STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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crtIPhytoene dehydrogenase (EC 1.14.99.-) (Phytoene desaturase). Phytoene dehydrogenase (phytoene desaturase) is an enzyme of carotenoid biosynthesis that converts phytoene into zeta-carotene via the symmetrical introduction of two double bonds at the C-11 and C-11' positions of phytoene, TREMBL:Q8XYC4 (50% identity); SWISSPROT:P06108 (26% identity). InterPro (IPR008150): Bacterial-type phytoene dehydrogenase Pfam (Phytoene_dh): Phytoene dehydrogenase related enzyme; High confidence in function and specificity. (526 aa)    
Predicted Functional Partners:
crtB2
Putative phytoene synthase. Homology to crtB of Synechococcus sp. of 35% (SWISSPROT:CRTB_SYNP7 Is involved in the synthesis of carotenoids. Catalyzes the reaction from prephytoene diphosphate to phytoene. Pfam: Squalene/phytoene synthase no singal peptide no TMHs; Family membership.
 
 
 0.949
crtB1
Putative phytoene synthase. Homology to crtB of Synechococcus sp. of 30% (SWISSPROT:CRTB_SYNP7 Is involved in the synthesis of carotenoids. Catalyzes the reaction from prephytoene diphosphate to phytoene. Pfam: Squalene/phytoene synthase no singal peptide no TMHs; Family membership.
 
 
 0.911
ispA
Geranyltranstransferase; Geranylgeranyl pyrophosphate synthetase chloroplast precursor (GGPP synthetase) (GGPS) [Includes: Dimethylallyltransferase (EC 2.5.1.1); Geranyltranstransferase (EC 2.5.1.10); Farnesyltranstransferase (EC 2.5.1.29)]. catalyzes the trans-addition of the three molecules of ipp onto dmapp to form geranylgeranyl pyrophosphate. InterPro: Polyprenyl synthetase; High confidence in function and specificity; Belongs to the FPP/GGPP synthase family.
  
 
 0.707
azo1986
Conserved hypothetical protein; Entry name TREMBL:Q89PQ1 Prim. accession # Q89PQ1 Identities = 241/381 (63%) Thiolase, N-terminal domain (Pfam predicted) Prediction: Non-secretory protein Signal peptide probability: 0.00 Number of predicted TMHs: 0.
  
  
 0.707
azo1981
Conserved hypothetical indolepyruvate ferredoxin oxidoreductase, beta subunit. Homology to rsc1828 of R. solanacearum of 53% (trembl|Q8XYD0). Pfam: Pyruvate ferredoxin/flavodoxin oxidoreductase. no signal peptide. no TMHs; Conserved hypothetical protein.
 
     0.695
azo1978
Conserved hypothetical protein; TREMBL:Q89PP9: 66% identity, 79% similarity. InterPro:IPR007325; Cyclase. Pfam:PF04199; Cyclase No signal peptide present. Absence of trans-membrane helices (TMHMM predicted); Function unclear.
 
   
 0.685
azo1988
Conserved hypothetical protein; TREMBL:Q8XYC3: 64% identity, 75% similarity Proteins in this family are thought to be cyclase enzymes. They are found in proteins involved in antibiotic synthesis. However they are also found in organisms that do not make antibiotics pointing to a wider role for these proteins. The proteins contain a conserved motif HXGTHXDXPXH that is likely to form a part of the active site. InterPro:IPR007325; Cyclase. Pfam: PF04199; Cyclase Absence of signal peptide. Absence of transmembrane helices; Function unclear.
 
   
 0.682
azo1987
The short-chain dehydrogenases/reductases family (SDR) is a very large family of enzymes, most of which are known to be NAD- or NADP-dependent oxidoreductases,; Specificity unclear.
 
   
 0.672
carBb2
Hydroxylase large component of 1,2-dioxygenase protein complex, involved in aromatic compounds degradation. Putative 2'-aminobiphenyl-2,3-diol 1,2-dioxygenase, CarBb. Involved in the aerobic degradation of carbazole by P.resinovorans sp. strain CA10. XlyY: Benzoate 12-dioxygenase beta subunit (EC 1.14.12.10). DEGRADATION OF BENZOATE TO 2-HYDRO-12-DIHYDROXYBENZOATE (DHB); High confidence in function and specificity.
 
   
 0.669
azo1980
Conserved hypothetical indolepyruvate oxidoreductase, alpha subunit. Homology to mlr5448 of M. loti of 69% (trembl|Q98BS4). CATALYZES THE FERREDOXIN-DEPENDENT OXIDATIVE DECARBOXYLATION OF ARYLPYRUVATES (BY SIMILARITY). no signal peptide. no TMHs; Conserved hypothetical protein.
 
     0.667
Your Current Organism:
Azoarcus sp. BH72
NCBI taxonomy Id: 62928
Other names: A. sp. BH72
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