STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
azo1044Conserved hypothetical membrane protein. Homology to ebA4769 of Azoarcus sp. EbN1 of 53% (gnl|keqq|eba:ebA4769(KEGG)). Pfam: Cobalt transport protein. signal peptide. 3 TMHs; Family membership. (203 aa)    
Predicted Functional Partners:
cbiO
Putative cobalt transport system ATP-binding protein; Part of the ABC transporter complex cbiKMQO involved in cobalt import. Probably responsible for the translocation of the substrate across the membrane. 40% AAA_ATPase.IPR003439; ABC_transporter. Pfam:PF00005; ABC_tran; 1. ProDom; PD000006; ABC_transporter; 1. SMART; SM00382; AAA; 1; High confidence in function and specificity.
  
 0.981
dppD
Putative dipeptide transport system, ATP-binding protein; Part of the ABC transporter complex dppABCD involved in dipeptide import. Similar to the dipeptide transport membrane protein, DppD in E.coli Probably responsible for energy coupling to the transport system; Specificity unclear.
  
 0.952
dppF
Hypothetical ABC transporter ATP-binding protein yliA. PROBABLY PART OF A BINDING-PROTEIN-DEPENDENT TRANSPORT SYSTEM YLIABCD. PROBABLY RESPONSIBLE FOR ENERGY COUPLING TO THE TRANSPORT SYSTEM. TREMBL:Q82S74: 52% identity, 64% similarity. InterPro: IPR003593; AAA_ATPase. No signal peptide No transmembrane helices. IPR003439; ABC_transporter. IPR010066; Oligo_HPY. Pfam:PF00005; ABC_tran; 2. ProDom: PD000006; ABC_transporter; 1. SMART:SM00382; AAA; 2. TIGRFAMs TIGR01727; oligo_HPY mobB: molybdopterin-guanine dinucleotid; High confidence in function and specificity.
  
 0.952
truA
Pseudouridine synthase A; Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
  
  
 0.897
cbiM
Putative cobalt transport system, permease protein; Part of the ABC transporter complex cbiKMQO involved in cobalt import. Similar to the cobalt transport membrane protein, CbiM in A. pleuropneumoniae. InterPro: Cobalamin synthesis CBIM cbiM: cobalamin biosynthesis protein Cbi; High confidence in function and specificity.
  
 
 0.896
azo3528
Conserved hypothetical membrane protein. Homology to blr3274 of B. japonicum of 33% (gnl|keqq|bja:blr3274(KEGG)). Pfam: weak hit to CbiM, an integral membrane protein involved in cobalamin synthesis. TMHMM reporting 5 transmembrane helices. No signal peptide; Conserved hypothetical protein.
  
 
 0.896
azo2910
ATP-binding cassette (ABC) transporters form a large family of proteins responsible for translocation of a variety of compounds across biological membranes. They are composed of two transmembrane domains responsible for binding and transport and two nucleotide-binding domains responsible for coupling the energy of ATP hydrolysis to conformational changes in the TMDs, TREMBL:Q8FZX0 (58% identity); TREMBL:Q8U6Y9 (59% identity). InterPro (IPR003593): AAA ATPase. InterPro (IPR001687): ATP/GTP-binding site motif A (P-loop). InterPro (IPR003439): ABC transporter. Pfam (PF00005): ABC transpor [...]
    
 0.827
trpF
N-(5-phosphoribosyl)anthranilate isomerase (PRAI) catalyzes the third step of tryptophan biosynthesis. Similar to sprot|TRPF_RALSO (56%) and to sprot|TRPF_PSEAE (58%). Pfam (PF00697): N-(5'phosphoribosyl)anthranilate isomerase (PRAI); High confidence in function and specificity.
       0.826
trpB
TrpB protein; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine.
       0.799
ugpB
Glycerol-3-phosphate-binding periplasmic protein precursor. SN-glycerol-3-phosphate and glycerophosphoryl diester-binding protein interacts with the binding protein-dependent transport system ugpACE. 30% SBP_bac_1.IPR006061; SBP_dom1. Pfam:PF01547; SBP_bac_1; 1. Signal peptide:present; High confidence in function and specificity.
  
  
  0.780
Your Current Organism:
Azoarcus sp. BH72
NCBI taxonomy Id: 62928
Other names: A. sp. BH72
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