node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
azo0358 | azo2661 | azo0358 | azo2661 | Putative two-component sensor kinase; Region start changed from 382943 to 383189 (246 bases). | Hypothetical protein which carries at the C-terminus a DnaJ N-terminal domain. InterPro: DnaJ N-terminal domain (IPR001623) Pfam: DnaJ domain no signal peptide no TMHs. | 0.981 |
azo0358 | clpA | azo0358 | azo1132 | Putative two-component sensor kinase; Region start changed from 382943 to 383189 (246 bases). | ATP-dependent Clp protease ATP-binding subunit clpA. Homology to clpA of E. coli of 63% (sprot|CLPA_ECOLI). ATP-dependent specificity component of the clpP protease. It directs the protease to specific substrates. The primary function of the clpA-clpP complex appears to be the degradation of unfolded or abnormal proteins. InterPro: AAA-protein (ATPases associated with various cellular activities)(IPR003959); AAA ATPase superfamily (IPR003593); Clp amino terminus (IPR004176); chaperonins clpA/B (IPR001270); Bacterial typeII secretion system protein E (IPR001482) Pfam: Clp amino ternimal [...] | 0.746 |
azo0358 | clpB1 | azo0358 | azo1566 | Putative two-component sensor kinase; Region start changed from 382943 to 383189 (246 bases). | Probable ATP-dependent Clp protease, ATP-binding subunit ClpB; Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE; Belongs to the ClpA/ClpB family. | 0.747 |
azo0358 | dnaJ1 | azo0358 | azo1062 | Putative two-component sensor kinase; Region start changed from 382943 to 383189 (246 bases). | Chaperone protein DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...] | 0.981 |
azo0358 | dnaJ2 | azo0358 | azo1266 | Putative two-component sensor kinase; Region start changed from 382943 to 383189 (246 bases). | Putative chaperone protein dnaJ. homology to dnaJ of E. coli of 32% (sprot|DNAJ_ECOLI) Acts as a co-chaperone. Stimulates jointly with grpE the ATPase activity of dnaK (By similarity). Pfam: DnaJ domain, DnaJ central domain (4 repeats), DnaJ Cterminal region no singal peptide no TMHs; Family membership. | 0.981 |
azo0358 | dnaK | azo0358 | azo1063 | Putative two-component sensor kinase; Region start changed from 382943 to 383189 (246 bases). | Chaperone protein DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family. | 0.987 |
azo0358 | groEL1 | azo0358 | azo0974 | Putative two-component sensor kinase; Region start changed from 382943 to 383189 (246 bases). | Chaperonin GroEL; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions. | 0.895 |
azo0358 | groEL3 | azo0358 | azo2366 | Putative two-component sensor kinase; Region start changed from 382943 to 383189 (246 bases). | Chaperonin GroEL; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions. | 0.895 |
azo0358 | grpE | azo0358 | azo1064 | Putative two-component sensor kinase; Region start changed from 382943 to 383189 (246 bases). | Probable heat shock protein GrpE; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several round [...] | 0.819 |
azo2661 | azo0358 | azo2661 | azo0358 | Hypothetical protein which carries at the C-terminus a DnaJ N-terminal domain. InterPro: DnaJ N-terminal domain (IPR001623) Pfam: DnaJ domain no signal peptide no TMHs. | Putative two-component sensor kinase; Region start changed from 382943 to 383189 (246 bases). | 0.981 |
azo2661 | clpA | azo2661 | azo1132 | Hypothetical protein which carries at the C-terminus a DnaJ N-terminal domain. InterPro: DnaJ N-terminal domain (IPR001623) Pfam: DnaJ domain no signal peptide no TMHs. | ATP-dependent Clp protease ATP-binding subunit clpA. Homology to clpA of E. coli of 63% (sprot|CLPA_ECOLI). ATP-dependent specificity component of the clpP protease. It directs the protease to specific substrates. The primary function of the clpA-clpP complex appears to be the degradation of unfolded or abnormal proteins. InterPro: AAA-protein (ATPases associated with various cellular activities)(IPR003959); AAA ATPase superfamily (IPR003593); Clp amino terminus (IPR004176); chaperonins clpA/B (IPR001270); Bacterial typeII secretion system protein E (IPR001482) Pfam: Clp amino ternimal [...] | 0.748 |
azo2661 | clpB1 | azo2661 | azo1566 | Hypothetical protein which carries at the C-terminus a DnaJ N-terminal domain. InterPro: DnaJ N-terminal domain (IPR001623) Pfam: DnaJ domain no signal peptide no TMHs. | Probable ATP-dependent Clp protease, ATP-binding subunit ClpB; Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE; Belongs to the ClpA/ClpB family. | 0.748 |
azo2661 | dnaK | azo2661 | azo1063 | Hypothetical protein which carries at the C-terminus a DnaJ N-terminal domain. InterPro: DnaJ N-terminal domain (IPR001623) Pfam: DnaJ domain no signal peptide no TMHs. | Chaperone protein DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family. | 0.963 |
azo2661 | groEL1 | azo2661 | azo0974 | Hypothetical protein which carries at the C-terminus a DnaJ N-terminal domain. InterPro: DnaJ N-terminal domain (IPR001623) Pfam: DnaJ domain no signal peptide no TMHs. | Chaperonin GroEL; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions. | 0.660 |
azo2661 | groEL3 | azo2661 | azo2366 | Hypothetical protein which carries at the C-terminus a DnaJ N-terminal domain. InterPro: DnaJ N-terminal domain (IPR001623) Pfam: DnaJ domain no signal peptide no TMHs. | Chaperonin GroEL; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions. | 0.660 |
azo2661 | grpE | azo2661 | azo1064 | Hypothetical protein which carries at the C-terminus a DnaJ N-terminal domain. InterPro: DnaJ N-terminal domain (IPR001623) Pfam: DnaJ domain no signal peptide no TMHs. | Probable heat shock protein GrpE; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several round [...] | 0.920 |
azo2661 | htpG | azo2661 | azo1425 | Hypothetical protein which carries at the C-terminus a DnaJ N-terminal domain. InterPro: DnaJ N-terminal domain (IPR001623) Pfam: DnaJ domain no signal peptide no TMHs. | Probable chaperon protein HtpG; Molecular chaperone. Has ATPase activity. | 0.948 |
clpA | azo0358 | azo1132 | azo0358 | ATP-dependent Clp protease ATP-binding subunit clpA. Homology to clpA of E. coli of 63% (sprot|CLPA_ECOLI). ATP-dependent specificity component of the clpP protease. It directs the protease to specific substrates. The primary function of the clpA-clpP complex appears to be the degradation of unfolded or abnormal proteins. InterPro: AAA-protein (ATPases associated with various cellular activities)(IPR003959); AAA ATPase superfamily (IPR003593); Clp amino terminus (IPR004176); chaperonins clpA/B (IPR001270); Bacterial typeII secretion system protein E (IPR001482) Pfam: Clp amino ternimal [...] | Putative two-component sensor kinase; Region start changed from 382943 to 383189 (246 bases). | 0.746 |
clpA | azo2661 | azo1132 | azo2661 | ATP-dependent Clp protease ATP-binding subunit clpA. Homology to clpA of E. coli of 63% (sprot|CLPA_ECOLI). ATP-dependent specificity component of the clpP protease. It directs the protease to specific substrates. The primary function of the clpA-clpP complex appears to be the degradation of unfolded or abnormal proteins. InterPro: AAA-protein (ATPases associated with various cellular activities)(IPR003959); AAA ATPase superfamily (IPR003593); Clp amino terminus (IPR004176); chaperonins clpA/B (IPR001270); Bacterial typeII secretion system protein E (IPR001482) Pfam: Clp amino ternimal [...] | Hypothetical protein which carries at the C-terminus a DnaJ N-terminal domain. InterPro: DnaJ N-terminal domain (IPR001623) Pfam: DnaJ domain no signal peptide no TMHs. | 0.748 |
clpA | dnaJ1 | azo1132 | azo1062 | ATP-dependent Clp protease ATP-binding subunit clpA. Homology to clpA of E. coli of 63% (sprot|CLPA_ECOLI). ATP-dependent specificity component of the clpP protease. It directs the protease to specific substrates. The primary function of the clpA-clpP complex appears to be the degradation of unfolded or abnormal proteins. InterPro: AAA-protein (ATPases associated with various cellular activities)(IPR003959); AAA ATPase superfamily (IPR003593); Clp amino terminus (IPR004176); chaperonins clpA/B (IPR001270); Bacterial typeII secretion system protein E (IPR001482) Pfam: Clp amino ternimal [...] | Chaperone protein DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...] | 0.767 |