| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| azo0400 | azo0401 | azo0400 | azo0401 | Conserved hypothetical membrane protein. Homology to TP1032 of Treponema pallidum of 32% (sprot|YA32_TREPA(SRS)). Has PF07009(IPR010739):Protein of unknown function (DUF1312);This family consists of several bacterial proteins of around 120 residues in length. The function of this family is unknown. No singal peptide. 1 TMH; Conserved hypothetical protein. | Heptaprenyl diphosphate synthase component I, 23% identity (45% similarity) to TrEMBL;Q896H9. Has PF07456,Heptaprenyl diphosphate synthase component I;IPR010898,Hpre_diP_synt_I: This family contains component I of bacterial heptaprenyl diphosphate synthase (approximately 170 residues long). This is one of the two dissociable subunits that form the enzyme, both of which are required for the catalysis of the biosynthesis of the side chain of menaquinone-7. | 0.986 |
| azo0400 | azo1044 | azo0400 | azo1044 | Conserved hypothetical membrane protein. Homology to TP1032 of Treponema pallidum of 32% (sprot|YA32_TREPA(SRS)). Has PF07009(IPR010739):Protein of unknown function (DUF1312);This family consists of several bacterial proteins of around 120 residues in length. The function of this family is unknown. No singal peptide. 1 TMH; Conserved hypothetical protein. | Conserved hypothetical membrane protein. Homology to ebA4769 of Azoarcus sp. EbN1 of 53% (gnl|keqq|eba:ebA4769(KEGG)). Pfam: Cobalt transport protein. signal peptide. 3 TMHs; Family membership. | 0.763 |
| azo0401 | azo0400 | azo0401 | azo0400 | Heptaprenyl diphosphate synthase component I, 23% identity (45% similarity) to TrEMBL;Q896H9. Has PF07456,Heptaprenyl diphosphate synthase component I;IPR010898,Hpre_diP_synt_I: This family contains component I of bacterial heptaprenyl diphosphate synthase (approximately 170 residues long). This is one of the two dissociable subunits that form the enzyme, both of which are required for the catalysis of the biosynthesis of the side chain of menaquinone-7. | Conserved hypothetical membrane protein. Homology to TP1032 of Treponema pallidum of 32% (sprot|YA32_TREPA(SRS)). Has PF07009(IPR010739):Protein of unknown function (DUF1312);This family consists of several bacterial proteins of around 120 residues in length. The function of this family is unknown. No singal peptide. 1 TMH; Conserved hypothetical protein. | 0.986 |
| azo0401 | azo1044 | azo0401 | azo1044 | Heptaprenyl diphosphate synthase component I, 23% identity (45% similarity) to TrEMBL;Q896H9. Has PF07456,Heptaprenyl diphosphate synthase component I;IPR010898,Hpre_diP_synt_I: This family contains component I of bacterial heptaprenyl diphosphate synthase (approximately 170 residues long). This is one of the two dissociable subunits that form the enzyme, both of which are required for the catalysis of the biosynthesis of the side chain of menaquinone-7. | Conserved hypothetical membrane protein. Homology to ebA4769 of Azoarcus sp. EbN1 of 53% (gnl|keqq|eba:ebA4769(KEGG)). Pfam: Cobalt transport protein. signal peptide. 3 TMHs; Family membership. | 0.811 |
| azo1044 | azo0400 | azo1044 | azo0400 | Conserved hypothetical membrane protein. Homology to ebA4769 of Azoarcus sp. EbN1 of 53% (gnl|keqq|eba:ebA4769(KEGG)). Pfam: Cobalt transport protein. signal peptide. 3 TMHs; Family membership. | Conserved hypothetical membrane protein. Homology to TP1032 of Treponema pallidum of 32% (sprot|YA32_TREPA(SRS)). Has PF07009(IPR010739):Protein of unknown function (DUF1312);This family consists of several bacterial proteins of around 120 residues in length. The function of this family is unknown. No singal peptide. 1 TMH; Conserved hypothetical protein. | 0.763 |
| azo1044 | azo0401 | azo1044 | azo0401 | Conserved hypothetical membrane protein. Homology to ebA4769 of Azoarcus sp. EbN1 of 53% (gnl|keqq|eba:ebA4769(KEGG)). Pfam: Cobalt transport protein. signal peptide. 3 TMHs; Family membership. | Heptaprenyl diphosphate synthase component I, 23% identity (45% similarity) to TrEMBL;Q896H9. Has PF07456,Heptaprenyl diphosphate synthase component I;IPR010898,Hpre_diP_synt_I: This family contains component I of bacterial heptaprenyl diphosphate synthase (approximately 170 residues long). This is one of the two dissociable subunits that form the enzyme, both of which are required for the catalysis of the biosynthesis of the side chain of menaquinone-7. | 0.811 |
| azo1044 | azo3528 | azo1044 | azo3528 | Conserved hypothetical membrane protein. Homology to ebA4769 of Azoarcus sp. EbN1 of 53% (gnl|keqq|eba:ebA4769(KEGG)). Pfam: Cobalt transport protein. signal peptide. 3 TMHs; Family membership. | Conserved hypothetical membrane protein. Homology to blr3274 of B. japonicum of 33% (gnl|keqq|bja:blr3274(KEGG)). Pfam: weak hit to CbiM, an integral membrane protein involved in cobalamin synthesis. TMHMM reporting 5 transmembrane helices. No signal peptide; Conserved hypothetical protein. | 0.937 |
| azo1044 | cbiM | azo1044 | azo2220 | Conserved hypothetical membrane protein. Homology to ebA4769 of Azoarcus sp. EbN1 of 53% (gnl|keqq|eba:ebA4769(KEGG)). Pfam: Cobalt transport protein. signal peptide. 3 TMHs; Family membership. | Putative cobalt transport system, permease protein; Part of the ABC transporter complex cbiKMQO involved in cobalt import. Similar to the cobalt transport membrane protein, CbiM in A. pleuropneumoniae. InterPro: Cobalamin synthesis CBIM cbiM: cobalamin biosynthesis protein Cbi; High confidence in function and specificity. | 0.937 |
| azo1044 | cbiO | azo1044 | azo2222 | Conserved hypothetical membrane protein. Homology to ebA4769 of Azoarcus sp. EbN1 of 53% (gnl|keqq|eba:ebA4769(KEGG)). Pfam: Cobalt transport protein. signal peptide. 3 TMHs; Family membership. | Putative cobalt transport system ATP-binding protein; Part of the ABC transporter complex cbiKMQO involved in cobalt import. Probably responsible for the translocation of the substrate across the membrane. 40% AAA_ATPase.IPR003439; ABC_transporter. Pfam:PF00005; ABC_tran; 1. ProDom; PD000006; ABC_transporter; 1. SMART; SM00382; AAA; 1; High confidence in function and specificity. | 0.979 |
| azo1044 | dppD | azo1044 | azo0221 | Conserved hypothetical membrane protein. Homology to ebA4769 of Azoarcus sp. EbN1 of 53% (gnl|keqq|eba:ebA4769(KEGG)). Pfam: Cobalt transport protein. signal peptide. 3 TMHs; Family membership. | Putative dipeptide transport system, ATP-binding protein; Part of the ABC transporter complex dppABCD involved in dipeptide import. Similar to the dipeptide transport membrane protein, DppD in E.coli Probably responsible for energy coupling to the transport system; Specificity unclear. | 0.910 |
| azo1044 | dppF | azo1044 | azo2061 | Conserved hypothetical membrane protein. Homology to ebA4769 of Azoarcus sp. EbN1 of 53% (gnl|keqq|eba:ebA4769(KEGG)). Pfam: Cobalt transport protein. signal peptide. 3 TMHs; Family membership. | Hypothetical ABC transporter ATP-binding protein yliA. PROBABLY PART OF A BINDING-PROTEIN-DEPENDENT TRANSPORT SYSTEM YLIABCD. PROBABLY RESPONSIBLE FOR ENERGY COUPLING TO THE TRANSPORT SYSTEM. TREMBL:Q82S74: 52% identity, 64% similarity. InterPro: IPR003593; AAA_ATPase. No signal peptide No transmembrane helices. IPR003439; ABC_transporter. IPR010066; Oligo_HPY. Pfam:PF00005; ABC_tran; 2. ProDom: PD000006; ABC_transporter; 1. SMART:SM00382; AAA; 2. TIGRFAMs TIGR01727; oligo_HPY mobB: molybdopterin-guanine dinucleotid; High confidence in function and specificity. | 0.910 |
| azo1044 | trpB | azo1044 | azo1047 | Conserved hypothetical membrane protein. Homology to ebA4769 of Azoarcus sp. EbN1 of 53% (gnl|keqq|eba:ebA4769(KEGG)). Pfam: Cobalt transport protein. signal peptide. 3 TMHs; Family membership. | TrpB protein; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. | 0.810 |
| azo1044 | trpF | azo1044 | azo1046 | Conserved hypothetical membrane protein. Homology to ebA4769 of Azoarcus sp. EbN1 of 53% (gnl|keqq|eba:ebA4769(KEGG)). Pfam: Cobalt transport protein. signal peptide. 3 TMHs; Family membership. | N-(5-phosphoribosyl)anthranilate isomerase (PRAI) catalyzes the third step of tryptophan biosynthesis. Similar to sprot|TRPF_RALSO (56%) and to sprot|TRPF_PSEAE (58%). Pfam (PF00697): N-(5'phosphoribosyl)anthranilate isomerase (PRAI); High confidence in function and specificity. | 0.840 |
| azo1044 | truA | azo1044 | azo1045 | Conserved hypothetical membrane protein. Homology to ebA4769 of Azoarcus sp. EbN1 of 53% (gnl|keqq|eba:ebA4769(KEGG)). Pfam: Cobalt transport protein. signal peptide. 3 TMHs; Family membership. | Pseudouridine synthase A; Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs. | 0.930 |
| azo3528 | azo1044 | azo3528 | azo1044 | Conserved hypothetical membrane protein. Homology to blr3274 of B. japonicum of 33% (gnl|keqq|bja:blr3274(KEGG)). Pfam: weak hit to CbiM, an integral membrane protein involved in cobalamin synthesis. TMHMM reporting 5 transmembrane helices. No signal peptide; Conserved hypothetical protein. | Conserved hypothetical membrane protein. Homology to ebA4769 of Azoarcus sp. EbN1 of 53% (gnl|keqq|eba:ebA4769(KEGG)). Pfam: Cobalt transport protein. signal peptide. 3 TMHs; Family membership. | 0.937 |
| azo3528 | cbiO | azo3528 | azo2222 | Conserved hypothetical membrane protein. Homology to blr3274 of B. japonicum of 33% (gnl|keqq|bja:blr3274(KEGG)). Pfam: weak hit to CbiM, an integral membrane protein involved in cobalamin synthesis. TMHMM reporting 5 transmembrane helices. No signal peptide; Conserved hypothetical protein. | Putative cobalt transport system ATP-binding protein; Part of the ABC transporter complex cbiKMQO involved in cobalt import. Probably responsible for the translocation of the substrate across the membrane. 40% AAA_ATPase.IPR003439; ABC_transporter. Pfam:PF00005; ABC_tran; 1. ProDom; PD000006; ABC_transporter; 1. SMART; SM00382; AAA; 1; High confidence in function and specificity. | 0.925 |
| cbiM | azo1044 | azo2220 | azo1044 | Putative cobalt transport system, permease protein; Part of the ABC transporter complex cbiKMQO involved in cobalt import. Similar to the cobalt transport membrane protein, CbiM in A. pleuropneumoniae. InterPro: Cobalamin synthesis CBIM cbiM: cobalamin biosynthesis protein Cbi; High confidence in function and specificity. | Conserved hypothetical membrane protein. Homology to ebA4769 of Azoarcus sp. EbN1 of 53% (gnl|keqq|eba:ebA4769(KEGG)). Pfam: Cobalt transport protein. signal peptide. 3 TMHs; Family membership. | 0.937 |
| cbiM | cbiO | azo2220 | azo2222 | Putative cobalt transport system, permease protein; Part of the ABC transporter complex cbiKMQO involved in cobalt import. Similar to the cobalt transport membrane protein, CbiM in A. pleuropneumoniae. InterPro: Cobalamin synthesis CBIM cbiM: cobalamin biosynthesis protein Cbi; High confidence in function and specificity. | Putative cobalt transport system ATP-binding protein; Part of the ABC transporter complex cbiKMQO involved in cobalt import. Probably responsible for the translocation of the substrate across the membrane. 40% AAA_ATPase.IPR003439; ABC_transporter. Pfam:PF00005; ABC_tran; 1. ProDom; PD000006; ABC_transporter; 1. SMART; SM00382; AAA; 1; High confidence in function and specificity. | 0.992 |
| cbiO | azo1044 | azo2222 | azo1044 | Putative cobalt transport system ATP-binding protein; Part of the ABC transporter complex cbiKMQO involved in cobalt import. Probably responsible for the translocation of the substrate across the membrane. 40% AAA_ATPase.IPR003439; ABC_transporter. Pfam:PF00005; ABC_tran; 1. ProDom; PD000006; ABC_transporter; 1. SMART; SM00382; AAA; 1; High confidence in function and specificity. | Conserved hypothetical membrane protein. Homology to ebA4769 of Azoarcus sp. EbN1 of 53% (gnl|keqq|eba:ebA4769(KEGG)). Pfam: Cobalt transport protein. signal peptide. 3 TMHs; Family membership. | 0.979 |
| cbiO | azo3528 | azo2222 | azo3528 | Putative cobalt transport system ATP-binding protein; Part of the ABC transporter complex cbiKMQO involved in cobalt import. Probably responsible for the translocation of the substrate across the membrane. 40% AAA_ATPase.IPR003439; ABC_transporter. Pfam:PF00005; ABC_tran; 1. ProDom; PD000006; ABC_transporter; 1. SMART; SM00382; AAA; 1; High confidence in function and specificity. | Conserved hypothetical membrane protein. Homology to blr3274 of B. japonicum of 33% (gnl|keqq|bja:blr3274(KEGG)). Pfam: weak hit to CbiM, an integral membrane protein involved in cobalamin synthesis. TMHMM reporting 5 transmembrane helices. No signal peptide; Conserved hypothetical protein. | 0.925 |