STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
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Textmining
[Homology]
Score
azo1194Putative integral membrane efflux protein; Permease member of the Major Facilitator Superfamiliy (MFS)transporters. MFS are single-polypeptide secondary carriers capable only of transporting small solutes in response to chemiosmotic ion gradients. 2A0121: H+ Antiporter protein 24% similarity to NorA who confer relatively high resistance to hydrophilic quinolones such as norfloxacin, enoxacin, ofloxacin, and ciprofloxacin in S. aureus. 20% similarity to TapA a multidrug efflux pump wich confers low level of resistance to aminoglycosides and tetracycline in Mycobaterium fortuitum and M. [...] (411 aa)    
Predicted Functional Partners:
argM
Probable acetylornithine transaminase. Homology to argM of E. coli of 45% (sprot|ARGM_ECOLI). Catalyzes the transmination of n(2)-succinylornithine and alpha-ketoglutarate into n(2)-succinylglutamate semialdehyde and glutamate. Can also act as a acetylornithine aminotransferase. Tigrfam: argD: acetylornithine and succinylornithine aminotransferases Pfam: Aminotransferse class-III no TMHs; High confidence in function and specificity.
       0.589
aas
AAS bifunctional protein [Includes: 2-acylglycerophosphoethanolamine acyltransferase (2-acyl-GPE acyltransferase); Acyl-acyl carrier protein synthetase (Acyl-ACP synthetase)]. PLAYS A ROLE IN LYSOPHOSPHOLIPID ACYLATION. TRANSFERS FATTY ACIDS TO THE 1-POSITION VIA AN ENZYME-BOUND ACYL-ACP INTERMEDIATE IN THE PRESENCE OF ATP AND MG(2+). ITS PHYSIOLOGICAL FUNCTION IS TO REGENERATE PTDETN FROM 2-ACYL-GPE FORMED BY TRANSACYLATION REACTIONS OR DEGRADATION BY PHOSPHOLIPASE A1, TREMBL:Q8FEA6 (52% identity); SWISSPROT:P31119 (52% identity). Pfam (PF00501): AMP-binding enzyme. Pfam (PF01553): Ac [...]
  
 
 0.511
hom
Homoserine dehydrogenase catalyzes NAD-dependent reduction of aspartate beta-semialdehyde into homoserine. This reaction is the third step in a pathway leading from aspartate to homoserine. Similar to TREMBL:Q9RAM9 (77%) and to pir|DEPSHA(PIR (Georgetown University) (56%). Pfam: Homoserine dehydrogenase; High confidence in function and specificity.
    
  0.508
azo3288
Putative exonuclease of the beta-lactamase fold involved in RNA processing, N-terminal fragment; Family membership.
   
    0.507
azo3289
Putative exonuclease of the beta-lactamase fold involved in RNA processing, C-terminal fragment; Family membership.
   
    0.507
pheA
Bifunctional chorismate mutase/prephenate dehydratase P-protein, pheA,; High confidence in function and specificity.
     
 0.482
pabB
Para-aminobenzoate synthase component I (EC 4.1.3.-) (ADC synthase). CATALYZES THE BIOSYNTHESIS OF 4-AMINO-4-DEOXYCHORISMATE (ADC) FROM CHORISMATE AND GLUTAMINE. InterPro: Anthranilate synthase component I and chorismate binding enzyme pabB: para-aminobenzoate synthase component I; Specificity unclear.
   
 
 0.453
Your Current Organism:
Azoarcus sp. BH72
NCBI taxonomy Id: 62928
Other names: A. sp. BH72
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