| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| gltB | ilvA | azo3642 | azo0500 | Ferredoxin-dependent glutamate synthase,; Specificity unclear. | Probable threonine dehydratase; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA. | 0.690 |
| gltB | ilvB | azo3642 | azo1034 | Ferredoxin-dependent glutamate synthase,; Specificity unclear. | Acetolactate synthase isozyme I large subunit (AHAS-I) (Acetohydroxy-acid synthase I large subunit) (ALS-I). InterPro: Acetolactate synthase large subunit biosynthetic type acolac_lg: acetolactate synthase large subunit,biosynthetic type; High confidence in function and specificity. | 0.548 |
| gltB | ilvH | azo3642 | azo3155 | Ferredoxin-dependent glutamate synthase,; Specificity unclear. | Acetolactate synthase small subunit (AHAS) (Acetohydroxy-acid synthase small subunit) (ALS). InterPro: Acetolactate synthase small subunit TIGRFAM: acolac_sm: acetolactate synthase small subunit; High confidence in function and specificity. | 0.620 |
| gltB | ilvI | azo3642 | azo3154 | Ferredoxin-dependent glutamate synthase,; Specificity unclear. | Acetolactate synthase isozyme III large subunit (AHAS- III) (Acetohydroxy-acid synthase III large subunit) (ALS-III). InterPro: Acetolactate synthase large subunit biosynthetic type TIGRFAM: acolac_lg: acetolactate synthase large subunit, biosynthetic type; High confidence in function and specificity. | 0.548 |
| gltB | ilvN | azo3642 | azo1035 | Ferredoxin-dependent glutamate synthase,; Specificity unclear. | Acetolactate synthase isozyme I small subunit (EC 2.2.1.6) (AHAS-I) (Acetohydroxy-acid synthase I small subunit) (ALS-I). InterPro: Acetolactate synthase small subunit acolac_sm: acetolactate synthase small subunit; High confidence in function and specificity. | 0.620 |
| gltB | leuB | azo3642 | azo1041 | Ferredoxin-dependent glutamate synthase,; Specificity unclear. | 3-isopropylmalate dehydrogenase; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate. | 0.952 |
| gltB | leuC | azo3642 | azo1039 | Ferredoxin-dependent glutamate synthase,; Specificity unclear. | LeuC protein; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. | 0.721 |
| gltB | leuD | azo3642 | azo1040 | Ferredoxin-dependent glutamate synthase,; Specificity unclear. | LeuD protein; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. Belongs to the LeuD family. LeuD type 1 subfamily. | 0.673 |
| gltB | lpdA | azo3642 | azo1371 | Ferredoxin-dependent glutamate synthase,; Specificity unclear. | Dihydrolipoamide dehydrogenase. Homology to lpdA of N. meningitides of 70% (trembl|Q59099). THE BRANCHED-CHAIN ALPHA-KETO DEHYDROGENASE COMPLEX CATALYZES THE OVERALL CONVERSION OF ALPHA-KETO ACIDS TO ACYL-COA AND CO(2). IT CONTAINS MULTIPLE COPIES OF 3 ENZYMATIC COMPONENTS: BRANCHED-CHAIN ALPHA-KETO ACID DECARBOXYLASE (E1) LIPOAMIDE ACYLTRANSFERASE (E2) AND LIPOAMIDE DEHYDROGENASE (E3) (BY SIMILARITY). InterPro: FAD-dependent pyridine nucleotide-disulphide oxidoreductase (IPR001327); Pyridine nucleotide-disulphide oxidoreductase, classI (IPR001100); biotin/Lipoyl attachment (IPR000089) [...] | 0.946 |
| gltB | sucD | azo3642 | azo3332 | Ferredoxin-dependent glutamate synthase,; Specificity unclear. | Probable succinyl-CoA synthetase, alpha chain; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. | 0.947 |
| ilvA | gltB | azo0500 | azo3642 | Probable threonine dehydratase; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA. | Ferredoxin-dependent glutamate synthase,; Specificity unclear. | 0.690 |
| ilvA | ilvB | azo0500 | azo1034 | Probable threonine dehydratase; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA. | Acetolactate synthase isozyme I large subunit (AHAS-I) (Acetohydroxy-acid synthase I large subunit) (ALS-I). InterPro: Acetolactate synthase large subunit biosynthetic type acolac_lg: acetolactate synthase large subunit,biosynthetic type; High confidence in function and specificity. | 0.964 |
| ilvA | ilvH | azo0500 | azo3155 | Probable threonine dehydratase; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA. | Acetolactate synthase small subunit (AHAS) (Acetohydroxy-acid synthase small subunit) (ALS). InterPro: Acetolactate synthase small subunit TIGRFAM: acolac_sm: acetolactate synthase small subunit; High confidence in function and specificity. | 0.974 |
| ilvA | ilvI | azo0500 | azo3154 | Probable threonine dehydratase; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA. | Acetolactate synthase isozyme III large subunit (AHAS- III) (Acetohydroxy-acid synthase III large subunit) (ALS-III). InterPro: Acetolactate synthase large subunit biosynthetic type TIGRFAM: acolac_lg: acetolactate synthase large subunit, biosynthetic type; High confidence in function and specificity. | 0.959 |
| ilvA | ilvN | azo0500 | azo1035 | Probable threonine dehydratase; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA. | Acetolactate synthase isozyme I small subunit (EC 2.2.1.6) (AHAS-I) (Acetohydroxy-acid synthase I small subunit) (ALS-I). InterPro: Acetolactate synthase small subunit acolac_sm: acetolactate synthase small subunit; High confidence in function and specificity. | 0.929 |
| ilvA | leuB | azo0500 | azo1041 | Probable threonine dehydratase; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA. | 3-isopropylmalate dehydrogenase; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate. | 0.932 |
| ilvA | leuC | azo0500 | azo1039 | Probable threonine dehydratase; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA. | LeuC protein; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. | 0.616 |
| ilvA | leuD | azo0500 | azo1040 | Probable threonine dehydratase; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA. | LeuD protein; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. Belongs to the LeuD family. LeuD type 1 subfamily. | 0.646 |
| ilvA | lpdA | azo0500 | azo1371 | Probable threonine dehydratase; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA. | Dihydrolipoamide dehydrogenase. Homology to lpdA of N. meningitides of 70% (trembl|Q59099). THE BRANCHED-CHAIN ALPHA-KETO DEHYDROGENASE COMPLEX CATALYZES THE OVERALL CONVERSION OF ALPHA-KETO ACIDS TO ACYL-COA AND CO(2). IT CONTAINS MULTIPLE COPIES OF 3 ENZYMATIC COMPONENTS: BRANCHED-CHAIN ALPHA-KETO ACID DECARBOXYLASE (E1) LIPOAMIDE ACYLTRANSFERASE (E2) AND LIPOAMIDE DEHYDROGENASE (E3) (BY SIMILARITY). InterPro: FAD-dependent pyridine nucleotide-disulphide oxidoreductase (IPR001327); Pyridine nucleotide-disulphide oxidoreductase, classI (IPR001100); biotin/Lipoyl attachment (IPR000089) [...] | 0.550 |
| ilvB | gltB | azo1034 | azo3642 | Acetolactate synthase isozyme I large subunit (AHAS-I) (Acetohydroxy-acid synthase I large subunit) (ALS-I). InterPro: Acetolactate synthase large subunit biosynthetic type acolac_lg: acetolactate synthase large subunit,biosynthetic type; High confidence in function and specificity. | Ferredoxin-dependent glutamate synthase,; Specificity unclear. | 0.548 |
