STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
rlmDPutative 23S rRNA (Uracil-5-) methyltransferase; Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA; Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. RlmD subfamily. (433 aa)    
Predicted Functional Partners:
azo1099
Conserved hypothetical protein. Homology to CV3581 of C.violaceum of 48% (tremble:Q7NS46) SM00558;JmjC:Probable enzymes, but of unknown functions,that regulate chromatin reorganisation processes. No signal peptide or TMH present. lytR_cpsA_psr: cell envelope-related fu.
       0.548
azo3706
Conserved hypothetical protein; Similar to TREMBL:Q89RW7 (50% identity,64% similarity); TREMBL:Q88IS2 (49% identity). InterPro (IPR000051); SAM (and some other nucleotide) binding motif.
   
 
 0.507
azo3711
Conserved hypothetical protein; Similar to SWISSPROT:P39367 (68% identity),TREMBL:Q8Z1C8 (66% identity).
   
 
 0.507
lysS
Lysyl-tRNA synthetase (EC 6.1.1.6) (Lysine--tRNA ligase) (LysRS); High confidence in function and specificity; Belongs to the class-II aminoacyl-tRNA synthetase family.
 
  
 0.501
azo3985
Sun protein; Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA.
  
  
 0.479
trmB
Conserved hypothetical tRNA (guanine-N7-)-methyltransferase; Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
  
 
 0.457
azo1101
Ribosomal large subunit pseudouridine synthase E (EC 4.2.1.70) (Uracil hydrolyase). Responsible for synthesis of pseudouridine from uracil-2457 in 23S ribosomal RNA; Family membership; Belongs to the pseudouridine synthase RsuA family.
       0.432
yggH
tRNA (guanine-N(7)-)-methyltransferase, 29% identity to SwissProt;Q8EBX8. SwissProt;Q8Y1I7(25% Identity),Q8FE22(25% identity). Has PF02390,Methyltransf_4,Putative methyltransferase;IPR003358; This is a family of putative methyltransferases. The aligned region contains the GXGXG S-AdoMet binding site suggesting a putative methyltransferase activity.
  
 
 0.425
azo3122
Conserved hypothetical protein; SUN protein; Specificity unclear; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
  
  
 0.413
pheT
Phenylalanyl-tRNA synthetase beta chain (EC 6.1.1.20) (Phenylalanine--tRNA ligase beta chain) (PheRS); High confidence in function and specificity; Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
 
  
 0.400
Your Current Organism:
Azoarcus sp. BH72
NCBI taxonomy Id: 62928
Other names: A. sp. BH72
Server load: low (36%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.