| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| aas | azo1194 | azo0150 | azo1194 | AAS bifunctional protein [Includes: 2-acylglycerophosphoethanolamine acyltransferase (2-acyl-GPE acyltransferase); Acyl-acyl carrier protein synthetase (Acyl-ACP synthetase)]. PLAYS A ROLE IN LYSOPHOSPHOLIPID ACYLATION. TRANSFERS FATTY ACIDS TO THE 1-POSITION VIA AN ENZYME-BOUND ACYL-ACP INTERMEDIATE IN THE PRESENCE OF ATP AND MG(2+). ITS PHYSIOLOGICAL FUNCTION IS TO REGENERATE PTDETN FROM 2-ACYL-GPE FORMED BY TRANSACYLATION REACTIONS OR DEGRADATION BY PHOSPHOLIPASE A1, TREMBL:Q8FEA6 (52% identity); SWISSPROT:P31119 (52% identity). Pfam (PF00501): AMP-binding enzyme. Pfam (PF01553): Ac [...] | Putative integral membrane efflux protein; Permease member of the Major Facilitator Superfamiliy (MFS)transporters. MFS are single-polypeptide secondary carriers capable only of transporting small solutes in response to chemiosmotic ion gradients. 2A0121: H+ Antiporter protein 24% similarity to NorA who confer relatively high resistance to hydrophilic quinolones such as norfloxacin, enoxacin, ofloxacin, and ciprofloxacin in S. aureus. 20% similarity to TapA a multidrug efflux pump wich confers low level of resistance to aminoglycosides and tetracycline in Mycobaterium fortuitum and M. [...] | 0.511 |
| aas | pabB | azo0150 | azo0198 | AAS bifunctional protein [Includes: 2-acylglycerophosphoethanolamine acyltransferase (2-acyl-GPE acyltransferase); Acyl-acyl carrier protein synthetase (Acyl-ACP synthetase)]. PLAYS A ROLE IN LYSOPHOSPHOLIPID ACYLATION. TRANSFERS FATTY ACIDS TO THE 1-POSITION VIA AN ENZYME-BOUND ACYL-ACP INTERMEDIATE IN THE PRESENCE OF ATP AND MG(2+). ITS PHYSIOLOGICAL FUNCTION IS TO REGENERATE PTDETN FROM 2-ACYL-GPE FORMED BY TRANSACYLATION REACTIONS OR DEGRADATION BY PHOSPHOLIPASE A1, TREMBL:Q8FEA6 (52% identity); SWISSPROT:P31119 (52% identity). Pfam (PF00501): AMP-binding enzyme. Pfam (PF01553): Ac [...] | Para-aminobenzoate synthase component I (EC 4.1.3.-) (ADC synthase). CATALYZES THE BIOSYNTHESIS OF 4-AMINO-4-DEOXYCHORISMATE (ADC) FROM CHORISMATE AND GLUTAMINE. InterPro: Anthranilate synthase component I and chorismate binding enzyme pabB: para-aminobenzoate synthase component I; Specificity unclear. | 0.685 |
| aas | pheA | azo0150 | azo1068 | AAS bifunctional protein [Includes: 2-acylglycerophosphoethanolamine acyltransferase (2-acyl-GPE acyltransferase); Acyl-acyl carrier protein synthetase (Acyl-ACP synthetase)]. PLAYS A ROLE IN LYSOPHOSPHOLIPID ACYLATION. TRANSFERS FATTY ACIDS TO THE 1-POSITION VIA AN ENZYME-BOUND ACYL-ACP INTERMEDIATE IN THE PRESENCE OF ATP AND MG(2+). ITS PHYSIOLOGICAL FUNCTION IS TO REGENERATE PTDETN FROM 2-ACYL-GPE FORMED BY TRANSACYLATION REACTIONS OR DEGRADATION BY PHOSPHOLIPASE A1, TREMBL:Q8FEA6 (52% identity); SWISSPROT:P31119 (52% identity). Pfam (PF00501): AMP-binding enzyme. Pfam (PF01553): Ac [...] | Bifunctional chorismate mutase/prephenate dehydratase P-protein, pheA,; High confidence in function and specificity. | 0.632 |
| argM | azo1194 | azo1195 | azo1194 | Probable acetylornithine transaminase. Homology to argM of E. coli of 45% (sprot|ARGM_ECOLI). Catalyzes the transmination of n(2)-succinylornithine and alpha-ketoglutarate into n(2)-succinylglutamate semialdehyde and glutamate. Can also act as a acetylornithine aminotransferase. Tigrfam: argD: acetylornithine and succinylornithine aminotransferases Pfam: Aminotransferse class-III no TMHs; High confidence in function and specificity. | Putative integral membrane efflux protein; Permease member of the Major Facilitator Superfamiliy (MFS)transporters. MFS are single-polypeptide secondary carriers capable only of transporting small solutes in response to chemiosmotic ion gradients. 2A0121: H+ Antiporter protein 24% similarity to NorA who confer relatively high resistance to hydrophilic quinolones such as norfloxacin, enoxacin, ofloxacin, and ciprofloxacin in S. aureus. 20% similarity to TapA a multidrug efflux pump wich confers low level of resistance to aminoglycosides and tetracycline in Mycobaterium fortuitum and M. [...] | 0.589 |
| azo1194 | aas | azo1194 | azo0150 | Putative integral membrane efflux protein; Permease member of the Major Facilitator Superfamiliy (MFS)transporters. MFS are single-polypeptide secondary carriers capable only of transporting small solutes in response to chemiosmotic ion gradients. 2A0121: H+ Antiporter protein 24% similarity to NorA who confer relatively high resistance to hydrophilic quinolones such as norfloxacin, enoxacin, ofloxacin, and ciprofloxacin in S. aureus. 20% similarity to TapA a multidrug efflux pump wich confers low level of resistance to aminoglycosides and tetracycline in Mycobaterium fortuitum and M. [...] | AAS bifunctional protein [Includes: 2-acylglycerophosphoethanolamine acyltransferase (2-acyl-GPE acyltransferase); Acyl-acyl carrier protein synthetase (Acyl-ACP synthetase)]. PLAYS A ROLE IN LYSOPHOSPHOLIPID ACYLATION. TRANSFERS FATTY ACIDS TO THE 1-POSITION VIA AN ENZYME-BOUND ACYL-ACP INTERMEDIATE IN THE PRESENCE OF ATP AND MG(2+). ITS PHYSIOLOGICAL FUNCTION IS TO REGENERATE PTDETN FROM 2-ACYL-GPE FORMED BY TRANSACYLATION REACTIONS OR DEGRADATION BY PHOSPHOLIPASE A1, TREMBL:Q8FEA6 (52% identity); SWISSPROT:P31119 (52% identity). Pfam (PF00501): AMP-binding enzyme. Pfam (PF01553): Ac [...] | 0.511 |
| azo1194 | argM | azo1194 | azo1195 | Putative integral membrane efflux protein; Permease member of the Major Facilitator Superfamiliy (MFS)transporters. MFS are single-polypeptide secondary carriers capable only of transporting small solutes in response to chemiosmotic ion gradients. 2A0121: H+ Antiporter protein 24% similarity to NorA who confer relatively high resistance to hydrophilic quinolones such as norfloxacin, enoxacin, ofloxacin, and ciprofloxacin in S. aureus. 20% similarity to TapA a multidrug efflux pump wich confers low level of resistance to aminoglycosides and tetracycline in Mycobaterium fortuitum and M. [...] | Probable acetylornithine transaminase. Homology to argM of E. coli of 45% (sprot|ARGM_ECOLI). Catalyzes the transmination of n(2)-succinylornithine and alpha-ketoglutarate into n(2)-succinylglutamate semialdehyde and glutamate. Can also act as a acetylornithine aminotransferase. Tigrfam: argD: acetylornithine and succinylornithine aminotransferases Pfam: Aminotransferse class-III no TMHs; High confidence in function and specificity. | 0.589 |
| azo1194 | azo3288 | azo1194 | azo3288 | Putative integral membrane efflux protein; Permease member of the Major Facilitator Superfamiliy (MFS)transporters. MFS are single-polypeptide secondary carriers capable only of transporting small solutes in response to chemiosmotic ion gradients. 2A0121: H+ Antiporter protein 24% similarity to NorA who confer relatively high resistance to hydrophilic quinolones such as norfloxacin, enoxacin, ofloxacin, and ciprofloxacin in S. aureus. 20% similarity to TapA a multidrug efflux pump wich confers low level of resistance to aminoglycosides and tetracycline in Mycobaterium fortuitum and M. [...] | Putative exonuclease of the beta-lactamase fold involved in RNA processing, N-terminal fragment; Family membership. | 0.507 |
| azo1194 | azo3289 | azo1194 | azo3289 | Putative integral membrane efflux protein; Permease member of the Major Facilitator Superfamiliy (MFS)transporters. MFS are single-polypeptide secondary carriers capable only of transporting small solutes in response to chemiosmotic ion gradients. 2A0121: H+ Antiporter protein 24% similarity to NorA who confer relatively high resistance to hydrophilic quinolones such as norfloxacin, enoxacin, ofloxacin, and ciprofloxacin in S. aureus. 20% similarity to TapA a multidrug efflux pump wich confers low level of resistance to aminoglycosides and tetracycline in Mycobaterium fortuitum and M. [...] | Putative exonuclease of the beta-lactamase fold involved in RNA processing, C-terminal fragment; Family membership. | 0.507 |
| azo1194 | hom | azo1194 | azo2081 | Putative integral membrane efflux protein; Permease member of the Major Facilitator Superfamiliy (MFS)transporters. MFS are single-polypeptide secondary carriers capable only of transporting small solutes in response to chemiosmotic ion gradients. 2A0121: H+ Antiporter protein 24% similarity to NorA who confer relatively high resistance to hydrophilic quinolones such as norfloxacin, enoxacin, ofloxacin, and ciprofloxacin in S. aureus. 20% similarity to TapA a multidrug efflux pump wich confers low level of resistance to aminoglycosides and tetracycline in Mycobaterium fortuitum and M. [...] | Homoserine dehydrogenase catalyzes NAD-dependent reduction of aspartate beta-semialdehyde into homoserine. This reaction is the third step in a pathway leading from aspartate to homoserine. Similar to TREMBL:Q9RAM9 (77%) and to pir|DEPSHA(PIR (Georgetown University) (56%). Pfam: Homoserine dehydrogenase; High confidence in function and specificity. | 0.508 |
| azo1194 | pabB | azo1194 | azo0198 | Putative integral membrane efflux protein; Permease member of the Major Facilitator Superfamiliy (MFS)transporters. MFS are single-polypeptide secondary carriers capable only of transporting small solutes in response to chemiosmotic ion gradients. 2A0121: H+ Antiporter protein 24% similarity to NorA who confer relatively high resistance to hydrophilic quinolones such as norfloxacin, enoxacin, ofloxacin, and ciprofloxacin in S. aureus. 20% similarity to TapA a multidrug efflux pump wich confers low level of resistance to aminoglycosides and tetracycline in Mycobaterium fortuitum and M. [...] | Para-aminobenzoate synthase component I (EC 4.1.3.-) (ADC synthase). CATALYZES THE BIOSYNTHESIS OF 4-AMINO-4-DEOXYCHORISMATE (ADC) FROM CHORISMATE AND GLUTAMINE. InterPro: Anthranilate synthase component I and chorismate binding enzyme pabB: para-aminobenzoate synthase component I; Specificity unclear. | 0.453 |
| azo1194 | pheA | azo1194 | azo1068 | Putative integral membrane efflux protein; Permease member of the Major Facilitator Superfamiliy (MFS)transporters. MFS are single-polypeptide secondary carriers capable only of transporting small solutes in response to chemiosmotic ion gradients. 2A0121: H+ Antiporter protein 24% similarity to NorA who confer relatively high resistance to hydrophilic quinolones such as norfloxacin, enoxacin, ofloxacin, and ciprofloxacin in S. aureus. 20% similarity to TapA a multidrug efflux pump wich confers low level of resistance to aminoglycosides and tetracycline in Mycobaterium fortuitum and M. [...] | Bifunctional chorismate mutase/prephenate dehydratase P-protein, pheA,; High confidence in function and specificity. | 0.482 |
| azo3288 | azo1194 | azo3288 | azo1194 | Putative exonuclease of the beta-lactamase fold involved in RNA processing, N-terminal fragment; Family membership. | Putative integral membrane efflux protein; Permease member of the Major Facilitator Superfamiliy (MFS)transporters. MFS are single-polypeptide secondary carriers capable only of transporting small solutes in response to chemiosmotic ion gradients. 2A0121: H+ Antiporter protein 24% similarity to NorA who confer relatively high resistance to hydrophilic quinolones such as norfloxacin, enoxacin, ofloxacin, and ciprofloxacin in S. aureus. 20% similarity to TapA a multidrug efflux pump wich confers low level of resistance to aminoglycosides and tetracycline in Mycobaterium fortuitum and M. [...] | 0.507 |
| azo3288 | azo3289 | azo3288 | azo3289 | Putative exonuclease of the beta-lactamase fold involved in RNA processing, N-terminal fragment; Family membership. | Putative exonuclease of the beta-lactamase fold involved in RNA processing, C-terminal fragment; Family membership. | 0.991 |
| azo3289 | azo1194 | azo3289 | azo1194 | Putative exonuclease of the beta-lactamase fold involved in RNA processing, C-terminal fragment; Family membership. | Putative integral membrane efflux protein; Permease member of the Major Facilitator Superfamiliy (MFS)transporters. MFS are single-polypeptide secondary carriers capable only of transporting small solutes in response to chemiosmotic ion gradients. 2A0121: H+ Antiporter protein 24% similarity to NorA who confer relatively high resistance to hydrophilic quinolones such as norfloxacin, enoxacin, ofloxacin, and ciprofloxacin in S. aureus. 20% similarity to TapA a multidrug efflux pump wich confers low level of resistance to aminoglycosides and tetracycline in Mycobaterium fortuitum and M. [...] | 0.507 |
| azo3289 | azo3288 | azo3289 | azo3288 | Putative exonuclease of the beta-lactamase fold involved in RNA processing, C-terminal fragment; Family membership. | Putative exonuclease of the beta-lactamase fold involved in RNA processing, N-terminal fragment; Family membership. | 0.991 |
| hom | azo1194 | azo2081 | azo1194 | Homoserine dehydrogenase catalyzes NAD-dependent reduction of aspartate beta-semialdehyde into homoserine. This reaction is the third step in a pathway leading from aspartate to homoserine. Similar to TREMBL:Q9RAM9 (77%) and to pir|DEPSHA(PIR (Georgetown University) (56%). Pfam: Homoserine dehydrogenase; High confidence in function and specificity. | Putative integral membrane efflux protein; Permease member of the Major Facilitator Superfamiliy (MFS)transporters. MFS are single-polypeptide secondary carriers capable only of transporting small solutes in response to chemiosmotic ion gradients. 2A0121: H+ Antiporter protein 24% similarity to NorA who confer relatively high resistance to hydrophilic quinolones such as norfloxacin, enoxacin, ofloxacin, and ciprofloxacin in S. aureus. 20% similarity to TapA a multidrug efflux pump wich confers low level of resistance to aminoglycosides and tetracycline in Mycobaterium fortuitum and M. [...] | 0.508 |
| hom | pabB | azo2081 | azo0198 | Homoserine dehydrogenase catalyzes NAD-dependent reduction of aspartate beta-semialdehyde into homoserine. This reaction is the third step in a pathway leading from aspartate to homoserine. Similar to TREMBL:Q9RAM9 (77%) and to pir|DEPSHA(PIR (Georgetown University) (56%). Pfam: Homoserine dehydrogenase; High confidence in function and specificity. | Para-aminobenzoate synthase component I (EC 4.1.3.-) (ADC synthase). CATALYZES THE BIOSYNTHESIS OF 4-AMINO-4-DEOXYCHORISMATE (ADC) FROM CHORISMATE AND GLUTAMINE. InterPro: Anthranilate synthase component I and chorismate binding enzyme pabB: para-aminobenzoate synthase component I; Specificity unclear. | 0.713 |
| hom | pheA | azo2081 | azo1068 | Homoserine dehydrogenase catalyzes NAD-dependent reduction of aspartate beta-semialdehyde into homoserine. This reaction is the third step in a pathway leading from aspartate to homoserine. Similar to TREMBL:Q9RAM9 (77%) and to pir|DEPSHA(PIR (Georgetown University) (56%). Pfam: Homoserine dehydrogenase; High confidence in function and specificity. | Bifunctional chorismate mutase/prephenate dehydratase P-protein, pheA,; High confidence in function and specificity. | 0.739 |
| pabB | aas | azo0198 | azo0150 | Para-aminobenzoate synthase component I (EC 4.1.3.-) (ADC synthase). CATALYZES THE BIOSYNTHESIS OF 4-AMINO-4-DEOXYCHORISMATE (ADC) FROM CHORISMATE AND GLUTAMINE. InterPro: Anthranilate synthase component I and chorismate binding enzyme pabB: para-aminobenzoate synthase component I; Specificity unclear. | AAS bifunctional protein [Includes: 2-acylglycerophosphoethanolamine acyltransferase (2-acyl-GPE acyltransferase); Acyl-acyl carrier protein synthetase (Acyl-ACP synthetase)]. PLAYS A ROLE IN LYSOPHOSPHOLIPID ACYLATION. TRANSFERS FATTY ACIDS TO THE 1-POSITION VIA AN ENZYME-BOUND ACYL-ACP INTERMEDIATE IN THE PRESENCE OF ATP AND MG(2+). ITS PHYSIOLOGICAL FUNCTION IS TO REGENERATE PTDETN FROM 2-ACYL-GPE FORMED BY TRANSACYLATION REACTIONS OR DEGRADATION BY PHOSPHOLIPASE A1, TREMBL:Q8FEA6 (52% identity); SWISSPROT:P31119 (52% identity). Pfam (PF00501): AMP-binding enzyme. Pfam (PF01553): Ac [...] | 0.685 |
| pabB | azo1194 | azo0198 | azo1194 | Para-aminobenzoate synthase component I (EC 4.1.3.-) (ADC synthase). CATALYZES THE BIOSYNTHESIS OF 4-AMINO-4-DEOXYCHORISMATE (ADC) FROM CHORISMATE AND GLUTAMINE. InterPro: Anthranilate synthase component I and chorismate binding enzyme pabB: para-aminobenzoate synthase component I; Specificity unclear. | Putative integral membrane efflux protein; Permease member of the Major Facilitator Superfamiliy (MFS)transporters. MFS are single-polypeptide secondary carriers capable only of transporting small solutes in response to chemiosmotic ion gradients. 2A0121: H+ Antiporter protein 24% similarity to NorA who confer relatively high resistance to hydrophilic quinolones such as norfloxacin, enoxacin, ofloxacin, and ciprofloxacin in S. aureus. 20% similarity to TapA a multidrug efflux pump wich confers low level of resistance to aminoglycosides and tetracycline in Mycobaterium fortuitum and M. [...] | 0.453 |