Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
azo1160Conserved hypothetical membrane protein. Homology to mlr4286 of M. loti of 43% (trembl|Q98EE2) InterPro: IPR002781; DUF81.This domain is found in integral membrane proteins of prokaryotes which are uncharacterized Pfam:PF01925; DUF81 Signal peptide present and presence of 6 transmembrane helices; Conserved hypothetical protein. (260 aa)    
Predicted Functional Partners:
aceB
AceB protein; Malate synthase. Homology to aceB of A. eutropus of 73% (trembl|Q8VM95). CATALYTIC ACTIVITY: Acetyl-CoA + H(2)O + glyoxylate = S-malate + CoA. Acts in the glyoxylate bypass. Pfam: Malate synthase no TMHs 1 HTH; High confidence in function and specificity.
       0.735
azo1161
Transcriptional regulator, LysR family This protein activates the transcription of the lysA gene encoding diaminopimelate decarboxylase. LysR is also a negative regulator of its own expression. 29% 1 helixturnhelix PF03466 LysR_substrate; 1. HTH reporting nucleic acid binding motif; Specificity unclear.
       0.506
azo3987
Conserved hypothetical membrane protein. TREMBL:Q88FZ3: 44% identity, 60% similarity InterPro:IPR002781; DUF81.This domain is found in integral membrane proteins of prokaryotes which are uncharacterized Pfam:PF01925; DUF81 Signal peptide present and presence of 6 transmembrane helices; Conserved hypothetical protein.
  
     0.490
cobA2
Uroporphyrin-III C-methyltransferase (Urogen III methylase) (SUMT) (Uroporphyrinogen III methylase) (UROM). TIGRFAM: dph5: diphthine synthase; High confidence in function and specificity; Belongs to the precorrin methyltransferase family.
    
 0.457
Your Current Organism:
Azoarcus sp. BH72
NCBI taxonomy Id: 62928
Other names: A. sp. BH72
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