STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
truAPseudouridine synthase A; Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs. (265 aa)    
Predicted Functional Partners:
azo1044
Conserved hypothetical membrane protein. Homology to ebA4769 of Azoarcus sp. EbN1 of 53% (gnl|keqq|eba:ebA4769(KEGG)). Pfam: Cobalt transport protein. signal peptide. 3 TMHs; Family membership.
  
  
 0.930
rpoA
DNA-directed RNA polymerase; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
  
  
 0.910
trpF
N-(5-phosphoribosyl)anthranilate isomerase (PRAI) catalyzes the third step of tryptophan biosynthesis. Similar to sprot|TRPF_RALSO (56%) and to sprot|TRPF_PSEAE (58%). Pfam (PF00697): N-(5'phosphoribosyl)anthranilate isomerase (PRAI); High confidence in function and specificity.
     
 0.895
rplQ
50S ribosomal protein L17; High confidence in function and specificity.
  
  
 0.879
trpB
TrpB protein; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine.
     
 0.859
ybeY
Conserved hypothetical protein; Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.
  
   0.838
folC
Dihydrofolate synthase / Tetrahydrofolylpolyglutamate synthase; FolC bifunctional protein [Includes: Folylpolyglutamate synthase (EC 6.3.2.17) (Folylpoly-gamma-glutamate synthetase) (FPGS); Dihydrofolate synthase (EC 6.3.2.12)]. Conversion of folates to polyglutamate derivatives; High confidence in function and specificity.
 
   
 0.832
mraW
SAM dependent methyltransferase; Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.
   
 
 0.830
fimV1
Putative type 4 pilus biogenesis; In Pseudomonas aeruginosa, FimV ist probable involved in remodelling of the peptidoglycan layer to enable assembly of the type IV fimbrial structure and machinery. And it is also required for twitching motility. Similar to trembl|O87015 (28%). Pfam (PF01476): LysM domain Pfam (PF04102): SlyX, may be a coiled-coil structure SignalP reporting Signal peptide; Function unclear.
  
  
 0.821
trpA
TrpA protein; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family.
     
 0.798
Your Current Organism:
Azoarcus sp. BH72
NCBI taxonomy Id: 62928
Other names: A. sp. BH72
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