Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
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experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
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[Homology]
Score
azo1058Conserved hypothetical secreted proteins. Homology to of Dechloromonas aromatica of 56% (gi|41723709|ref|ZP_00150619.1|(NBCI ENTREZ)). Signal Peptide Present. No TMH present. Has PF03734:(IPR005490)ErfK/YbiS/YcfS/YnhG;This family of proteins are found in a range of bacteria. The conserved region contains a conserved histidine and cysteine,suggesting that these proteins have an enzymatic activity. Several members of this family contain peptidoglycan binding domains. So these proteins may use peptidoglycan or a precursor as a substrate; Conserved hypothetical protein. (398 aa)    
Predicted Functional Partners:
azo1059
Conserved hypothetical secreted protein. Homology to Daro03002816 of Dechloromonas aromatica of 42% (gi|53730051|ref|ZP_00348646.1|(NBCI ENTREZ)). domain structure: 59 aa - 92 aa TRP; 93 aa- 126 aa TRP; 127 aa -155 aa TRP. InterPro: TPR repeat (IPR001440); Type I antifreeze protein (IPR000104). Pfam: TRP Domain. signal peptide. no TMHs; Conserved hypothetical protein.
 
     0.956
ppiA
Probable peptidyl-prolyl cis-trans isomerase A; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family.
       0.719
azo3329
Putative 3',5'-cyclic-nucleotide phosphodiesterase; Probable 35-cyclic-nucleotide phosphodiesterase precursor (EC 3.1.4.17) (PDEase) (3:5-CNP). TREMBL:Q8ZD92:28% identity, 47% similarity InterPro; IPR001279; Blactmase-like. IPR000396; Pdiesterase2. Pfam: PF00753; Lactamase_B No transmembrane helices TIGR00010: deoxyribonuclease TatD fami; Function unclear.
  
     0.698
fliL
Putative flagellar basal body-associated protein FliL; Controls the rotational direction of flagella during chemotaxis; Belongs to the FliL family.
  
 
   0.697
ppiB
Peptidyl-prolyl cis-trans isomerase B; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family.
       0.690
lpxH
Putative UDP-2,3-diacylglucosamine hydrolase; Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
       0.683
cysS
CysS protein; Cysteinyl-tRNA synthetase (EC 6.1.1.16) (Cysteine--tRNA ligase) (CysRS). InterPro: Cysteinyl-tRNA synthetase cysS: cysteinyl-tRNA synthetase; High confidence in function and specificity; Belongs to the class-I aminoacyl-tRNA synthetase family.
       0.604
azo0422
Hypothetical protein; SPROT:P37718: 26% identity, 43% similarity Cellulose synthase operon protein C precursor. Required for maximal bacterial cellulose synthesis. InterPro: STAS domain. The STAS (Sulphate Transporter and AntiSigma factor antagonist) domain is found in the C-terminal region of sulphate transporters and bacterial anti-sigma factor antagonists. It has been suggested that this domain may have a general NTP binding function. InterPro:IPR008410; BCSC_C. IPR003921; Cell_synth_C. Pfam:PF05420; BCSC_C; 1. ant_ant_sig: anti-anti-sigma factor No signal peptide present SignalP pr [...]
  
     0.590
azo3182
Conserved hypothetical protein. Homology to Daro03003801 of Dechloromonas aromatica of 44% (gi|41722610|ref|ZP_00149605.1|(NBCI ENTREZ)). No domains predicted. No signal peptide. No TMHs.
  
     0.577
azo2753
Conserved hypothetical protein. Homology to NE1501 of N.europaea of 47% (trembl:Q82UI4). No domains predicted. Signal peptide present. No TMH reported present.
  
     0.543
Your Current Organism:
Azoarcus sp. BH72
NCBI taxonomy Id: 62928
Other names: A. sp. BH72
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