STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
azo1051Conserved hypothetical membrane proteine. Homology to BB2598 of Bordetella bronchiseptica of 37% (trembl|Q7WJA1(SRS)). Has 2 copies of PF05036, Sporulation related repeat;IPR007730, SPOR; This 35 residue repeat is found in proteins involved in sporulation and cell division such as FtsN, DedD, and CwlM. This repeat might be involved in binding peptidoglycan (Bateman A pers obs). FtsN is an essential cell division protein with a simple bitopic topology, a short N-terminal cytoplasmic segment fused to a large carboxy periplasmic domain through a single transmembrane domain. These repeats [...] (213 aa)    
Predicted Functional Partners:
folC
Dihydrofolate synthase / Tetrahydrofolylpolyglutamate synthase; FolC bifunctional protein [Includes: Folylpolyglutamate synthase (EC 6.3.2.17) (Folylpoly-gamma-glutamate synthetase) (FPGS); Dihydrofolate synthase (EC 6.3.2.12)]. Conversion of folates to polyglutamate derivatives; High confidence in function and specificity.
  
    0.880
cvpA
Colicin V production protein (dedE protein) (Pur regulon 18 kDa protein). REQUIRED FOR COLICIN V PRODUCTION FROM PLASMID INCFI COLV3-K30. TREMBL:Q82WH7: 29% identity,38% similarity InterPro:IPR003825; Colicin_V. Pfam:PF02674; Colicin_V TIGR00304: conserved hypothetical protei Signal peptide present (Signal P predicted) TMH's 4 (TMHMM predicted); High confidence in function and specificity.
       0.826
purF
Amidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine; In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.
     
 0.812
metZ
Cys/Met metabolism pyridoxal-phosphate-dependent enzyme; Catalyzes the formation of L-homocysteine from O-succinyl-L- homoserine (OSHS) and hydrogen sulfide.
       0.779
accD
Probable acetyl-coenzyme A carboxylase carboxyl transferase subunit b; Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA; Belongs to the AccD/PCCB family.
  
    0.772
trpA
TrpA protein; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family.
       0.755
mreD
Rod shape-determining protein mreD. Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins; High confidence in function and specificity.
 
     0.673
fliA
RNA polymerase sigma factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor controls the expression of flagella-related genes; Belongs to the sigma-70 factor family. FliA subfamily.
   
 
 0.670
truA
Pseudouridine synthase A; Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
       0.650
trpF
N-(5-phosphoribosyl)anthranilate isomerase (PRAI) catalyzes the third step of tryptophan biosynthesis. Similar to sprot|TRPF_RALSO (56%) and to sprot|TRPF_PSEAE (58%). Pfam (PF00697): N-(5'phosphoribosyl)anthranilate isomerase (PRAI); High confidence in function and specificity.
       0.650
Your Current Organism:
Azoarcus sp. BH72
NCBI taxonomy Id: 62928
Other names: A. sp. BH72
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