STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
cydAProbable cytochrome bd type terminal oxidase,subunit I. Homology to cydA of A. vinelandii of 67% (sprot|CYDA_AZOVI). Cytochrome bd type terminal oxidases catalyse quinol dependent, Na+ independent oxygen uptake. Members of this family are integral membrane proteins and contain a protoheame IX center B558. It may play an important role in microaerobic nitrogen fixation. InterPro: Cytochrome bd ubiquinol oxidase subunit I (IPR002585) Pfam: Bacterial cytochrome ubiquinol oxidase no singal peptide 9 TMHs; High confidence in function and specificity. (522 aa)    
Predicted Functional Partners:
cydB
Probable cytochrome bd type terminal oxidase,subunit II; Cytochrome D ubiquinol oxidase subunit II (EC 1.10.3.-) (Cytochrome BD-I oxidase subunit II). Cytochrome bd type terminal oxidases catalyse quinol dependent, Na+ independent oxygen uptake. Members of this family are integral membrane proteins and contain a protoheame IX center B558. It may play an important role in microaerobic nitrogen fixation. Tigrfam: cydB: cytochrome d ubiquinol oxidase subunit II Pfam: cytochrome oxidase subunit II no signal peptide 8 TMHs; High confidence in function and specificity.
 
 0.997
cioB
Probable cyanide insensitive terminal oxidase,subunit II. Homology to cioB of P. aeruginosa of 40% (trembl|O07441). Tigrfam: cydB: cytochrome d ubiquinol oxidase, subunit II Pfam: cytochrome oxidase, subunit II no signal peptide 8 TMHs; High confidence in function and specificity.
 
 
 0.985
azo1233
Hypothetical membrane protein. no homology to to the data bank. no domains predicted. no signal peptide. 1 TMHs.
       0.773
azo1230
Conserved hypothetical membrane protein, 40% identity (49% Similarity) to TrEMBL;Q6D7F7. Signa P reporting Signal peptide present. TMHMM2 reporting 2 TMH's present; Conserved hypothetical protein.
  
    0.656
azo1234
Probable ranscriptional regulator,; Specificity unclear.
       0.554
cioA
Probable cyanide insensitive terminal oxidase,subunit I Homology to cioA of P. aeruginose of 44% (TREMBL:O07440) InterPro: Cytochrome bd ubiquinol oxidase subunit I (IPR002585) Pfam: Bacterial cytochrome ubiquinol oxidase no signal peptide no TMHs; High confidence in function and specificity.
  
  
 
0.466
petB
Ubiquinol-cytochrome c reductase cytochrome b protein; Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis.
    
 0.459
ccoN
Probable cytochrome c oxidase, cbb3-type, subunit I. Homology to ccoN of R. capsulatus of 62% (sprot|COX1_RHOCA). CYTOCHROME C OXIDASE IS THE COMPONENT OF THE RESPIRATORY CHAIN THAT CATALYZES THE REDUCTION OF OXYGEN TO WATER. SUBUNITS 1- 3 FORM THE FUNCTIONAL CORE OF THE ENZYME COMPLEX. CO I IS THE CATALYTIC SUBUNIT OF THE ENZYME. ELECTRONS ORIGINATING IN CYTOCHROME C OR A QUINOL ARE TRANSFERRED TO THE BIMETALLIC CENTER FORMED BY A HIGH-SPIN HEME AND COPPER B. Tigrfam: ccoN: cytochrome c oxidase cbb3-type Pfam: cytochrome c and quinol oxidase polyppeptide no signal peptide 12 TMHs; Hig [...]
    
 0.454
rubA
Probable rubredoxin. Homology to ruba of A. calcoaceticus of 42% (sprot|RUBR_ACIAD). Involved in the hydrocarbon hydroxylating system to convert dodecane to lauric acid, which transfers electrons from NADH to rubredoxin reductase and then through rubredoxin to alkane 1 monooxygenase. Pfam: Rubredoxin no singal peptide no TMHs; Family membership.
  
  
 0.441
coxA
Probable cytochrome c oxidase, subunit I; Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1-3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B.
     
 0.420
Your Current Organism:
Azoarcus sp. BH72
NCBI taxonomy Id: 62928
Other names: A. sp. BH72
Server load: low (20%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.