STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
moxR1MoxR protein (MxaR protein). MAY BE INVOLVED IN THE REGULATION OF FORMATION OF ACTIVE METHANOL DEHYDROGENASE. TREMBL:Q883V0: 60% identity, 73% similarity SMART: SM00382; AAA InterPro: IPR003593; AAA_ATPase. IPR001270; Chaprnin_clpA/B. IPR003442; UPF0079. Pfam: PF02367; UPF0079; Pfam: Mg_chelatase:Magnesium chelatase, subunit ChlI ruvB: Holliday junction DNA helicase Ru No signal peptide and transmembrane helices; High confidence in function and specificity. (305 aa)    
Predicted Functional Partners:
azo1092
Conserved hypotetical membrane protein. Homology to RSp0111 of R. solanacearum of 41% (trembl|Q8XTJ7(SRS)) Pfam: Transglutaminase-like superfamily signal peptide probable 4 TMHs; Conserved hypothetical protein.
 
   
 0.958
azo1093
Conserved hypothetical membrane protein. Homology to RS03012 of Ralstonia solanacearum of 40% (trembl|Q8XTJ8) InterPro: Protein of unknown function DUF58 This domain is found in a family of prokaryotic proteins that have no known function. Proteins belonging to this family include hypothetical proteins from eubacteria and archaebacteria. Some of these proteins also contain the Von Willebrand factor, type A domain InterterPro: IPR002881; DUF58. Pfam: PF01882; DUF58; Non-secretory with low signal peptide probability (Signal P predicted). TMHMM predicted 2 transmembrane helices; Conserved [...]
 
  
 0.938
mltB
Putative membrane-bound lytic murein transglycosylase. homology to mltb of E. coli of 38% (sprot|MLTB_ECOLI) Murein-degrading enzyme. Catalyzes the cleavage of the glycosidic bonds between N-acetylmuramic acid and N- acetylglucosamine residues in peptidoglycan. May play a role in recycling of muropeptides during cell elongation and/or cell division. no domains prediced signal peptide no TMHs; Family membership.
       0.837
adiA
Putative orn/arg/lys decarboxylase. Homology to adiA of E. coli of 37% (sprot|ADIA_ECOLI). This family is composed of ornithine decarboxylases (ODC), arginine decarboxylases (ADC) and lysine decarboxylases (LDC), and belongs to the pyridoxal phosphate (PLP)-dependent aspartate aminotransferase domain superfamily (fold I). These enzymes catalyse the decarboxylation of ornithine,arginine, or lysine, respectively using PLP as a co-factor. Pfam: Orn/Lys/Arg decarboxylase no signal peptide no TMHs; Specificity unclear.
    
 
 0.806
azo2861
Hypothetical protein Rv1480/MT1527/Mb1516. TREMBL:Q7MUE8: 33% identity, 52% similarity. This domain is found in a family of prokaryotic proteins that have no known function. Proteins belonging to this family include hypothetical proteins from eubacteria and archaebacteria. Some of these proteins also contain the Von Willebrand factor, type A domain InterPro: IPR002881; DUF58. Pfam: PF01882; DUF58 Absence of transmembrane helices (TMHMM predicted) cmk: cytidylate kinase; Specificity unclear.
  
 0.752
azo1095
Histone deacetylases, acetoin utilization proteins and acetylpolyamine amidohydrolases are all members of an ancient protein superfamily, TREMBL:Q7VZF1 (58% identity); TREMBL:Q7NRU4 (57% identity). InterPro (IPR000286): Histone deacetylase family Pfam (PF00850): Histone deacetylase domain; Family membership.
       0.599
azo2864
Conserved hypothetical membrane protein. TREMBL:Q9CBL9: 33% identity; 52% similarity The von Willebrand factor is a large multimeric glycoprotein found in bloodplasma. Mutant forms are involved in the aetiology of bleeding disorders. In von Willebrand factor, the type A domain (vWF) is the prototype for a protein superfamily Hypothetical protein MAV335. InterPro:IPR002035; VWF_A. Pfam:PF00092; VWA; 1. SMART:SM00327; VWA 2_A_01_02: Multidrug resistance protein Presence of Signal peptide (SignalP predicted) Presence of 3 transmembrane helices (TMHMM predicted); Conserved hypothetical protein.
 
  
 0.535
azo2860
Conserved hypothetical membrane protein. Homology to PJS6w01004232 of Polaromonas sp. JS666 of 53% (gi|54028976|ref|ZP_00361120.1|(NBCI ENTREZ)). InterPro:IPR002035; VWF_A. The von Willebrand factor is a large multimeric glycoprotein found in blood plasma. Mutant forms are involved in the aetiology of bleeding disorders. In von Willebrand factor, the type A domain (vWF) is the prototype for a protein superfamily. Pfam:PF00092; VWA; 1. SMART:SM00327; VWA; 1. PROSITE:PS50234; VWFA; MIP: MIP family channel proteins. No signal peptide present. No. of TMH's: 3 (TMHMM predicted); Conserved h [...]
 
  
 0.534
norD
Nitric-oxide reductase accessory cytoplasmic protein; Nitric oxide reductase NorD protein. COMPONENT OF THE ANAEROBIC RESPIRATORY CHAIN THAT TRANSFORMS NITRATE TO DINITROGEN (DENITRIFICATION). FUNCTION UNKNOWN BUT ESSENTIAL FOR THE DENITRIFICATION PROCESS. 35% similarity to B. japonicum NorD. TREMBL:Q89QB3 InterPro:IPR002035; VWF_A. Pfam:PF00092; VWA; 1. InterPro:SM00327:von Willebrand factor type A domain SignalP:present. TMHMM: presence of TMHhelix; High confidence in function and specificity.
  
  
 0.424
Your Current Organism:
Azoarcus sp. BH72
NCBI taxonomy Id: 62928
Other names: A. sp. BH72
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