STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
azo1246Conserved hypothetical mandelate racemase. Homology to bll6730 of B. japonicum of 76% (trembl|Q89FH0) Mandelate racemase and muconate lactonizing enzyme are two bacterial enzymes involved in aromatic acid catabolism. They catalyze mechanistically distinct reactions yet they are related at the level of their primary, quaternary (homooctamer) and tertiary structures. InterPro: Mandelate racemase/muconate lactonizing enzyme family (IPR001354) Pfam: Mandelate racemase/muconate lactonizing enzyme, N-terminal domain; Mandelate racemase/muconate lactonizing enzyme, C-terminal domain; Specific [...] (388 aa)    
Predicted Functional Partners:
gnl
Gluconolactonase precursor (D-glucono-delta-lactone lactonohydrolase).HYDROLYZES THE GLUCONOLACTONE FORMED BY GLUCOSE-FRUCTOSE OXIDOREDUCTASE AND THAT FORMED IN AEROBIC CONDITIONS BY THE GLUCOSE DEHYDROGENASE PRESENT. 30% SMP-30. Pfam:PF03758; SMP-30; 1. Signal peptide: present; High confidence in function and specificity.
 
  
 0.652
dapA
Dihydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
    
 0.609
ligI
Probable 2-pyrone-4,6-dicarboxylate hydrolase. Homology to ligI of S. paucimobilis of 55% (tremble:O87170) Pfam: Amidohydrolase no signal peptide no TMHs; High confidence in function and specificity.
    
 0.604
azo0857
38% PfkB.Family of carbohydrate kinases Pfam:PF00294; PfkB; 1; Specificity unclear.
    
 0.601
dnaB
DnaB protein; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins. Belongs to the helicase family. DnaB subfamily.
  
    0.535
yeaU
Tartrate dehydrogenase catalyzes the reduction of tartrate to oxaloglycolate. Similar to sprot|TTUC_ECOLI (75%) and to sprot|TTUC_PSEPU (76%). Pfam (PF00180): Isocitrate and isopropylmalate dehydrogenases; High confidence in function and specificity.
  
     0.529
gdhAlpha1
Putative glucose dehydrogenase alpha subunit. Homology to gdhAlpha of B. cepacia of 29% (trembl|Q8GQE7) InterPro: NAD binding site (IPR000205) Pfam: GMC oxidoreductase no signal peptide no TMHs; Function unclear.
 
  
  0.486
panE2
2-dehydropantoate 2-reductase; Ketopantoate reductase (KPA reductase) (KPR). Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid (By similarity). TIGRFAM: apbA_panE: 2-dehydropantoate 2-reductas; High confidence in function and specificity.
  
    0.478
azo3873
Putative glucase dehydrogenase alpha subunit. Homology to gdhalspha of B. cepacia of 31% (trembl|Q8GQE7). Pfam: GMC oxidoreductase no signal peptide no TMHs; Function unclear.
 
  
  0.470
apbA2
Putative 2-dehydropantoate 2-reductase (EC 1.1.1.169) (KPA reductase) (KPR). Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid (By similarity). apbA_panE: 2-dehydropantoate 2-reductase; Specificity unclear.
  
    0.447
Your Current Organism:
Azoarcus sp. BH72
NCBI taxonomy Id: 62928
Other names: A. sp. BH72
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