STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
phbFConserved hypothetical protein; phbF protein, 57% identity to TrEMBL;Q7NYA7. Has 2 copies of PF05233, PHB accumulation regulatory domain;IPR007897, PHB_accumulat: The proteins this domain is found in are typically involved in regulating polymer accumulation in bacteria, particularly poly-beta-hydroxybutyrate (PHB); High confidence in function and specificity. (209 aa)    
Predicted Functional Partners:
phaC
Probable polyhydroxyalkanoate synthase; Entry name :- TREMBL:Q9ZB54 Prim. accession # Q9ZB54 Identities = 290/560 (51%) InterPro:- IPR000073; A/b_hydrolase. IPR010941; PhaC_N. Pfam:- PF00561; Abhydrolase_1; 1. PF07167; PhaC_N; 1. Prediction: Signal peptide Signal peptide probability: 0.999 Number of predicted TMHs: 0; Family membership.
 
   
 0.825
phbC2
Probable poly-beta-hydroxybutyrate synthase; FUNCTION: Polymerizes d(-)-3-hydroxybutyryl-CoA to create PHB which consists of thousands of hydroxybutyrate molecules linked end to end. PHB serves as an intracellular energy reserve material when cells grow under conditions of nutrient limitation. Entry name :-PHBC_AZOCA Primary accession number:- O66392 Identity:-41% InterPro :-IPR000073; A/b_hydrolase. Pfam:- PF07167; PhaC_N; 1. Signal peptide probability: 0.000 Number of predicted TMHs: 0; Family membership.
 
   
 0.767
phbC1
Probable poly-beta-hydroxybutyrate synthase; Function:-Polymerizes d(-)-3-hydroxybutyryl-CoA to create PHB which consists of thousands of hydroxybutyrate molecules linked end to end. PHB serves as an intracellular energy reserve material when cells grow under conditions of nutrient limitation. Entry name TREMBL:Q8KXD5 Prim. accession # Q8KXD5 Identities = 354/607 (58%) InterPro IPR000073; A/b_hydrolase. IPR010941; PhaC_N. Pfam PF00561; Abhydrolase_1; 1. PF07167; PhaC_N; 1. Number of predicted TMHs: 0; High confidence in function and specificity.
 
   
 0.726
azo3815
Probable phasin. Homology to p8 of Sphingomonas sp. A1 of 49% (gi|51773776|dbj|BAD38885.1|(NBCI ENTREZ)). No domains predicted. No TMHs. No signal peptide.,; Function unclear.
 
   
 0.680
azo0789
Probable phasin. Homology to p8 of Sphingomonas sp. A1 of 69% (gi|51773776|dbj|BAD38885.1|(NBCI ENTREZ)). No domains predicted. No TMHs. No signal peptide; Family membership.
 
   
 0.666
rimO
Hypothetical protein; Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12; Belongs to the methylthiotransferase family. RimO subfamily.
       0.655
phbB2
The short-chain dehydrogenases/reductases family (SDR) is a very large family of enzymes, most of which are known to be NAD- or NADP-dependent oxidoreductases,SWISSPROT:P14697 (62% identity); TREMBL:Q8XYX3 (62% identiy). InterPro (IPR002198): Short-chain dehydrogenase/reductase (SDR). InterPro (IPR002347): Glucose/ribitol dehydrogenase. Pfam (PF00106): Short chain dehydrogenase. SignalP reporting signal peptide; High confidence in function and specificity.
 
   
 0.615
phbB1
The short-chain dehydrogenases/reductases family (SDR) is a very large family of enzymes, most of which are known to be NAD- or NADP-dependent oxidoreductases,SWISSPROT:P14697 (60% identity); TREMBL:Q8XYX3 (59% identity). Pfam (PF00106): Short chain dehydrogenase; High confidence in function and specificity.
 
   
 0.607
azo3439
Conserved hypothetical protein. Homology to ebB122 of Azoarcus sp. EbN1 of 65% (gnl|keqq|eba:ebB122(KEGG)). No domains predicted. NO signal peptide present. No TMH present.
  
     0.503
ychK
Probable esterase; Hypothetical protein ychK. TREMBL:Q89IT4: 42% identity, 58% similarity InterPro: Uncharacterized protein family UPF0028 InterPro:IPR002641; Patatin. Pfam:PF01734; Patatin hypA: hydrogenase expression/formation Non-secretory protein with signalpeptide probability:0.141 (SignalP predicted) Absence of TMH's; Family membership.
       0.432
Your Current Organism:
Azoarcus sp. BH72
NCBI taxonomy Id: 62928
Other names: A. sp. BH72
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