STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
qhpCProbable quinohemoprotein amine dehydrogenase,gamma subunit. Homology to qhnDH of P. putida of 54% (sprot|QADG_PSEPK(SRS). Quinoproteins are a class of amine-oxidising enzymes that catalyse the oxidation of biological amines, using quinone as a redox cofactor to store reducing equivalents. Quinohemoprotein amine dehydrogenase (QH-AmDH) from bacteria represents a new class of quinoproteins that contains both quinone and one or two hemes as redox active groups. The presence of extra redox active groups allows for intramolecular electron transfer. QH-AmDH is a heterotrimeric enzyme contai [...] (108 aa)    
Predicted Functional Partners:
qhpA
Probable quinohemoprotein amine dehydrogenase,alpha subunit. Homology to qhpA of P.putida of 50% (gi|18655859|pdb|1JMZ|A(PDB (RCSB))). Quinoproteins are a class of amine-oxidising enzymes that catalyse the oxidation of biological amines, using quinone as a redox cofactor to store reducing equivalents. Quinohemoprotein amine dehydrogenase (QH-AmDH) from bacteria represents a new class of quinoproteins that contains both quinone and one or two hemes as redox active groups. The presence of extra redox active groups allows for intramolecular electron transfer. QH-AmDH is a heterotrimeric e [...]
 
 
 
 0.991
qhpB
Probable quinohemoprotein amine dehydrogenase,alpha subunit. Homology to qhpB of P.putida of 50% (gi|34809688|pdb|1PBY|B(PDB (RCSB))). Quinoproteins are a class of amine-oxidising enzymes that catalyse the oxidation of biological amines, using quinone as a redox cofactor to store reducing equivalents. Quinohemoprotein amine dehydrogenase (QH-AmDH) from bacteria represents a new class of quinoproteins that contains both quinone and one or two hemes as redox active groups. The presence of extra redox active groups allows for intramolecular electron transfer. QH-AmDH is a heterotrimeric e [...]
 
 
   0.991
qhpX
Conserved hypothetical qinohemoprotein amine dehydrogenase, unknown subunit. Homology to P. putida of 71% (gi|16950513|dbj|BAB72009.1|(NBCI ENTREZ)). InterPro:IPR000385; MoaA_NifB_PqqE. IPR007197; Radical_SAM. Pfam:PF04055; Radical_SAM. No signal peptide. No TMHs; Family membership.
 
     0.952
azo2935
Conserved hypothetical protein TMHMM2 reporting the presence of 1 TMH's. No Signal peptide present. Has 2 WD40 repeats;SMART;SM00320, Beta-transducin (G-beta) is one of the three subunits (alpha, beta, and gamma) of the guanine nucleotide-binding proteins (G proteins) which act as intermediaries in the transduction of signals generated by transmembrane receptors (see IPR001632). The alpha subunit binds to and hydrolyzes GTP; the functions of the beta and gamma subunits are less clear but they seem to be required for the replacement of GDP by GTP as well as for membrane anchoring and re [...]
   
   0.845
azo3207
Conserved hypothetical secreted protein. Homology to PA1688 of Pseudomonas aeruginosa of 54% (trembl|Q9X6R1(SRS)). No domains predicted. Signal p reporting signal peptide present. NO TMH present; Conserved hypothetical protein.
   
   0.845
maub
Methylamine dehydrogenase heavy chain precursor (MADH):- Methylamine dehydrogenase carries out the oxidation of methylamine. Electrons are passed from methylamine dehydrogenase to amicyanin. Entry name SWISSPROT:DHMH_METEX Prim. accession # Q49124 Identities = 100/339 (29%) Prediction: Signal peptide Signal peptide probability: 1.000 Number of predicted TMHs: 0; Family membership.
   
   0.843
subC
Subtilisin Savinase precursor, 36% identity to SwissProt; P29600. Has PF00082, Subtilase family;IPR000209, Pept_S8_S53;Subtilases are a family of serine proteases. They appear to have independently and convergently evolved an Asp/Ser/His catalytic triad, like that found in the trypsin serine proteases (see Trypsin). Structure is an alpha/beta fold containing a 7-stranded parallel beta sheet, order 2314567. PROSITE;) PS00136; SUBTILASE_ASP; 1. PS00137; SUBTILASE_HIS; 1. PS00138; SUBTILASE_SER; 1.
 
   
 0.820
exaB1
Probable cytochrome c550. Homology to exaB of P. aeruginosa of 57% (trembl|Q9Z4P8) Cytochrome c550 is an essential component of the quinoprotein ethanol oxidation system InterPro: Cytochrome c class I ((IPR003088) Pfam: Cytochrome c signal peptide no TMHs; High confidence in function and specificity.
 
 
   0.791
azo1238
Conserved hypothetical secreted protein. Homology to ebA2217 of Azoarcus sp. EbN1 of 32% (gnl|keqq|eba:ebA2217(KEGG)). C-terminus is not homolog to COG0644. signal peptide present. no TMHS; Conserved hypothetical protein.
 
     0.785
exaB2
Putative cytochrome c550. Homology to exaB of P. aeruginosa of 37% (trembl|Q9Z4P8). Cytochrome c550 is an essential component of the quinoprotein ethanol oxidation. InterPro: Cytochrome c class I (IPR003088) Pfam: cytochrome c signal peptide no TMHs; Function unclear.
 
 
   0.783
Your Current Organism:
Azoarcus sp. BH72
NCBI taxonomy Id: 62928
Other names: A. sp. BH72
Server load: low (28%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.