STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
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Coexpression
Experiments
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[Homology]
Score
pqqEPyrroloquinoline quinone synthesis protein E; Catalyzes the cross-linking of a glutamate residue and a tyrosine residue in the PqqA protein as part of the biosynthesis of pyrroloquinoline quinone (PQQ). (384 aa)    
Predicted Functional Partners:
pqqD
PqqD protein; Coenzyme PQQ synthesis protein D .This family contains several bacterial coenzyme PQQ synthesis protein D (PqqD) sequences. This protein is required for coenzyme pyrrolo-quinoline-quinone (PQQ) biosynthesis. 65% similarity with Klebsiella pneumoniae and 80%; Family membership.
 
  
 0.977
pqqC
Coenzyme PQQ synthesis protein C; Ring cyclization and eight-electron oxidation of 3a-(2-amino- 2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline-7,9- dicarboxylic-acid to PQQ.
 
  
 0.948
pqqB
Probable coenzyme PQQ synthesis protein B; May be involved in the transport of PQQ or its precursor to the periplasm; Belongs to the PqqB family.
 
  
 0.941
azo2935
Conserved hypothetical protein TMHMM2 reporting the presence of 1 TMH's. No Signal peptide present. Has 2 WD40 repeats;SMART;SM00320, Beta-transducin (G-beta) is one of the three subunits (alpha, beta, and gamma) of the guanine nucleotide-binding proteins (G proteins) which act as intermediaries in the transduction of signals generated by transmembrane receptors (see IPR001632). The alpha subunit binds to and hydrolyzes GTP; the functions of the beta and gamma subunits are less clear but they seem to be required for the replacement of GDP by GTP as well as for membrane anchoring and re [...]
 
  
 0.843
exaA5
Quinoprotein ethanol dehydrogenase precursor (QEDH). Oxidizes primary alcohols and also acts on secondary alcohol, but not highly active on methanol. 32% Bac_PQQ.IPR002372; Bac_PQQ_repeat. Pfam:PF01011; PQQ; 2. Signal peptide:present. SWISSPROT:DHET_GLUOX:O05542.30%; High confidence in function and specificity.
 
  
 0.761
exaA3
Quinoprotein ethanol dehydrogenase precursor (QEDH). Oxidizes primary alcohols and also acts on secondary alcohol, but not highly active on methanol. 53% Bac_PQQ.IPR002372; Bac_PQQ_repeat. Pfam:PF01011; PQQ; 2. Signal peptide:present. TMhelix:1; High confidence in function and specificity.
 
  
 0.752
exaA2
Quinoprotein ethanol dehydrogenase precursor (QEDH). Oxidizes primary alcohols and also acts on secondary alcohol, but not highly active on methanol. 73% Bac_PQQ.IPR002372; Bac_PQQ_repeat. Pfam:PF01011; PQQ; 2. Signal peptide:present; High confidence in function and specificity.
 
  
 0.746
ribAB
GTP cyclohydrolase II; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; Belongs to the DHBP synthase family.
    
  0.713
exaA4
Quinoprotein ethanol dehydrogenase precursor (QEDH). Oxidizes primary alcohols and also acts on secondary alcohol, but not highly active on methanol. 37% Bac_PQQ.IPR002372; Bac_PQQ_repeat. Pfam:PF01011; PQQ; 2. Signal peptide:present; High confidence in function and specificity.
 
  
 0.683
azo1799
The first part of the protein (2202 bases) is 37% Glyco_hydro_77. Pfam:PF02446; 4A_glucanotrans; 1.TIGRFAMs:TIGR00217; malQ; 1. GO:5975/4134. The second part of the protein (from the base 2128 to the end) is 39%; Function unclear; ORF5.
     
 0.670
Your Current Organism:
Azoarcus sp. BH72
NCBI taxonomy Id: 62928
Other names: A. sp. BH72
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