STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
azo1252Conserved hypothetical membrane protein. Homology to XCC3430 of Xanthomonas campestris of 38% (trembl:Q8P5B1). Has PF04892, VanZ like family;IPR006976; This family contains several examples of the VanZ protein,but also contains examples of phosphotransbutyrylases. VanZ confers low-level resistance to the glycopeptide antibiotic teicoplanin (Te). Analysis of cytoplasmic peptidoglycan precursors, accumulated in the presence of ramoplanin, showed that VanZ-mediated Te resistance does not involve incorporation of a substituent of D-alanine into the peptidoglycan precursors. no signal pepti [...] (102 aa)    
Predicted Functional Partners:
azo1830
Putative TonB-denpendent receptor; Similar to FepA, an iron regulated outer membrane protein. FepA is a receptor for the siderophore complex ferric enterobactin and for colcins B and D. INVOLVED IN THE INITIAL STEP OF IRON UPTAKE BY BINDING FERRIC ENTEROBACTIN THAT ALLOWS E. COLI TO EXTRACT IRON FROM THE ENVIRONMENT. ilvC: ketol-acid reductoisomerase; Function unclear.
  
     0.662
azo0798
Hypothetical secreted protein. No homology to the data bank. No domains predicted. No TMHs. Signal peptide present.
  
     0.598
azo0952
Conserved hypothetical protein, 38% identity (50% similarity) to TrEMBL;Q7WXG4 Signal Peptide Present.TMH not Present. Has PF04471:Restriction endonuclease;(IPR007560:Mrr_cat):Prokaryotic family found in type II restriction enzymes containing the hallmark (D/E)-(D/E)XK active site. Presence of catalytic residues implicates this region in the enzymatic cleavage of DNA. PF01396:Topoisomerase DNA binding C4 zinc finger;(IPR000380 DNA_tpisomrase):Prokaryotic topoisomerase I, otherwise known as relaxing enzyme,untwisting enzyme or swivelase, catalyses the ATP-independent breakage of single- [...]
  
     0.584
azo1251
Conserved hypothetical peptidase. Homology to cv0266 of C. violaceum of 58% (cvi:CV0266). InterPro: Peptidase family U32 Pfam: Peptidase family U32 no signal peptide no TMHs; Family membership.
       0.477
azo1253
Conserved hypothetical protein; Similar to the GdhB protein, a putative glucose dehydrogenase-B, periplasmic protein [EC:1.1.5.2], from Synechocystis. SPTR: P73001. Signal peptide:present.
       0.475
azo3727
Conserved hypothetical secreted protein. Homology to ebA3180 of Azoarcus sp. EbN1 of 57% (gi|56477224|ref|YP_158813.1|(NBCI ENTREZ)). No domains predicted Signal Peptide present. No TMH reported present; Conserved hypothetical protein.
  
     0.473
azo3728
Probable lipoprotein, 58% similarity to TrEMBL:Q8XWT8 PROBABLE LIPOPROTEIN [RS01163] [Ralstonia solanacearum (Pseudomonas solanacearum)]. Has PF04355:IPR007450:SmpA / OmlA family;Lipoprotein Bacterial outer membrane lipoprotein, possibly involved in in maintaining the structural integrity of the cell envelope [1]. Lipid attachment site is a conserved N terminal cysteine residue. Sometimes found adjacent to the OmpA domain (OmpA). Signal peptide present. NO TMH reported present; Family membership.
  
     0.460
azo0966
Hemerythrin-like protein, 49% Identity to SProt;Q8Y1B3. Has PF01814, Hemerythrin HHE cation binding domain; IPR002063, Hemerythrin; Iteration of the HHE family found it to be related to Hemerythrin. It also demonstrated that what has been described as a single domain in fact consists of two cation binding domains. Members of this family occur all across nature and are involved in a variety of processes. For instance, in Nereis diversicolor P80255 binds Cadmium so as to protect the organism from toxicity. However Hemerythrin is classically described as Oxygen-binding through two attache [...]
  
     0.441
azo3077
Conserved hypothetical protein. Homology to xcc3092 of X. campestris of 51% (trembl|Q8P678). Pfam: Plasmid stabilisation system protein. Members of this family are involved in plasmid stabilisation. The exact molecular function of this protein is not known. no signal peptide. no TMHs.
  
     0.433
azo0483
Conserved hypothetical secreted protein. Homology to PA4874 of P.aeruginosa of 36% (trembl|Q9HUT9(SRS)) No domains predicted. Signal petide present. No TMH present; Conserved hypothetical protein.
  
     0.431
Your Current Organism:
Azoarcus sp. BH72
NCBI taxonomy Id: 62928
Other names: A. sp. BH72
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