STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
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[Homology]
Score
azo1130S-adenosylmethionine:2-demethylmenaquinone methyltransferase; Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions. (161 aa)    
Predicted Functional Partners:
aceA
AceA protein; Isocitrate lyase. Homology to aceA of E. coli of 73% (sprot|ACEA_ECOLI). Isocitrate lyase is an enzyme that catalyzes the conversion of isocitrate to succinate and glyoxylate. This is the first step in the glyoxylate bypass, an alternative to the tricarboxylic acid cycle in bacteria, fungi and plants. InterPro: Isocitrate lyase (IPR000918) Pfam: Isocitrate lyase family no signal peptide no TMHs; High confidence in function and specificity.
 
    0.650
metH
Probable methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
     
 0.560
rhlE1
ATP-dependent RNA helicase; Family membership; Belongs to the DEAD box helicase family.
    
 
 0.518
rhlE2
Putative ATP-dependent RNA helicase rhlE; Family membership; Belongs to the DEAD box helicase family.
    
 
 0.518
deaD
ATP-dependent RNA helicase; DEAD-box RNA helicase involved in various cellular processes at low temperature, including ribosome biogenesis, mRNA degradation and translation initiation.
    
 
 0.518
rhlE3
Putative ATP-dependent RNA helicase; DEAD-box RNA helicase involved in ribosome assembly. Has RNA- dependent ATPase activity and unwinds double-stranded RNA.
    
 
 0.518
citE
Probable Citrate lyase beta chain(EC 4.1.3.6)(Citrase)(Citryl-CoA lyase subunit)(EC 4.1.3.34). In citrate-utilising prokaryotes, citrate lyase cleaves intracellular citrate into acetate and oxaloacetate, and is organised as a functional complex consisting of alpha,beta, and gamma subunits.The alpha subunit substitutes citryl for the acetyl group to form citryl-S-ACP. The beta subunit completes the reaction by cleaving the citryl to yield oxaloacetate and (regenerated) acetyl-S-ACP. Similar to the CitE protein from L.mesenteroides where is part of a gene cluster citCDEFG. SWISSPROT:CILB [...]
    
 0.480
rpe
Ribulose-phosphate 3-epimerase(also known as pentose-5-phosphate 3-epimerase, PPE or Rpe), is the enzyme that converts D-ribulose 5-phosphate into D-xylulose 5-phosphate in Calvin's reductive pentose phosphate cycle. 71%Ribul_P_3_epim. Pfam:PF00834; Ribul_P_3_epim; 1. TIGRFAMs:TIGR01163; rpe; 1; High confidence in function and specificity.
    
  0.465
azo1131
Conserved hypothetical protein. Homology to Daro03001685 of Dechloromonas aromatica of 46% (gi|41725028|ref|ZP_00151838.1|(NBCI ENTREZ)). No domains predicted. No TMHs. No signal peptide.
       0.455
azo0794
Arabinose 5-phosphate isomerase (EC 5.3.1.13). Catalyzes the interconversion of D-arabinose 5-phosphate and D-ribulose 5-phosphate (By similarity). InterPro: KpsF/GutQ family protein kpsF: KpsF/GutQ family protein; High confidence in function and specificity; Belongs to the SIS family. GutQ/KpsF subfamily.
    
  0.446
Your Current Organism:
Azoarcus sp. BH72
NCBI taxonomy Id: 62928
Other names: A. sp. BH72
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