STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
azo1037Putative transport protein. Similarity to sugar transporters (lacY): lactose permease 2A0105.Similar to POT family of proteins with DUF domains and 12 transmembrane helices. 31% identity and 47% similarity to putative MFS metabolite transporter from Pseudomonas aeruginosa PA01; Family membership. (396 aa)    
Predicted Functional Partners:
aroC
AroC protein; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
     
 0.804
azo1038
Conserved hypothetical secreted protein. Homology to bb2112 of B. bronchiseptica of 55% (trembl|Q7WKJ4). Pfam: Peptidase family M48 signal peptide no TMHs; Conserved hypothetical protein.
       0.772
azo2636
Putative CbbY family protein; TREMBL:Q7MF75: 35% identity; 50% similarity. IPR006323; Phosphonoacetaldehyde hydrolase IPR010976; Beta-phosphoglucomutase hydrolase This group of sequences represent part of one structural subfamily of the Haloacid Dehalogenase (HAD) superfamily of aspartate-nucleophile hydrolases (IPR005834). The superfamily is defined by the presence of three short catalytic motifs. Hypothetical protein yhcW. InterPro:IPR006402; HAD-SF-IA-v3. IPR005833; Halogease/hydrolase. Pfam: PF00702; Hydrolase Absence of signal peptide (Signal P predicted) and transmembrane helices [...]
  
  
 0.697
leuC
LeuC protein; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate.
       0.590
leuD
LeuD protein; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. Belongs to the LeuD family. LeuD type 1 subfamily.
       0.543
ilvB
Acetolactate synthase isozyme I large subunit (AHAS-I) (Acetohydroxy-acid synthase I large subunit) (ALS-I). InterPro: Acetolactate synthase large subunit biosynthetic type acolac_lg: acetolactate synthase large subunit,biosynthetic type; High confidence in function and specificity.
       0.512
ilvN
Acetolactate synthase isozyme I small subunit (EC 2.2.1.6) (AHAS-I) (Acetohydroxy-acid synthase I small subunit) (ALS-I). InterPro: Acetolactate synthase small subunit acolac_sm: acetolactate synthase small subunit; High confidence in function and specificity.
       0.512
leuB
3-isopropylmalate dehydrogenase; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.
       0.458
azo1411
Conserved hypothetical ribonucleoside reductase; Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen.
    
  0.425
ndk
Nucleoside-diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family.
    
  0.421
Your Current Organism:
Azoarcus sp. BH72
NCBI taxonomy Id: 62928
Other names: A. sp. BH72
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