 0.506
azo1650
Putative phosphodiesterase protein; Probable Serine--pyruvate aminotransferase mitochondrial precursor (EC 2.6.1.51) (SPT) (Alanine--glyoxylate aminotransferase) (EC 2.6.1.44) (AGT). TREMBL:Q7P1E0:36% identity, 45% similarity This family consists of phosphodiesterases, including human plasma-cell membrane glycoprotein PC-1 / alkaline phosphodiesterase I / nucleotide pyrophosphatase (nppase). These enzymes catalyse the cleavage of phosphodiester and phosphosulphate bonds in NAD, deoxynucleotides and nucleotide sugars InterPro:IPR002591; Phosphodiest. Pfam:PF01663; Phosphodiest; bcpB: ph [...]
  
 
 0.504
Your Current Organism:
Azoarcus sp. BH72
NCBI taxonomy Id: 62928
Other names: A. sp. BH72
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