STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
mntA2Manganese transport system ATP-binding protein mntA. This protein is probably a component of a manganese permease a binding protein-dependent ATP-driven transport system (mntABC). Probably responsible for energy coupling to the transport system. 40% AAA_ATPase.IPR003439,AAA ATPase superfamily; ABC_transporter. Pfam: PF00005; ABC_tran; 1. This operon probably is also involved in other cations uptake like Fe,Cu and Zn; High confidence in function and specificity. (265 aa)    
Predicted Functional Partners:
mntB2
Putative manganese transport system permease protein; Part of the ABC transporter complex mntABC involved in manganese import. Probably responsible for the translocation of the substrate across the membrane. 28% IPR001626; ABC_transpt3. Pfam; PF00950; ABC-3; 1. TmHelix:8 This operon probably is also involved in other cations uptake like Fe,Cu and Zn; High confidence in function and specificity.
 
 0.995
mntB3
Putative manganese transport system permease protein; Part of the ABC transporter complex mntABC involved in manganese import. Probably responsible for the translocation of the substrate across the membrane. Similar to the permease protein, MntB in Synechocystis 6803. 30% IPR001626; ABC_transpt3. Pfam; PF00950; ABC-3; 1. This operon probably is also involved in other cations uptake like Fe,Cu and Zn; High confidence in function and specificity.
 
 0.995
mntC2
Putative periplasmic solute binding protein; Part of the ABC transporter complex mntABC involved in manganese uptake. 28% Similar to the putative periplasmic-binding protein MntC precursor in N gonorrhoaeae, also involved in the resistance to oxidative stress. TREMBL:Q9F4F6 InterPro:IPR006128; Lipoprotein_4.IPR006127; SBP_bac_9. Pfam:PF01297; SBP_bac_9; 1. Signal peptide present.TMHelix:1 This operon probably is also involved in other cations uptake like Fe,Cu and Zn.This protein also could act as an adhesin which is involved on adherence to extracellular matrix; High confidence in fun [...]
 
 
 0.985
mntB1
Putative manganese transport system, permease protein; Part of the ABC transporter complex mntABC involved in manganese import. Probably responsible for the translocation of the substrate across the membrane. Similar to the permease protein, MntB in Synechocystis 6803. 30% IPR001626; ABC_transpt3. Pfam; PF00950; ABC-3; 1. This operon probably is also involved in other cations uptake like Fe,Cu and Zn; High confidence in function and specificity.
 
 0.978
mntC1
Part of the ABC transporter complex mntABC involved in manganese uptake. 41% Similar to the putative periplasmic-binding protein MntC precursor in E.coli. The MntC protein is also involved in the resistance to oxidative stress in N gonorrhoaeae. TREMBL E.coli:Q9F4F6. InterPro:IPR006128; Lipoprotein_4.IPR006127; SBP_bac_9. Pfam:PF01297; SBP_bac_9; 1. Signal peptide present.TMHelix:1 This operon probably is also involved in other cations uptake like Fe,Cu and Zn; High confidence in function and specificity.
 
 
 0.950
ubiB
Probable ubiquinone biosynthesis protein; Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis. Belongs to the ABC1 family. UbiB subfamily.
      0.554
fur
Ferric uptake regulation protein (Ferric uptake regulator)Fur. Acts as a global negative controlling element employing Fe(2+) as a cofactor to bind the operator of the repressed genes. Regulator for biosynthesis of the siderophore alcaligin E. InterPro: Ferric uptake regulator family TIGR00011: conserved hypothetical protein; High confidence in function and specificity.
 
  
 0.511
azo0644
Putative regulator protein, probably involved in the regulation of cation uptake systems. 32% FUR.IPR009058; Wing_hlx_DNA_bnd. Pfam:PF01475; FUR; 1.Fur family protein 30%; Function unclear.
  
  
 0.427
ccmC
Probable heme exporter protein C; Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes; Belongs to the CcmC/CycZ/HelC family.
    
  0.413
Your Current Organism:
Azoarcus sp. BH72
NCBI taxonomy Id: 62928
Other names: A. sp. BH72
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