STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
azo1225Sigma-54 dependent transcriptional regulator; Some bacterial regulatory proteins activate the expression of genes from promoters recognized by core RNA polymerase associated with the alternative sigma-54 factor. These have a conserved domain of about 230 residues involved in the ATP-dependent interaction with sigma-54, TREMBL:Q8RM05 (41% identity); TREMBL:Q880V5 (32% identity). Pfam (PF02954): Bacterial regulatory protein,Fis family. Pfam (PF00158): Sigma-54 interaction domain. HTH reporting nucleic acid binding motif; Family membership. (686 aa)    
Predicted Functional Partners:
rpoN2
RNA polymerase sigma-54 factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.
  
  
 0.773
rpoN1
RNA polymerase sigma-54 factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.
  
  
 0.771
dmpM
Phenol hydroxylase P2 protein (Phenol 2-monooxygenase P2 component)68% similarity to SWISSPROT:P19731,Pseudomonas sp DmpM or Phenol hydroxylase protein component P2, this protein lacks redox co-factors and is required for optimal turnover of Phenol hydroxylase. Phenol hydroxylase catabolises phenol and some of its methylated derivatives in the first step of phenol biodegradation, and is required for growth on phenol. The multicomponent enzyme is made up of P0, P1, P2, P3, P4 and P5 polypeptides. Pfam:PF02406, InterPro:IPR003454 91% similarity with hypothetical protein Rgel01002820 [Rub [...]
 
     0.450
azo1224
Hypothetical membrane protein. No homology to the data bank. No domains predicted. No signal peptide. 1 TMH.
       0.450
azo1221
Conserved hypothetical aromatic/alkene monooxygenase, subunit beta Homology to blr3679 of B. japonicum of 53% (trembl|Q89P04(SRS) Bacterial aromatic/alkene monooxygenase is a multicomponent enzyme that catabolises phenol and some of its methylated derivatives (like methane and toulene). Interpro: Methane/Penol/Toluene hydroxylase (IPR003430) Pfam: Methane/Penol/Toluene hydroxylase (PF02332) no signal peptide no TMHs; Specificity unclear.
 
     0.409
Your Current Organism:
Azoarcus sp. BH72
NCBI taxonomy Id: 62928
Other names: A. sp. BH72
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