STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
nirDNitrite reductase [NAD(P)H] small subunit (EC 1.7.1.4). REQUIRED FOR ACTIVITY OF THE REDUCTASE. 66% simialr to the nirD protein from R. solanacearum,a probable nitrite reductase NADPH (small subunit) oxidoreductase protein [EC:1.7.1.4]. TREMBL:Q8XQK3. InterPro: Rieske iron-sulfur protein 2Fe-2S subunit In E.coli, the NADH-dependent nitrite reductase catalyzes the six-electron reduction of nitrite to ammonia and also catalyzes the two-electron reduction of hydroxylamine to ammonia. The enzyme is a FAD-flavoprotein, and also contains a siroheme and one 2Fe-2S center; Conserved hypothetic [...] (112 aa)    
Predicted Functional Partners:
nirB
Nitrite reductase [NAD(P)H] large subunit (EC 1.7.1.4). 76% EGF_like.IPR001327; FAD_pyr_redox. IPR007419;Fer2_BFD.IPR006066; Nir_Si.IPR006067; Nir_Sir_4Fe4S. IPR005117; NiR_SiR_beta_fer. IPR001100; Pyr_redox. Pfam: PF04324; Fer2_BFD; 1.PF01077; NIR_SIR; 1.PF03460; NIR_SIR_ferr; 1. PF00070; Pyr_redox; 1. In E.coli, the NADH-dependent nitrite reductase catalyzes the six-electron reduction of nitrite to ammonia and also catalyzes the two-electron reduction of hydroxylamine to ammonia. The enzyme is a FAD-flavoprotein, and also contains a siroheme and one 2Fe-2S center; High confidence in [...]
 0.987
nasC
Putative nitrate reducatse small subunit. Homology to nasC of K. oxytoca of 38% (trembl|Q48467). NasC probably mediates electron transfer from NADH to NasA, the nitrate reductase. InterPro: FAD-dependent pyridine nucleotide-disulphide oxidoreductase (IPR001327) Pfam: Pyridine nucleotide-disulfide oxidoreductase no signal peptide no TMHs; Family membership.
 0.963
camA
Probable putidaredoxin reductase (EC 1.18.1.-). Homology to camA of P. putida of 48% (sprot|CAMA_PSEPU). The oxidation of camphor by cytochrome p450-cam requires the participation of a flavoprotein, putidaredoxin reductase, and an iron-sulfur protein, putidaredoxin, to mediate the transfer of electrons from nadh to p450 for oxygen activation. Interpro: FAD-dependent pyridine nucleotide-disulphide oxidoreductase (IRP001327), NAD binding site (IPR000205) Pfam: Pyridine nucleotide-disulphide oxidoreductase no signal peptide no TMHs; Family membership.
 0.892
nirC
Putative nitrite transporter; 76% For/Nit_transpt. Pfam: PF01226; Form_Nir_trans; 1. In E. coli, NirC is a putative nitrite transporter which is a member of the FNT family of formate and nitrite transporters. The nirC gene is located in the nir operon which codes for a NADH-dependent nitrite reductase. NirC may function to import nitrite as a substrate for this enzyme complex. The nir operon is anaerobically expressed and is repressed by oxygen. TMhelix:6; High confidence in function and specificity.
 
  
 0.852
azo2929
Putative oxidoreductase. Homology to narC of C. perfringens of 27% (trembl|Q9WX91) InterPro: FAD-dependent pyridine nucleotide-disulphide oxidoreductase (IPR001327) Pfam: Pyridine nucleotide-disulfide oxidoreductase no signal peptide no TMHs purD: phosphoribosylamine--glycine lig; Family membership.
 
 0.834
cobA2
Uroporphyrin-III C-methyltransferase (Urogen III methylase) (SUMT) (Uroporphyrinogen III methylase) (UROM). TIGRFAM: dph5: diphthine synthase; High confidence in function and specificity; Belongs to the precorrin methyltransferase family.
  
  
 0.814
lapN
Phenol 2-monooxygenase p3 component,; High confidence in function and specificity.
   
  0.809
poxD
Probable phenol hydroxylase subunit,68% identity(84% similarity) to trEMBL:Q9RAF6,Phenol hydroxylase component [phyC] [Ralstonia sp. KN1]. TrEMBL;Q9ZNP4 Has PF02332:Methane/Phenol/Toluene Hydroxylase;IPR003430;Bacterial phenol hydroxylase (EC: 1.14.13.7) is a multicomponent enzyme that catabolises phenol and some of its methylated derivatives. This family contains both the P1 and P3 polypeptides of phenol hydroxlase and the alpha and beta chain of methane hydroxylase protein A. Methane hydroxylase protein A (EC: 1.14.13.25) is responsible for the initial oxygenation of methane to metha [...]
   
  0.809
nagAa
Naphthalene 12-dioxygenase system ferredoxin--NAD(+) reductase component COMPONENT OF NAPHTHALENE DIOXYGENASE (NDO) MULTICOMPONENT ENZYME SYSTEM WHICH CATALYZES THE INCORPORATION OF BOTH ATOMS OF MOLECULAR OXYGEN INTO NAPHTHALENE TO FORM CIS- NAPHTHALENE DIHYDRODIOL. TRANSFERS ELECTRONS FROM FERREDOXIN (NDOA) TO NADH; High confidence in function and specificity.
    
 0.800
azo1178
Putative serin/threonin protein kinase,; Family membership.
 
    0.759
Your Current Organism:
Azoarcus sp. BH72
NCBI taxonomy Id: 62928
Other names: A. sp. BH72
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