Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Co-expression
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[Homology]
Score
azo1015Probable transcriptional regulator, LysR family,; Family membership; Belongs to the LysR transcriptional regulatory family. (311 aa)    
Predicted Functional Partners:
lysR
Putative transcriptional regulator, LysR family,; Family membership; Belongs to the LysR transcriptional regulatory family.
  
     0.728
azo3003
Conserved hypothetical transcriptional regulator,LysR family. Similar to SWISSPROT: sprot|NTCB_SYNP7 (18% Synechococcus sp. (strain PCC 7942) (Anacystis nidulans R2), nitrogen assimilation transcriptional activator NtcB) Pfam: PF00126 Bacterial regulatory helix-turn-helix protein, lysR family. HTH reporting nucleic acid binding motif; Family membership.
  
     0.645
azo1543
Transcriptional regulator, LysR family,; Specificity unclear; Belongs to the LysR transcriptional regulatory family.
  
     0.623
azo1835
Transcriptional regulator, LysR family,; Specificity unclear; Belongs to the LysR transcriptional regulatory family.
  
     0.622
nac
Nitrogen assimilation regulatory protein nac (Nitrogen assimilation control protein). TRANSCRIPTIONAL ACTIVATOR FOR THE HUT PUT AND URE OPERONS AND REPRESSOR FOR THE GDH AND GLTB OPERONS IN RESPONSE TO NITROGEN LIMITATION. NEGATIVE REGULATOR OF ITS OWN EXPRESSION. Similar to SWISSPROT: sprot|NAC_KLEAE (30% Klebsiella aerogenes, nitrogen assimilation regulatory protein nac (nitrogen assimilation control protein)) Pfam: PF00126 Bacterial regulatory helix-turn-helix protein, lysR family. HTH reporting nucleic acid binding motif; Specificity unclear.
  
     0.595
rbcR
Trans-acting transcriptional regulator of RuBisCO genes expression Putative HTH-type transcriptional regulator Contains 1 HTH lysR-type DNA-binding domain,belonds to the LysR family InterPro: Bacterial regulatory protein LysR family ModE_repress: ModE molybdate transport 32% HTH_LysR. IPR005119; LysR_subst. IPR009058; Wing_hlx_DNA_bnd. PF00126; HTH_1; 1. PF03466; LysR_substrate; 1; High confidence in function and specificity.
  
     0.565
lldA
L-lactate dehydrogenase. Homology to lldA of N. meningitidis of 72% (trembl|Q51135). InterPro: FMN-dependent alpha-hydroxy acid dehydrogenases (IPR000262); Proteins binding FMN and related compounds core region (IPR003009 Pfam: FMN-dependent dehydrogenase no signal peptide no TMHs; High confidence in function and specificity.
       0.556
gltR
Probable transcriptional regulator, LysR family; HTH-type transcriptional regulator gltR. POSITIVE REGULATOR OF GLUTAMATE BIOSYNTHESIS (GLTAB GENES). NEGATIVELY REGULATES ITS OWN EXPRESSION. Similar to SWISSPROT: sprot|GLTR_BACSU (33% Bacillus subtilis, HTH-type transcriptional regulator GltR) InterPro: IPR000847 HTH_LysR. IPR009058 Winged helix DNA-binding. Pfam: PF00126 Bacterial regulatory helix-turn-helix protein,lysR family. HTH reporting nucleic acid binding motif; High confidence in function and specificity.
  
     0.545
azo2360
Transcriptional regulator, LysR family,; Specificity unclear; Belongs to the LysR transcriptional regulatory family.
  
     0.500
rpoA
DNA-directed RNA polymerase; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
   0.462
Your Current Organism:
Azoarcus sp. BH72
NCBI taxonomy Id: 62928
Other names: A. sp. BH72
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